Výsledky vyhledávání - "Simpson, Gordon"

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Evaluation of tools for differential gene expression analysis by RNA-seq on a 48 biological replicate experiment

Autor: Schurch, Nicholas J., Schofield, Pieta, Gierliński, Marek, Cole, Christian, Sherstnev, Alexander, Singh, Vijender, Wrobel, Nicola, Gharbi, Karim, Simpson, Gordon G., Owen-Hughes, Tom, Blaxter, Mark, Barton, Geoffrey J.

An RNA-seq experiment with 48 biological replicates in each of 2 conditions was performed to determine the number of biological replicates ($n_r$) required, and to identify the most effective statistical analysis tools for identifying differential ge

Externí odkaz: http://arxiv.org/abs/1505.02017

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Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment

Autor: Gierliński, Marek, Cole, Christian, Schofield, Pietà, Schurch, Nicholas J., Sherstnev, Alexander, Singh, Vijender, Wrobel, Nicola, Gharbi, Karim, Simpson, Gordon, Owen-Hughes, Tom, Blaxter, Mark, Barton, Geoffrey J.

High-throughput RNA sequencing (RNA-seq) is now the standard method to determine differential gene expression. Identifying differentially expressed genes crucially depends on estimates of read count variability. These estimates are typically based on

Externí odkaz: http://arxiv.org/abs/1505.00588

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Improved annotation of 3-prime untranslated regions and complex loci by combination of strand-specific Direct RNA Sequencing, RNA-seq and ESTs

Autor: Schurch, Nick, Cole, Christian, Sherstnev, Alexander, Song, Junfang, Duc, Céline, Storey, Kate G., McLean, W. H. Irwin, Brown, Sara J., Simpson, Gordon G., Barton, Geoffrey J.

Publikováno v: PLoS ONE 9(4) (2014): e94270

The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct annotation is particularly important when interpreting the results of RNA-seq experiments where short sequence reads are map

Externí odkaz: http://arxiv.org/abs/1311.2494

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