Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Simoun Icho"'
Autor:
Simoun Icho, Jennifer S. Ward, John Tam, Larry K. Kociolek, Casey M. Theriot, Roman A. Melnyk
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Intestinal bile acids play an essential role in the Clostridioides difficile lifecycle having been shown in vitro to modulate various aspects of pathogenesis, including spore germination, vegetative growth, and more recently the action of the primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13fc026fceba1b971155e1fac6b0000
https://doi.org/10.1073/pnas.2301252120
https://doi.org/10.1073/pnas.2301252120
Autor:
Heather K. Kroh, Stacey A. Rutherford, Simoun Icho, Roman A. Melnyk, Casey M. Theriot, D. Borden Lacy, Evelyn Utama, John Kit Chung Tam, Rodolfo F. Gómez-Biagi, Kathleen E. Orrell
Publikováno v:
Proc Natl Acad Sci U S A
Significance Clostridioides difficile is a bacterial pathogen of global importance that is a major cause of hospital-acquired diarrhea. Antibiotic-mediated disruptions to the gut microbiota and associated metabolome promote C. difficile growth and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d3b3b06f70eb6fef56779047f23233
https://doi.org/10.1073/pnas.1916965117
https://doi.org/10.1073/pnas.1916965117
Autor:
Simoun Icho, Roman A. Melnyk
Publikováno v:
Trends in pharmacological sciences. 40(3)
Clostridium difficile (Clostridioides difficile) is a toxin-producing, multidrug-resistant bacterium. Inhibiting the effects of toxins, which are responsible for the symptoms of disease, is viewed as a promising non-antibiotic approach to treat C. di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92a6857bd0cf2a6d8d38b03c0d465f6
https://pubmed.ncbi.nlm.nih.gov/30482680
https://pubmed.ncbi.nlm.nih.gov/30482680