Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Simone Tamburri"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/4155fedc60ed45859cd88add9954e5a5
Publikováno v:
Trends in Genetics. 38:333-352
Cell identity is tightly controlled by specific transcriptional programs which require post-translational modifications of histones. These histone modifications allow the establishment and maintenance of active and repressed chromatin domains. Histon
Autor:
Jonathan F. Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L. Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M. Burg, Allison R. Hickman, Lu Sun, Saarang Gopinath, Hailey Taylor, Matthew J. Meiners, Marcus A. Cheek, William Rice, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache
Publikováno v:
bioRxiv
The maintenance of gene expression patterns during metazoan development is achieved by the actions of Polycomb group (PcG) complexes. An essential modification marking silenced genes is monoubiquitination of histone H2A lysine 119 (H2AK119Ub) deposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db25e4b2a5a80a0e97a9d5d66c694d3
https://doi.org/10.1101/2023.02.23.529554
https://doi.org/10.1101/2023.02.23.529554
Autor:
Simone Tamburri, Eleonora Ponzo, Federico Rossi, Marika Zanotti, Simona Rodighiero, Diego Pasini, Daria Manganaro, Karin Johanna Ferrari, Daniel Fernández-Pérez, Eric Conway
Publikováno v:
Molecular Cell
Summary BAP1 is mutated or deleted in many cancer types, including mesothelioma, uveal melanoma, and cholangiocarcinoma. It is the catalytic subunit of the PR-DUB complex, which removes PRC1-mediated H2AK119ub1, essential for maintaining transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed4cfe3006157ef0b911f7e9c253c92
https://hdl.handle.net/2434/946749
https://hdl.handle.net/2434/946749
Autor:
Giovanna Musco, Chiara Zucchelli, Giacomo Quilici, Giuseppe Filosa, Angela Bachi, Michela Ghitti, Simone Tamburri
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1863:456-465
Background Human Sp140 protein is a leukocyte-specific member of the speckled protein (Sp) family (Sp100, Sp110, Sp140, Sp140L), a class of multi-domain nuclear proteins involved in intrinsic immunity and transcriptional regulation. Sp140 regulates m
Autor:
Pasquale Conforti, Karin Johanna Ferrari, Tiziana Bonaldi, Marika Zanotti, Daniel Fernández-Pérez, Cecilia Toscani, Diego Pasini, Roberta Noberini, Alessandra Rossi, Simona Amato, Simone Tamburri
Publikováno v:
Nucleic Acids Research
The proteolytic cleavage of histone tails, also termed histone clipping, has been described as a mechanism for permanent removal of post-translational modifications (PTMs) from histone proteins. Such activity has been ascribed to ensure regulatory fu
Autor:
Eric Conway, Federico Rossi, Daria Manganaro, Diego Pasini, Karin Johanna Ferrari, Simona Rodighiero, Simone Tamburri, Ponzo E, Marika Zanotti, Daniel Fernández-Pérez
BAP1 is recurrently mutated or deleted in a large number of diverse cancer types, including mesothelioma, uveal melanoma and hepatocellular cholangiocarcinoma. BAP1 is the catalytic subunit of the Polycomb Repressive De-Ubiquitination complex (PR-DUB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00bee35bc4a48cc93dc4363c7e0d1299
https://doi.org/10.1101/2020.12.10.419309
https://doi.org/10.1101/2020.12.10.419309
Autor:
Francesco Blasi, Valentina De Lorenzi, Simone Tamburri, Menotti Ruvo, Alessandra Monti, Angela Bachi, Lisa Mathiasen, Angela Cattaneo, Nunzianna Doti, Chiara Bruckmann
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Both onco-suppressor PREP1 and the oncogene MEIS1 bind to PBX1. This interaction stabilizes the two proteins and allows their translocation into the nucleus and thus their transcriptional activity. Here, we have combined cross-linking mass-spectromet
Autor:
Francesco Farris, Vittoria Matafora, Angela Bachi, Simone Tamburri, Silvia Marsoni, Umberto Restuccia, Luca Lazzari, Giuseppe Martano, Clara Bernardelli, Federica Pisati, Andrea Sofia, Francesca Casagrande, Emanuela Bonoldi
Publikováno v:
EMBO Reports
Melanoma progression is generally associated with increased transcriptional activity mediated by the Yes‐associated protein (YAP). Mechanical signals from the extracellular matrix are sensed by YAP, which then activates the expression of proliferat
Autor:
Silvia Marsoni, Federica Pisati, Angela Bachi, Luca Lazzari, Umberto Restuccia, Vittoria Matafora, Francesca Casagrande, Francesco Farris, Simone Tamburri, Clara Bernardelli, Emanuela Bonoldi, Giuseppe Martano
Melanoma progression is generally associated to increased Yes-associated protein (YAP) mediated transcription. Actually, mechanical signals from the extracellular matrix are sensed by YAP, which activates proliferative genes expression, promoting mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3424326be865774d2feccfa49ad6cc1