Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review

Autor: Danielle Barbosa Brotto, Ádamo Davi Diógenes Siena, Isabela Ichihara de Barros, Simone da Costa e Silva Carvalho, Bruna Rodrigues Muys, Lucas Goedert, Cibele Cardoso, Jessica Rodrigues Plaça, Anelisa Ramão, Jeremy Andrew Squire, Luiza Ferreira Araujo, Wilson Araújo da Silva

Publikováno v: Tumor Biology, Vol 42 (2020)

Homeobox genes function as master regulatory transcription factors during development, and their expression is often altered in cancer. The HOX gene family was initially studied intensively to understand how the expression of each gene was involved i

Externí odkaz: https://doaj.org/article/ed091ebde5264aefb7a51bb29eb25d49

Estudo do Papel do Gene SLC26A4 na Surdez Neurossensorial Não-Sindrômica Pré-Lingual em uma Série de Casos no Sudeste Brasileiro

Autor: Simone da Costa e Silva Carvalho

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

A audição representa a principal fonte para o aprendizado da fala e linguagem durante a infância e a surdez e a privação de estímulos auditivos pode implicar em dificuldades emocionais e sociais àqueles indivíduos afetados. Aproximadamente 36

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/17/17135/tde-28072015-121136/

Germline variants in DNA repair genes associated with hereditary breast and ovarian cancer syndrome: analysis of a 21 gene panel in the Brazilian population

Autor: Lorena Alves Texeira, Simone da Costa e Silva Carvalho, Patrícia de Cássia Ruy, Nathalia Moreno Cury, Victor Evangelista de Faria Ferraz, Wilson A. Silva, Reginaldo Cruz Alves Rosa, Danielle Barbosa Brotto, Luiza Ferreira de Araújo, Dirce Maria Carraro, Patricia Ashton-Prolla, Julio Cesar Moriguti, Edenir Inêz Palmero, Kamila Chagas Peronni, Adriana Aparecida Marques, Jessica Rodrigues Plaça, Greice Andreotti de Molfetta

Publikováno v: BMC Medical Genomics, Vol 13, Iss 1, Pp 1-24 (2020)
BMC Medical Genomics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

BackgroundThe Hereditary Breast and Ovarian Cancer Syndrome (HBOC) occurs in families with a history of breast/ovarian cancer, presenting an autosomal dominant inheritance pattern.BRCA1andBRCA2are high penetrance genes associated with an increased ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c853fb09c2bbbc4de4e3b7870a10868
https://doaj.org/article/7017c847d5db4a25b8ac154488e75410

Casein and whey protein in the breast milk ratio: could it promote protein metabolism enhancement in physically active adults?

Autor: Bryan Steve Martinez Galan, Gabriela Ferreira Abud, Julio Sérgio Marchini, Flávia Giolo De Carvalho, Gabriela Ueta Ortiz, Simone da Costa e Silva Carvalho, Juan C. Aristizabal, Camila Fernanda Cunha Brandao, Ellen Cristini de Freitas, Sara Ivone Barros Morhy Terrazas, Mônica S. S. Meirelles, Simone Sakagute

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nutrients
Volume 13
Issue 7
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Nutrients, Vol 13, Iss 2153, p 2153 (2021)

Due to the utilization of milk proteins such as whey protein (WP) and casein as sports nutrition ergogenic aids, the present study investigated the effects of the association of WP and casein in a ratio of 80:20, a similar ratio of human breast milk,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246ca44a5854d0e680f837ac805f58b8

A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor

Autor: Simone da Costa e Silva Carvalho, Mandy Ducy, Jean-Yves Masson, Giuliana De-Gregoriis, Amélie Rodrigue, Thiago T. Gomes, Gemma Montalban, Marcelo A. Carvalho, Guillaume Margaillan, Larissa Milano, Wilson A. Silva, Yan Coulombe, Graham Dellaire, Alvaro N.A. Monteiro, Jacques Simard

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nucleic Acids Research

While biallelic mutations in the PALB2 tumor suppressor cause Fanconi anemia subtype FA-N, monoallelic mutations predispose to breast and familial pancreatic cancer. Although hundreds of missense variants in PALB2 have been identified in patients to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f3dedc1277771097d81e17851ac957