Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Simonetta Oliaro-Bosso"'
Autor:
Clarissa Caroli, Giovanna Baron, Giorgio Cappellucci, Virginia Brighenti, Larissa Della Vedova, Francesca Fraulini, Simonetta Oliaro-Bosso, Andrea Alessandrini, Alfonso Zambon, Gigliola Lusvardi, Giancarlo Aldini, Marco Biagi, Lorenzo Corsi, Federica Pellati
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30291- (2024)
Policosanols (PCs) are bioactive compounds extracted from different natural waxes. In this work, the purification, characterization and assessment of the antioxidant and anti-inflammatory activity was carried out on PCs from an innovative source, i.e
Externí odkaz:
https://doaj.org/article/a315ad7f226e4487942f8f7b08b062dd
Autor:
Tomasz M. Wróbel, Katyayani Sharma, Iole Mannella, Simonetta Oliaro-Bosso, Patrycja Nieckarz, Therina Du Toit, Clarissa Daniela Voegel, Maria Natalia Rojas Velazquez, Jibira Yakubu, Anna Matveeva, Søren Therkelsen, Flemming Steen Jørgensen, Amit V. Pandey, Agnese C. Pippione, Marco L. Lolli, Donatella Boschi, Fredrik Björkling
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1349 (2023)
This study reports on the synthesis and evaluation of novel compounds replacing the nitrogen-containing heterocyclic ring on the chemical backbone structure of cytochrome P450 17α-hydroxylase/12,20-lyase (CYP17A1) inhibitors with a phenyl bearing a
Externí odkaz:
https://doaj.org/article/40c682e275f24df7b4e877a00335408d
Autor:
Daniela Chirio, Elena Peira, Simona Sapino, Giulia Chindamo, Simonetta Oliaro-Bosso, Salvatore Adinolfi, Chiara Dianzani, Francesca Baratta, Marina Gallarate
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 560 (2021)
Bevacizumab (BVZ) is a monoclonal antibody that binds to human vascular endothelial growth factor A (VEGF-A) and inhibits the interaction between VEGF-A and VEGF receptors, thus blocking the angiogenesis. Repeated intravitreal injections of BVZ for t
Externí odkaz:
https://doaj.org/article/575ecb3c8dec468288dc4742b169c143
Autor:
Elena Peira, Giulia Chindamo, Daniela Chirio, Simona Sapino, Simonetta Oliaro-Bosso, Erica Rebba, Pavlo Ivanchenko, Marina Gallarate
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 258 (2021)
Bevacizumab (BVZ), a recombinant humanized monoclonal antibody, has recently been proposed as a topical application in the treatment of anterior segment neovascularization; however, as there are some disadvantages in the administration of common eye-
Externí odkaz:
https://doaj.org/article/1fdf49590c8e40f1b486e2136bbe5e5a
Autor:
Simona Sapino, Elena Peira, Daniela Chirio, Giulia Chindamo, Stefano Guglielmo, Simonetta Oliaro-Bosso, Raffaella Barbero, Cristina Vercelli, Giovanni Re, Valentina Brunella, Chiara Riedo, Antonio Maria Fea, Marina Gallarate
Publikováno v:
Nanomaterials, Vol 9, Iss 10, p 1461 (2019)
Endophthalmitis is a rare, but serious, intravitreal inflammatory disorder that can arise after cataract surgery. The intracameral injection of 1 mg cefuroxime (CEF) followed by three-times daily antibiotic topical administration for a week is genera
Externí odkaz:
https://doaj.org/article/ec9e9ee796ec4f8eafb7053f2b8991d1
Autor:
Natascia Bruni, Carlo Della Pepa, Simonetta Oliaro-Bosso, Enrica Pessione, Daniela Gastaldi, Franco Dosio
Publikováno v:
Molecules, Vol 23, Iss 10, p 2478 (2018)
There is a growing body of evidence to suggest that cannabinoids are beneficial for a range of clinical conditions, including pain, inflammation, epilepsy, sleep disorders, the symptoms of multiple sclerosis, anorexia, schizophrenia and other conditi
Externí odkaz:
https://doaj.org/article/2fbd061ff2314d129e1f812e79d6e3a4
Autor:
Simonetta Oliaro-Bosso, Giulia Caron, Silvia Taramino, Giuseppe Ermondi, Franca Viola, Gianni Balliano
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22134 (2011)
In oxidosqualene cyclases (OSCs), an enzyme which has been extensively studied as a target for hypocholesterolemic or antifungal drugs, a lipophilic channel connects the surface of the protein with the active site cavity. Active site and channel are
Externí odkaz:
https://doaj.org/article/e61102611c974e0687e5cd32818bfb56
Autor:
Adinolfi, Alex Fissore, Mauro Marengo, Valentina Santoro, Giorgio Grillo, Simonetta Oliaro-Bosso, Giancarlo Cravotto, Fabrizio Dal Piaz, Salvatore
Publikováno v:
Processes; Volume 11; Issue 7; Pages: 2064
Bromelain is a mixture of cysteine endopeptidase usually extracted from pineapple juice and is used for the treatment of various human diseases and in industrial applications. Bromelain demand is quickly increasing, and its recovery from pineapple re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::919a31aa279d6389e81ee7bd6cb16092
Publikováno v:
IUBMB Life. 74:715-722
Iron-sulfur clusters are prosthetic groups that are assembled on their acceptor proteins through a complex machine centered on a desulfurase enzyme and a transient scaffold protein. Studies to establish the mechanism of cluster formation have so far
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31814ee4cd1979b3a3709462c72265a
https://doi.org/10.1002/iub.2618
https://doi.org/10.1002/iub.2618
Autor:
Martina Daga, Salvatore Adinolfi, Donald Poirier, Gianni Balliano, Giulia D'Arrigo, Simonetta Oliaro-Bosso, Marco Lucio Lolli, Francesca Spyrakis, Terenzio Ferrante
Publikováno v:
Biochimie. 170:106-117
Cholesterol biosynthesis is a multistep process in mammals that includes the aerobic removal of three methyl groups from the intermediate lanosterol, one from position 14 and two from position 4. During the demethylations at position 4, a 3-ketostero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85b93caf0fa7832c811e0126a9a365d
https://doi.org/10.1016/j.biochi.2019.12.012
https://doi.org/10.1016/j.biochi.2019.12.012