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Conduction Disturbances and Outcome After Surgical Aortic Valve Replacement in Patients With Bicuspid and Tricuspid Aortic Stenosis.

Autor: Wedin JO; Cardio-Thoracic Translational Medicine Lab, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Departments of Surgical Sciences, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Sweden. (J.O.W., V.N. S.R., O.E.S., E.S., K-H.G.)., Näslund V; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Sweden. (J.O.W., V.N. S.R., O.E.S., E.S., K-H.G.)., Rodin S; Cardio-Thoracic Translational Medicine Lab, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Departments of Surgical Sciences, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Sweden. (J.O.W., V.N. S.R., O.E.S., E.S., K-H.G.)., Simonson OE; Cardio-Thoracic Translational Medicine Lab, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Departments of Surgical Sciences, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Sweden. (J.O.W., V.N. S.R., O.E.S., E.S., K-H.G.)., Flachskampf FA; Medical Sciences, Uppsala University, Sweden. (F.A.F., S.K.J.).; Department of Clinical Physiology and Cardiology, Uppsala University Hospital, Sweden. (F.A.F., S.K.J.)., James SK; Medical Sciences, Uppsala University, Sweden. (F.A.F., S.K.J.).; Department of Clinical Physiology and Cardiology, Uppsala University Hospital, Sweden. (F.A.F., S.K.J.).; Uppsala Clinical Research Center, Sweden. (S.K.J.)., Ståhle E; Cardio-Thoracic Translational Medicine Lab, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Departments of Surgical Sciences, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Sweden. (J.O.W., V.N. S.R., O.E.S., E.S., K-H.G.)., Grinnemo KH; Cardio-Thoracic Translational Medicine Lab, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Departments of Surgical Sciences, Uppsala University, Sweden. (J.O.W., S.R., O.E.S., E.S., K-H.G.).; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Sweden. (J.O.W., V.N. S.R., O.E.S., E.S., K-H.G.).

Publikováno v: Circulation [Circulation] 2024 Oct 23. Date of Electronic Publication: 2024 Oct 23.

Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies.

Autor: Beusch CM; Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden., Simonson OE; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden.; Department of Cardio-Thoracic Surgery and Anesthesia, Uppsala University Hospital, 751 85, Uppsala, Sweden., Wedin JO; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden.; Department of Cardio-Thoracic Surgery and Anesthesia, Uppsala University Hospital, 751 85, Uppsala, Sweden., Sabatier P; Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden.; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden.; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, 2200, Copenhagen, Denmark., Felldin U; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden.; Department of Cardio-Thoracic Surgery and Anesthesia, Uppsala University Hospital, 751 85, Uppsala, Sweden., Kadekar S; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden., Österholm C; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 77, Stockholm, Sweden., Végvári Á; Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden., Zubarev RA; Division of Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77, Stockholm, Sweden., Fromell K; Rudbeck Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 85, Uppsala, Sweden., Nilson B; Rudbeck Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, 751 85, Uppsala, Sweden., James S; Department of Medical Sciences, Uppsala University, 752 37, Uppsala, Sweden., Ståhle E; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden.; Department of Cardio-Thoracic Surgery and Anesthesia, Uppsala University Hospital, 751 85, Uppsala, Sweden., Grinnemo KH; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden.; Department of Cardio-Thoracic Surgery and Anesthesia, Uppsala University Hospital, 751 85, Uppsala, Sweden., Rodin S; Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, 752 37, Uppsala, Sweden. sergey.rodin@surgsci.uu.se.; Department of Cardio-Thoracic Surgery and Anesthesia, Uppsala University Hospital, 751 85, Uppsala, Sweden. sergey.rodin@surgsci.uu.se.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2023 Aug 26; Vol. 80 (9), pp. 268. Date of Electronic Publication: 2023 Aug 26.

Noninvasive detection of any-stage cancer using free glycosaminoglycans.

