Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Simone Spolaor"'
Publikováno v:
Advanced Science, Vol 11, Iss 27, Pp n/a-n/a (2024)
Abstract Accurate glucose prediction is vital for diabetes management. Artificial intelligence and artificial neural networks (ANNs) are showing promising results for reliable glucose predictions, offering timely warnings for glucose fluctuations. Th
Externí odkaz:
https://doaj.org/article/0f49eadf21524f6186c9cb665535cd50
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011700 (2023)
Fuzzy logic is useful tool to describe and represent biological or medical scenarios, where often states and outcomes are not only completely true or completely false, but rather partially true or partially false. Despite its usefulness and spread, f
Externí odkaz:
https://doaj.org/article/0cab8ae880e549149ffdc99200bb8537
Autor:
Daniele M. Papetti, Simone Spolaor, Iman Nazari, Andrea Tirelli, Tommaso Leonardi, Chiara Caprioli, Daniela Besozzi, Thalia Vlachou, Pier Giuseppe Pelicci, Paolo Cazzaniga, Marco S. Nobile
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Introduction: Oxford Nanopore Technologies (ONT) is a third generation sequencing approach that allows the analysis of individual, full-length nucleic acids. ONT records the alterations of an ionic current flowing across a nano-scaled pore while a DN
Externí odkaz:
https://doaj.org/article/cfc4ec53880f413b8dcbb9ba447a63aa
Autor:
Amalia Lupi, Simone Spolaor, Alessandro Favero, Luca Bello, Roberto Stramare, Elena Pegoraro, Marco Salvatore Nobile
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285422 (2023)
PurposeCongenital myopathies are a heterogeneous group of diseases affecting the skeletal muscles and characterized by high clinical, genetic, and histological variability. Magnetic Resonance (MR) is a valuable tool for the assessment of involved mus
Externí odkaz:
https://doaj.org/article/d12997091eb74309bf6d538adccbf664
Autor:
Simone Spolaor, Mattia Rovetta, Marco S. Nobile, Paolo Cazzaniga, Renata Tisi, Daniela Besozzi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Calcium homeostasis and signaling processes in Saccharomyces cerevisiae, as well as in any eukaryotic organism, depend on various transporters and channels located on both the plasma and intracellular membranes. The activity of these proteins is regu
Externí odkaz:
https://doaj.org/article/bfc503a204064324b7205f598026ea16
Autor:
Andrea Tangherloni, Marco S Nobile, Paolo Cazzaniga, Giulia Capitoli, Simone Spolaor, Leonardo Rundo, Giancarlo Mauri, Daniela Besozzi
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009410 (2021)
Mathematical models of biochemical networks can largely facilitate the comprehension of the mechanisms at the basis of cellular processes, as well as the formulation of hypotheses that can be tested by means of targeted laboratory experiments. Howeve
Externí odkaz:
https://doaj.org/article/c68e42988e454d1fb93c38388c684beb
Autor:
Andrea Tangherloni, Simone Spolaor, Leonardo Rundo, Marco S. Nobile, Paolo Cazzaniga, Giancarlo Mauri, Pietro Liò, Ivan Merelli, Daniela Besozzi
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S4, Pp 1-14 (2019)
Abstract Background In order to fully characterize the genome of an individual, the reconstruction of the two distinct copies of each chromosome, called haplotypes, is essential. The computational problem of inferring the full haplotype of a cell sta
Externí odkaz:
https://doaj.org/article/3a3fab37dad84b53af785205d792e540
Shaping and Dilating the Fitness Landscape for Parameter Estimation in Stochastic Biochemical Models
Publikováno v:
Applied Sciences, Vol 12, Iss 13, p 6671 (2022)
The parameter estimation (PE) of biochemical reactions is one of the most challenging tasks in systems biology given the pivotal role of these kinetic constants in driving the behavior of biochemical systems. PE is a non-convex, multi-modal, and non-
Externí odkaz:
https://doaj.org/article/f0b845eff4be4fab8d1541a2babd98fe
Autor:
Simone Spolaor, Martijn Scheve, Murat Firat, Paolo Cazzaniga, Daniela Besozzi, Marco S. Nobile
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Combination therapies proved to be a valuable strategy in the fight against cancer, thanks to their increased efficacy in inducing tumor cell death and in reducing tumor growth, metastatic potential, and the risk of developing drug resistance. The id
Externí odkaz:
https://doaj.org/article/0118642e6e9a4993804e5e12df8d1e1a
Publikováno v:
International Journal of Computational Intelligence Systems, Vol 13, Iss 1 (2020)
Many researchers have used fuzzy set theory and fuzzy logic in a variety of applications related to computer science and engineering, given the capability of fuzzy inference systems to deal with uncertainty, represent vague concepts, and connect huma
Externí odkaz:
https://doaj.org/article/f52a1bcc701d460e9b5ac32042d2e102