Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Simone Visosky Ward"'
Publikováno v:
Human Gene Therapy. 22:1593-1598
Acute promyelocytic leukemia (APL) results from a chromosomal translocation that gives rise to the leukemogenic fusion protein PML-RARα (promyelocytic leukemia–retinoic acid α receptor). Differentiation of leukemic cells and complete remission of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa682ab8a6169e5613e6f3271f2aad61
https://doi.org/10.1089/hum.2011.079
https://doi.org/10.1089/hum.2011.079
Autor:
Simone Visosky Ward, Charles E. Samuel
Publikováno v:
Virology. 313:553-566
The protein kinase regulated by RNA (PKR) is an important mediator of the antiviral and antiproliferative actions of interferon (IFN). The promoter of the PKR gene contains a novel 15-bp element designated KCS that is required for both basal and IFN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeb9abd705d03b194616bd91b80e116
https://doi.org/10.1016/s0042-6822(03)00347-7
https://doi.org/10.1016/s0042-6822(03)00347-7
Publikováno v:
Gene. 304:143-149
The ADAR1 gene encodes an RNA-specific adenosine deaminase that alters the functional activity of both viral and cellular RNAs by posttranscriptional adenosine-to-inosine RNA editing. The interferon (IFN) responsive PI promoter of the ADAR1 gene poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289f67e0e7ec96428d0f02b2a72ad6b9
https://doi.org/10.1016/s0378-1119(02)01200-3
https://doi.org/10.1016/s0378-1119(02)01200-3
Publikováno v:
Journal of Interferon & Cytokine Research. 22:891-898
The RNA-dependent protein kinase PKR promoter is interferon (IFN) inducible and possesses a novel 15-base pair (bp) constitutive activator element, designated kinase conserved sequence (KCS), in addition to an IFN-stimulated response element (ISRE).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfcbf26d559ea771d5a95214ead81db
https://doi.org/10.1089/107999002760274917
https://doi.org/10.1089/107999002760274917
Autor:
Fermin Garduno, Jenny B. Avanzini, Simone Visosky Ward, Lily Jow, Ben Guenther, Darly J. Manayani, Jeff Alexander, Xin Dong, Victoria Snarsky, Glenn Ishioka, Mark J. Newman, Jason Mendy, Tim Mayall, Peggy Farness, Lo Vang
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31177 (2012)
PLoS ONE
PLoS ONE
Background Influenza virus remains a significant health and social concern in part because of newly emerging strains, such as avian H5N1 virus. We have developed a prototype H5N1 vaccine using a recombinant, replication-competent Adenovirus serotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64155d5be69e02a6b83f7edae587186
http://europepmc.org/articles/PMC3281928?pdf=render
http://europepmc.org/articles/PMC3281928?pdf=render
Publikováno v:
Proceedings of the National Academy of Sciences. 108
In their letter, Steinman and Wang (1) raise the possibility that p110 expression may be affected by specific gene targeting of the p150 isoform of adenosine deaminase 1 (ADAR1), similar to the concerns raised in the letter by Matthaei et al. (2). Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158dd51f52061e155a793e792a4f2bbd
https://doi.org/10.1073/pnas.1105352108
https://doi.org/10.1073/pnas.1105352108
Matthaei et al. (1) raise the possibility that specific targeting of the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 (ADAR1) may have resulted in the generation of a hypomorph of the p110 isoform, thereby generating a functional doub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e596c9cfaf3e63087ca1be5e4907ec6a
https://europepmc.org/articles/PMC3064358/
https://europepmc.org/articles/PMC3064358/
Publikováno v:
The Journal of biological chemistry. 281(6)
The protein kinase regulated by RNA (PKR) is interferon (IFN)-inducible and plays important roles in many cellular processes, including virus multiplication, cell growth, and apoptosis. The TATA-less PKR promoter possesses a novel 15-bp DNA element (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45937ddcdbc546827c1e3d2e14c11ddc
https://pubmed.ncbi.nlm.nih.gov/16339759
https://pubmed.ncbi.nlm.nih.gov/16339759
Publikováno v:
The Journal of biological chemistry. 279(8)
Protein kinase regulated by RNA (PKR) plays important roles in many cellular processes including virus multiplication and cell growth, differentiation, and apoptosis. The promoter of the PKR gene possesses a novel 15-bp element designated KCS, positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c7afccafc9281c2c7e2282bdf06426
https://pubmed.ncbi.nlm.nih.gov/14645369
https://pubmed.ncbi.nlm.nih.gov/14645369
Autor:
Charles E. Samuel, Simone Visosky Ward
Publikováno v:
Virology. (1):136-146
The RNA-dependent protein kinase PKR plays important roles in the antiviral and antiproliferative actions of IFN. The IFN-inducible promoter of the human PKR gene contains a 15-bp DNA element designated KCS. The KCS element is located 4 bp upstream o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3047390afe5dcde6bd8dfd98287c1a91