Autor: Bratulic S; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden., Limeta A; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden., Dabestani S; Department of Translational Medicine, Division of Urological Cancers, Lund University, 20502, Lund 205 02, Sweden.; Department of Urology, Kristianstad Central Hospital, Region Skåne, Kristianstad 291 33, Sweden., Birgisson H; Department of Surgical Sciences, Uppsala University Hospital, Uppsala 751 85, Sweden., Enblad G; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 751 85, Sweden., Stålberg K; Department of Women's and Children's, Health Uppsala University, Uppsala 751 85, Sweden., Hesselager G; Department of Neurosurgery, Uppsala University Hospital, Uppsala 751 85, Sweden., Häggman M; Department of Urology, Uppsala University Hospital, Uppsala 751 85, Sweden., Höglund M; Institution of Medical Sciences, Uppsala University Hospital, Uppsala 751 85, Sweden., Simonson OE; Department of Surgical Sciences, Uppsala University Hospital, Uppsala 751 85, Sweden.; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, Uppsala 751 85, Sweden., Stålberg P; Department of Surgical Sciences, Uppsala University Hospital, Uppsala 751 85, Sweden., Lindman H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 751 85, Sweden., Bång-Rudenstam A; Department of Clinical Sciences Lund, Section of Oncology and Pathology, Lund University, Lund 221 85, Sweden., Ekstrand M; Department of Molecular and Clinical Medicine, Institute of Medicine Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Kumar G; Vancouver Prostate Centre, Vancouver, BC V6H 3Z6, Canada.; Department of Urologic Sciences, University of British Columbia, Vancouver, BC V5Z 1M9, Canada., Cavarretta I; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale San Raffaele, Milan 20132, Italy., Alfano M; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale San Raffaele, Milan 20132, Italy., Pellegrino F; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale San Raffaele, Milan 20132, Italy., Mandel-Clausen T; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093., Salanti A; Centre for Medical Parasitology at Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.; Department of Infectious Disease Copenhagen, University Hospital, Copenhagen 2300, Denmark., Maccari F; Department of Life Sciences, University of Modena and Reggio Emilia, Modena 411 25, Italy., Galeotti F; Department of Life Sciences, University of Modena and Reggio Emilia, Modena 411 25, Italy., Volpi N; Department of Life Sciences, University of Modena and Reggio Emilia, Modena 411 25, Italy., Daugaard M; Vancouver Prostate Centre, Vancouver, BC V6H 3Z6, Canada.; Department of Urologic Sciences, University of British Columbia, Vancouver, BC V5Z 1M9, Canada., Belting M; Department of Clinical Sciences Lund, Section of Oncology and Pathology, Lund University, Lund 221 85, Sweden., Lundstam S; Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.; Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Stierner U; Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Nyman J; Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.; Department of Respiratory Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Bergman B; Department of Respiratory Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Edqvist PH; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 751 85, Sweden., Levin M; Department of Molecular and Clinical Medicine, Institute of Medicine Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.; Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Salonia A; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale San Raffaele, Milan 20132, Italy.; Università Vita-Salute San Raffaele, Milan 201 32, Italy., Kjölhede H; Department of Urology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.; Department of Urology, Sahlgrenska University Hospital, Gothenburg 413 45, Sweden., Jonasch E; The University of Texas MD Anderson Cancer Center, Houston, TX 77030., Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden.; BioInnovation Institute, Copenhagen 2200, Denmark., Gatto F; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden.; Department of Oncology-Pathology, Karolinska Institute, Stockholm 171 64, Sweden.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Dec 13; Vol. 119 (50), pp. e2115328119. Date of Electronic Publication: 2022 Dec 05.

Diversity of respiratory parameters and metabolic adaptation to low oxygen tension in mesenchymal stromal cells.

Autor: Olesen K; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76, Stockholm, Sweden.; School of Bioscience, University of Skövde, 541 28, Skövde, Sweden., Moruzzi N; The Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76, Stockholm, Sweden., Bulatovic I; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76, Stockholm, Sweden., Folmes C; Departments of Cardiovascular Medicine, And Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ, 85259, USA., Jeon R; Departments of Cardiovascular Medicine, And Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ, 85259, USA., Felldin U; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden., Terzic A; Departments of Cardiovascular Medicine, And Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ, 85259, USA., Simonson OE; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, 751 85, Uppsala, Sweden., Le Blanc K; Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, 141 86, Stockholm, Sweden., Österholm C; Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76, Stockholm, Sweden., Berggren PO; The Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76, Stockholm, Sweden., Schiffer T; Department of Physiology and Pharmacology, Karolinska Institutet, 171 77, Stockholm, Sweden., Rodin S; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, 751 85, Uppsala, Sweden.; Endocrinology Research Centre, Moscow, 115478, Russia., Tilevik A; School of Bioscience, University of Skövde, 541 28, Skövde, Sweden., Grinnemo KH; Department of Surgical Sciences, Uppsala University, 751 85, Uppsala, Sweden.; Department of Cardiothoracic Surgery and Anesthesiology, Uppsala University Hospital, 751 85, Uppsala, Sweden.

Publikováno v: Metabolism open [Metabol Open] 2022 Feb 03; Vol. 13, pp. 100167. Date of Electronic Publication: 2022 Feb 03 (Print Publication: 2022).