Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Simone Thomas"'
Autor:
Kathrin Hammon, Kathrin Renner, Michael Althammer, Florian Voll, Nathalie Babl, Sonja-Maria Decking, Peter J. Siska, Carina Matos, Zugey Elizabeth Cárdenas Conejo, Karina Mendes, Friederike Einwag, Heiko Siegmund, Sabine Iberl, Raffaela S. Berger, Katja Dettmer, Rebecca Schoenmehl, Christoph Brochhausen, Wolfgang Herr, Peter J. Oefner, Michael Rehli, Simone Thomas, Marina Kreutz
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
D-2-hydroxyglutarate (D-2-HG) accumulates in primary acute myeloid leukemia (AML) patients with mutated isocitrate dehydrogenase (IDH) and other malignancies. D-2-HG suppresses antitumor T cell immunity but little is known about potential effects on
Externí odkaz:
https://doaj.org/article/10b1b9a9fb744f37b8e904c18044a165
Autor:
Daniel Heudobler, Florian Luke, Joachim Hahn, Matthias Grube, Pavla Schlosser, Stephan Kremers, Thomas Sudhoff, Jorg Westermann, Marie Luise Hutter-Kronke, Richard F. Schlenk, Daniela Weber, Peter Paschka, Florian Zeman, Hartmut Dohner, Wolfgang Herr, Albrecht Reichle, Simone Thomas
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/1bb003d3eb94499faafb19a07880a180
Autor:
Simone Thomas, Hinrich Abken
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Chimeric antigen receptors (CARs) in the canonical “second generation” format provide two signals for inducing T cell effector functions; the primary “signal-1” is provided through the TCR CD3ζ chain and the “signal-2” through a linked c
Externí odkaz:
https://doaj.org/article/2e809b07e7e748199805eda69516f4e4
Publikováno v:
Journal of Rehabilitation Medicine, Vol 51, Iss 10, Pp 797-804 (2019)
Objectives: To describe physiotherapeutic interventions used in the post-acute inpatient rehabilitation of chronic critically ill patients with intensive-care-unit-acquired muscle weakness, and to determine the influence of such interventions on pati
Externí odkaz:
https://doaj.org/article/aec9bdddb05f4dc1b0d483bf24039c2c
Autor:
Steffi Krauter, Nicole Büscher, Eric Bräuchle, Samira Ortega Iannazzo, Inessa Penner, Nadine Krämer, Patricia Gogesch, Simone Thomas, Marina Kreutz, Mario Dejung, Anja Freiwald, Falk Butter, Zoe Waibler, Bodo Plachter
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1326 (2022)
Human cytomegalovirus (HCMV) infection is associated with severe disease conditions either following congenital transmission of the virus or viral reactivation in immunosuppressed individuals. Consequently, the establishment of a protective vaccine i
Externí odkaz:
https://doaj.org/article/6b6f8b31f9634f6887338cdd87f2d9e4
Autor:
Sebastian Klobuch, Kathrin Hammon, Sarah Vatter-Leising, Elisabeth Neidlinger, Michael Zwerger, Annika Wandel, Laura Maria Neuber, Bernhard Heilmeier, Regina Fichtner, Carina Mirbeth, Wolfgang Herr, Simone Thomas
Publikováno v:
Cells, Vol 9, Iss 5, p 1264 (2020)
HLA-DPB1 antigens are mismatched in about 80% of allogeneic hematopoietic stem cell transplantations from HLA 10/10 matched unrelated donors and were shown to be associated with a decreased risk of leukemia relapse. We recently developed a reliable i
Externí odkaz:
https://doaj.org/article/ce18501a9a5b4c9883231bf94d436596
Autor:
Kathrin Renner, Anton Seilbeck, Nathalie Kauer, Ines Ugele, Peter J. Siska, Christina Brummer, Christina Bruss, Sonja-Maria Decking, Matthias Fante, Astrid Schmidt, Kathrin Hammon, Katrin Singer, Sebastian Klobuch, Simone Thomas, Eva Gottfried, Katrin Peter, Marina Kreutz
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The accelerated metabolism of tumor cells, inevitable for maintaining high proliferation rates, is an emerging target for tumor therapy. Increased glucose and lipid metabolism as well as mitochondrial activity have been shown in solid tumors but also
Externí odkaz:
https://doaj.org/article/2a068e5a9f344f869bc511d67dced0cf
Autor:
Daniel Heudobler, Sebastian Klobuch, Simone Thomas, Joachim Hahn, Wolfgang Herr, Albrecht Reichle
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cutaneous manifestations in hematologic malignancies, especially in leukemia, are not common and may be very variable. Here we report a very unusual case of a patient (female, 70 years old) who was admitted to the hospital in 2016 because of skin les
Externí odkaz:
https://doaj.org/article/18fcbdfa17a447bd958bd65af13fe5ae
Autor:
Sebastian Klobuch, Tim Steinberg, Emanuele Bruni, Carina Mirbeth, Bernhard Heilmeier, Lina Ghibelli, Wolfgang Herr, Albrecht Reichle, Simone Thomas
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Effective and tolerable salvage therapies for elderly patients with chemorefractory acute myeloid leukemia (AML) are limited and usually do not change the poor clinical outcome. We recently described in several chemorefractory elderly AML patients th
Externí odkaz:
https://doaj.org/article/6c5083509dd9422c957961b7a722d8bb
Autor:
Daniel Heudobler, Michael Rechenmacher, Florian Lüke, Martin Vogelhuber, Sebastian Klobuch, Simone Thomas, Tobias Pukrop, Christina Hackl, Wolfgang Herr, Lina Ghibelli, Christopher Gerner, Albrecht Reichle
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Classic tumor therapy, consisting of cytotoxic agents and/or targeted therapy, has not overcome therapeutic limitations like poor risk genetic parameters, genetic heterogeneity at different metastatic sites or the problem of undruggable targets. Here
Externí odkaz:
https://doaj.org/article/72d0ff918c3d4ff29148b154b8cef4b4