Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Simonetta Pulciani"'
Autor:
Simonetta, Pulciani, Emanuele, Nutile
Publikováno v:
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. 36(1)
This review aims at analysing the links between medicine and spirituality, two seemingly distant concepts. Medicine at its beginnings was imbued with rituals that invoked the intervention of supernatural powers, as man were unable to treat diseases a
Publikováno v:
Annali dell'Istituto superiore di sanita. 53(3)
Hippocrates was the first to raise awareness of medicine as a science. He asserted the body being a unified whole and emphasized the importance of preventive and predictive medicine, spurring physicians to foster patient collaboration. Recent achieve
Publikováno v:
Recenti progressi in medicina. 108(7)
The Human Genome Project and the "-omics" technologies will in future provide genetic maps and biosynthetic pathways permitting personalized medical interventions directed at maintaining or restoring wellbeing. This is reflected in the strategy aims
Publikováno v:
Annali dell'Istituto superiore di sanita. 53(2)
Patients need clinical competence, appropriate diagnosis and therapies in overcoming their disease. Yet this is insufficient. The illness experience tends to frighten people and the resulting emotional aspects could become relevant factors in coping
Autor:
Virgilia Toccaceli, Daniela Rotondi, Simonetta Pulciani, Lorenzo Giannantonio, Rodolfo Cotichini, Sonia Brescianini, Tatjana Dukic, C D'Ippolito, Lorenza Nisticò, Maria Antonietta Stazi, Corrado Fagnani, Emanuela Medda, Valeria Patriarca
Publikováno v:
Twin Research and Human Genetics. 9:799-805
Since its start as a database of ‘possible twins’, the Italian Twin Register has developed remarkably in terms of twin approach and recruitment, data-management tools, the cohorts enrolled, and the breadth of information gathered, making the Ital
Publikováno v:
Journal of Cancer
Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty years ago. This, and other extraordinary scientific g
Autor:
Simonetta, Pulciani, Anna, Di Lonardo, Corrado, Fagnani, Cristina, D'Ippolito, Roberto, Bomprezzi, Maria Antonietta, Stazi
Publikováno v:
Annali dell'Istituto superiore di sanita. 42(2)
The completion of the Human Genome Project, and the innovations introduced in biotechnology are changing how to study twins. Here, we summarize some molecular studies performed on populations of discordant monozygotic twins (MZ) applying microarrays.
Publikováno v:
Nature. 298:343-347
A transforming gene isolated from T24 human bladder carcinoma cells is closely related to the BALB murine sarcoma virus (MSV) onc gene (v-bas). This transforming gene is localized to a 4.6 kilobase pair (kbp) region and is expressed as a 1.2-kbp poly
Publikováno v:
Proceedings of the National Academy of Sciences. 80:4679-4683
It has been recently shown that malignant activation of the c-has/bas proto-oncogene in T24 human bladder carcinoma cells was mediated by a single point mutation. A deoxyguanosine located at position 35 of the first exon of this proto-oncogene was su
Autor:
Anne V. Lauver, Eugenio Santos, Keith C. Robbins, Linda K. Long, Mariano Barbacid, Simonetta Pulciani
Publikováno v:
Proceedings of the National Academy of Sciences. 79:2845-2849
The presence of dominant transforming genes in human tumor cell lines has been investigated. High molecular weight DNAs isolated from cell lines established from carcinomas and sarcomas of various organs as well as from a glioblastoma and two melanom