Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Simonetta Gemma"'
Autor:
Anna Maria Ingelido, Annalisa Abballe, Simonetta Gemma, Elena Dellatte, Nicola Iacovella, Giovanna De Angelis, Valentina Marra, Francesca Russo, Marina Vazzoler, Emanuela Testai, Elena De Felip
Publikováno v:
Environment International, Vol 136, Iss , Pp - (2020)
Human exposure to per- and polyfluorinated alkyl substances (PFASs) is a major public health concern because in the last decades several cases of overexposure of people to PFASs, in particular through contaminated water, occurred worldwide. In 2013
Externí odkaz:
https://doaj.org/article/5adcfdb90f174ae693197fc03cc9958b
Autor:
Simonetta Gemma, Emanuela Testai, Elena Dellatte, Giovanna De Angelis, Nicola Iacovella, Marina Vazzoler, Elena De Felip, Valentina Marra, Annalisa Abballe, Anna Maria Ingelido, Silvia Valentini, Roberto Miniero, F. Zampaglioni, Francesca Russo
Publikováno v:
Environment International, Vol 110, Iss, Pp 149-159 (2018)
BASE-Bielefeld Academic Search Engine
BASE-Bielefeld Academic Search Engine
In 2013 a contamination of drinking water by perfluoroalkylated substances (PFASs) was discovered in areas of the Veneto Region (northern Italy). In this study the exposure to PFASs of people living in the aforesaid areas was characterized: contamina
Autor:
Eugenia Dogliotti, Laura Ottini, Alessandro Filomena, Ines Zanna, Giovanna Masala, Simonetta Gemma, Giuseppe Matullo, Renato Moretti, Francesco Sera, Calogero Saieva, Alessandra Allione, Ida Luzzi, Saverio Caini, Emanuela Testai, Maria-Jesus Gomez-Miguel, Gabriella Nesi, Domenico Palli, A. Calcagnile, Silvia Polidoro, Simonetta Guarrera, Mariarosaria D’Errico
Publikováno v:
BASE-Bielefeld Academic Search Engine
Risk factors for gastric cancer (GC) include inter-individual variability in the inflammatory response to Helicobacter pylori infection, in the ability of detoxifying DNA reactive species and repairing DNA damage generated by oxidative stress and die
Autor:
Simonetta Gemma, Sven Stanzel, Annette Kopp-Schneider, J. Sandström von Tobel, Marie-Gabrielle Zurich, Florianne Monnet-Tschudi, Susanna Vichi, Emanuela Testai
Publikováno v:
Toxicology In Vitro : An International Journal Published In Association With Bibra, vol. 30, no. 1 Pt A, pp. 176-184
Within the Predict-IV FP7 project a strategy for measurement of in vitro biokinetics was developed, requiring the characterization of the cellular model used, especially regarding biotransformation, which frequently depends on cytochrome P450 (CYP) a
Publikováno v:
Environmental Toxicology and Pharmacology. 8:103-110
A comparative kinetic study in B6C3F1 mice, Osborne-Mendel (OM) and Sprague-Dawley (SD) rats has been undertaken with the major aim to determine the extent of covalent binding of chloroform reactive metabolites produced in vivo through oxidative and/
Publikováno v:
Archives of Toxicology. 73:387-393
The time course of some biochemical changes in the liver and in the kidney was studied in B6C3F1 male mice dosed with a single i.p. injection of 150 mg/kg body weight (b.w.) CHCl(3). Hepatic and renal microsomal cytochrome P450 (P450) content and som
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 13:53-61
The metabolism of diazinon, an organo-phosphorothionate pesticide, to diazoxon and pyrimidinol has been studied in incubations with hepatic microsomes from control Sprague-Dawley (SD) rats or SD rats treated with different P450-specific inducers (phe
Publikováno v:
Journal of Biochemical Toxicology. 9:305-310
The different production of phosgene and free-radicals from CHCl3 and CCl4 was determined in vitro and in vivo, by measuring the regioselective binding to the two intermediates to phospholipid (PL) molecules. Results clearly indicated that this assay
Publikováno v:
Environmental Health Perspectives
The treatment of Osborne-Mendel rats with ethanol in drinking water for 2 weeks resulted in a 3-fold increase of hepatic microsomal hydroxylation of both p-nitrophenol and aniline, two substrates considered highly selective for P4502E1. No other form
Autor:
Simonetta Gemma, Enzo Funari, Sara Bogialli, Emanuela Testai, Mara Stefanelli, Simona Scardala, Ernesto Corradetti, Maura Manganelli, Piegiorgio Ceccarelli, Daniela Mattei, Susanna Vichi, Ines Petrucci
Publikováno v:
Water research. 44(5)
Increasing concern for human health related to cyanotoxin exposure imposes the identification of pattern and level of exposure; however, current monitoring programs, based on cyanobacteria cell counts, could be inadequate. An integrated approach has