Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Simonetta Geninatti Crich"'
Autor:
Miriam Mistretta, Veronica Fiorito, Anna Lucia Allocco, Giorgia Ammirata, Myriam Y. Hsu, Sabrina Digiovanni, Marzia Belicchi, Laura Napoli, Michela Ripolone, Elena Trombetta, PierLuigi Mauri, Andrea Farini, Mirella Meregalli, Chiara Villa, Paolo Ettore Porporato, Barbara Miniscalco, Simonetta Geninatti Crich, Chiara Riganti, Yvan Torrente, Emanuela Tolosano
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113854- (2024)
Summary: The definition of cell metabolic profile is essential to ensure skeletal muscle fiber heterogeneity and to achieve a proper equilibrium between the self-renewal and commitment of satellite stem cells. Heme sustains several biological functio
Externí odkaz:
https://doaj.org/article/50dee958b32b4bd7afe013a87f52d7b3
Autor:
Diego Alberti, Eric Thiaudiere, Elodie Parzy, Sabrina Elkhanoufi, Sahar Rakhshan, Rachele Stefania, Philippe Massot, Philippe Mellet, Silvio Aime, Simonetta Geninatti Crich
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract This work aims at developing a diagnostic method based on Electron Paramagnetic Resonance (EPR) measurements of stable nitroxide radicals released from “EPR silent” liposomes. The liposome destabilisation and consequent radical release i
Externí odkaz:
https://doaj.org/article/f99e01707f164aceac9e9ef835f46b45
Autor:
Nausicaa Clemente, Simona Baroni, Simone Fiorilla, Francesco Tasso, Simone Reano, Chiara Borsotti, Maria Rosaria Ruggiero, Elisa Alchera, Marco Corrazzari, Gillian Walker, Antonia Follenzi, Simonetta Geninatti Crich, Rita Carini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Pharmacological treatments for advanced hepatocellular carcinoma (HCC) have a partial efficacy. Augmented Na+ content and water retention are observed in human cancers and offer unexplored targets for anticancer therapies. Na+ levels are eva
Externí odkaz:
https://doaj.org/article/7b9e3af363b549a185401d7669fa6d39
Autor:
Jacopo Sforzi, Alberto Lanfranco, Rachele Stefania, Diego Alberti, Valeria Bitonto, Stefano Parisotto, Polyssena Renzi, Nicoletta Protti, Saverio Altieri, Annamaria Deagostino, Simonetta Geninatti Crich
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract This study aims to develop poly lactic-co-glycolic acid (PLGA) nanoparticles with an innovative imaging-guided approach based on Boron Neutron Capture Therapy for the treatment of mesothelioma. The herein-reported results demonstrate that PL
Externí odkaz:
https://doaj.org/article/9af9163bda7942a481fc3c176bca3fec
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background The combination of imaging and therapeutic agents in the same smart nanoparticle is a promising option to perform a minimally invasive imaging guided therapy. In this study, Low density lipoproteins (LDL), one of the most attracti
Externí odkaz:
https://doaj.org/article/ae258910ea114b8c822fa9d1954aa406
Autor:
Elisabetta Sieni, Simonetta Geninatti Crich, Maria Rosaria Ruggiero, Lucia Del Bianco, Federico Spizzo, Roberta Bertani, Mirto Mozzon, Marco Barozzi, Michele Forzan, Paolo Sgarbossa
Publikováno v:
Fluids, Vol 8, Iss 3, p 83 (2023)
The paper aims to compare different methods able to estimate the specific loss power (SLP) generated by three different types of magnetic nanoparticles, MNPs, dispersed in a suspension fluid, e.g., octane or water. The nanoparticles were characterize
Externí odkaz:
https://doaj.org/article/e24c23a10b8448aa90449cf3ce5c1564
Publikováno v:
ACS Omega, Vol 5, Iss 4, Pp 1764-1772 (2020)
Externí odkaz:
https://doaj.org/article/bc1021184ff0437b9d63e96d585774c5
Autor:
Maria Rosaria Ruggiero, Simona Baroni, Valeria Bitonto, Roberto Ruiu, Smeralda Rapisarda, Silvio Aime, Simonetta Geninatti Crich
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
This study aims to explore whether the water exchange rate constants in tumor cells can act as a hallmark of pathology status and a reporter of therapeutic outcomes. It has been shown, using 4T1 cell cultures and murine allografts, that an early asse
Externí odkaz:
https://doaj.org/article/e704e27b3e7d4c89a99602ff6b0019b6
Autor:
Maria Rosaria Ruggiero, Hamza Ait Itto, Simona Baroni, Sandra Pierre, Jean Boutonnat, Lionel M. Broche, Silvio Aime, François Berger, Simonetta Geninatti Crich, Hana Lahrech
Publikováno v:
Cancers, Vol 14, Iss 17, p 4180 (2022)
This work shows that the longitudinal relaxation differences observed at very low magnetic fields between invasion/migration and proliferation processes on glioma mouse models in vivo are related to differences in the transmembrane water exchange bas
Externí odkaz:
https://doaj.org/article/3232f5f3d24f4adb8e2efa0fab246356
Autor:
Antonella Nai, Maria Rosa Lidonnici, Giorgia Federico, Mariateresa Pettinato, Violante Olivari, Federica Carrillo, Simonetta Geninatti Crich, Giuliana Ferrari, Clara Camaschella, Laura Silvestri, Francesca Carlomagno
Publikováno v:
Haematologica, Vol 106, Iss 3 (2020)
The Nuclear Receptor Coactivator 4 (NCOA4) promotes ferritin degradation and Ncoa4-ko mice in C57BL/6 background show microcytosis and mild anemia, aggravated by iron deficiency. To understand tissue specific contribution of NCOA4-mediated ferritinop
Externí odkaz:
https://doaj.org/article/b4271343b7a34463b76c59669b198260