Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Simonetta Wallin"'
Autor:
Kasparas Petkevicius, Henrik Palmgren, Matthew S. Glover, Andrea Ahnmark, Anne-Christine Andréasson, Katja Madeyski-Bengtson, Hiroki Kawana, Erik L. Allman, Delaney Kaper, Martin Uhrbom, Liselotte Andersson, Leif Aasehaug, Johan Forsström, Simonetta Wallin, Ingela Ahlstedt, Renata Leke, Daniel Karlsson, Hernán González-King, Lars Löfgren, Ralf Nilsson, Giovanni Pellegrini, Nozomu Kono, Junken Aoki, Sonja Hess, Grzegorz Sienski, Marc Pilon, Mohammad Bohlooly-Y, Marcello Maresca, Xiao-Rong Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The regulation of cellular phosphatidylethanolamine (PE) acyl chain composition is poorly understood. Here, the authors show that TLCD1 and TLCD2 proteins mediate the formation of monounsaturated fatty acid-containing PE species and promote the progr
Externí odkaz:
https://doaj.org/article/15464563b39b4d54986a8c040d9d92b8
Autor:
Stefano Bartesaghi, Kristina Wallenius, Daniel Hovdal, Mathias Liljeblad, Simonetta Wallin, Niek Dekker, Louise Barlind, Nigel Davies, Frank Seeliger, Maria Sörhede Winzell, Sima Patel, Matt Theisen, Luis Brito, Nils Bergenhem, Shalini Andersson, Xiao-Rong Peng
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 500-513 (2022)
Fibroblast growth factor 21 (FGF21) is a promising therapeutic agent for treatment of type 2 diabetes (T2D) and non-alcoholic steatohepatitis (NASH). We show that therapeutic levels of FGF21 were achieved following subcutaneous (s.c.) administration
Externí odkaz:
https://doaj.org/article/870f12a5c5cf429dbef9b12f15e31262
Autor:
Henrik, Palmgren, Kasparas, Petkevicius, Stefano, Bartesaghi, Andrea, Ahnmark, Mario, Ruiz, Ralf, Nilsson, Lars, Löfgren, Matthew S, Glover, Anne-Christine, Andréasson, Liselotte, Andersson, Cécile, Becquart, Michael, Kurczy, Bengt, Kull, Simonetta, Wallin, Daniel, Karlsson, Sonja, Hess, Marcello, Maresca, Mohammad, Bohlooly-Y, Xiao-Rong, Peng, Marc, Pilon
Increased saturated fatty acid levels in membrane phospholipids have been implicated in the development of metabolic disease. Here, we tested the hypothesis that increased saturated fatty acid (SFA) content in cell membranes negatively impacts adipoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602e4660fb2096f0c15018ddd50c1efd
https://doi.org/10.2337/figshare.21782726.v2
https://doi.org/10.2337/figshare.21782726.v2
Autor:
Noemi Szekely, Xiaoqiu Wu, Marianna Yanez Arteta, Alexander J. Kvist, Johan Bergenholtz, Lennart Lindfors, Simonetta Wallin, Stefano Bartesaghi, Tomas Kjellman, Aurel Radulescu, Aleksandra P. Dabkowska
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 115(15), E3351-E3360 (2018). doi:10.1073/pnas.1720542115
Proceedings of the National Academy of Sciences of the United States of America 115(15), E3351-E3360 (2018). doi:10.1073/pnas.1720542115
Significance mRNA treatments represent an exciting approach to cure diseases that cannot be tackled with current therapeutics. However, the delivery of mRNA to target cells remains a challenge, but among the existing alternatives, lipid nanoparticles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a9b611772405ff42c0018c3a5ee2e5
https://pubmed.ncbi.nlm.nih.gov/29588418
https://pubmed.ncbi.nlm.nih.gov/29588418
Autor:
Stefano Bartesaghi, Simonetta Wallin, Anna Forslöw, Remi A. Momo, Patrick Seale, Per-Arne Svensson, Xiao-Rong Peng, Li Huang, Stefan Hallen, Eva K. Carlsson
Publikováno v:
Molecular Endocrinology. 29:130-139
Heat-producing beige/brite (brown-in-white) adipocytes in white adipose tissue have the potential to suppress metabolic disease in mice and hold great promise for the treatment of obesity and type 2 diabetes in humans. Here, we demonstrate that human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9cd81c668f59a709849e7e4628a304
https://doi.org/10.1210/me.2014-1295
https://doi.org/10.1210/me.2014-1295
Autor:
Martin E. Lidell, Paula Itkonen, Zahra Arani, Fredrik Westberg, Tommy Nilsson, Xiao-Rong Peng, Julia Fernandez-Rodriguez, Sven Enerbäck, Markku Laakso, Valentina Sukonina, Erin L. Seifert, Adrienne Gowing, Rickard Westergren, Mary-Ellen Harper, Mikael Heglind, Simonetta Wallin
Publikováno v:
Diabetes
OBJECTIVE Previous findings demonstrate that enhanced expression of the forkhead transcription factor Foxc2 in adipose tissue leads to a lean and insulin-sensitive phenotype. These findings prompted us to further investigate the role of Foxc2 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd3d7c79eff67792dae428ac03da14d
https://pubmed.ncbi.nlm.nih.gov/21270254
https://pubmed.ncbi.nlm.nih.gov/21270254