Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Simone Sharma"'
Publikováno v:
International Journal of Engineering Applied Sciences and Technology. :310-316
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdd9dd342632f11a625988a155948e81
https://doi.org/10.33564/ijeast.2020.v04i12.054
https://doi.org/10.33564/ijeast.2020.v04i12.054
Autor:
Ravindran Kumaran, Jana Vandrovcova, Connie Luk, Simone Sharma, Alan Renton, Nicholas W. Wood, John A. Hardy, Andrew J. Lees, Rina Bandopadhyay
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 393-400 (2009)
Mutations in the DJ-1 gene have been linked with rare cases of early onset, autosomal recessive Parkinson's disease (PD). To determine whether DJ-1 is also involved in the pathogenesis of common forms of PD we have compared DJ-1 mRNA levels in a numb
Externí odkaz:
https://doaj.org/article/6cd1c5c7876946fd8f3d1e81fa693e8e
Publikováno v:
The Journal of Immunology. 193:3538-3548
HIV-1 causes a progressive impairment of immune function. HIV-2 is a naturally attenuated form of HIV, and HIV-2 patients display a slow-progressing disease. The leading hypothesis for the difference in disease phenotype between HIV-1 and HIV-2 is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33470376f3ed34670d04099208ab983f
https://doi.org/10.4049/jimmunol.1400860
https://doi.org/10.4049/jimmunol.1400860
Autor:
Ann E. Kingsbury, Janice L. Holton, Alan E. Renton, Sean S. O'Sullivan, Carles Vilariño-Güell, Nicholas W. Wood, Simone Sharma, Tamas Revesz, R. Kumaran, Rina Bandopadhyay, Tammaryn Lashley, Andrew J. Lees, Constantinos Kallis
Publikováno v:
Neuropathology and Applied Neurobiology. 37:777-790
Aims: Mutations in the gene encoding leucine-rich repeat kinase-2 (LRRK2) have been established as a common genetic cause of Parkinson's disease (PD). The distribution of LRRK2 mRNA and protein in the human brain has previously been described, althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cfbe53d74a6358f23be1709a270aec7
https://doi.org/10.1111/j.1365-2990.2011.01187.x
https://doi.org/10.1111/j.1365-2990.2011.01187.x
Autor:
Masato Hasegawa, S. A. Simpson, Takashi Nonaka, Julie S. Snowden, David M. A. Mann, J. W. Moore, Stuart Pickering-Brown, T Revesz, M. Hutton, Kenji Ikeda, Simone Sharma, Marianne Baker, James MacKenzie, R de Silva
Publikováno v:
Brain. 127:1415-1426
In this report, we describe the clinical and neuropathological features of a case of familial frontotemporal dementia (FTD), with onset at 58 years of age and disease duration of 10 years, associated with a novel mutation, Q336R, in the tau gene (tau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbfdf2670756e740950075964519946
https://doi.org/10.1093/brain/awh147
https://doi.org/10.1093/brain/awh147
Autor:
Franziska, Denk, Wenlong, Huang, Ben, Sidders, Angela, Bithell, Megan, Crow, John, Grist, Simone, Sharma, Daniel, Ziemek, Andrew S C, Rice, Noel J, Buckley, Stephen B, McMahon
Publikováno v:
Pain
Summary Intrathecal delivery of histone deacetylase inhibitors ameliorates hypersensitivity in models of neuropathic pain. This effect may be mediated at the level of the spinal cord through inhibition of HDAC1 function.
Histone deacetylase inhi
Histone deacetylase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ffbe17a0dfde279def17553568e9f88
https://pubmed.ncbi.nlm.nih.gov/23693161
https://pubmed.ncbi.nlm.nih.gov/23693161
Autor:
Connie Luk, Nicholas W. Wood, Simone Sharma, John Hardy, Ravindran Kumaran, Alan E. Renton, Andrew J. Lees, Jana Vandrovcova, Rina Bandopadhyay
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 393-400 (2009)
Mutations in the DJ-1 gene have been linked with rare cases of early onset, autosomal recessive Parkinson's disease (PD). To determine whether DJ-1 is also involved in the pathogenesis of common forms of PD we have compared DJ-1 mRNA levels in a numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e01a871d1112cbc7c4674edec4e517c
https://pubmed.ncbi.nlm.nih.gov/19716892
https://pubmed.ncbi.nlm.nih.gov/19716892
Autor:
Peter Teismann, Valentina Fedele, Kristina Klupsch, P East, Alastair Morrison, Julian Downward, Nicoleta Moisoi, Alan E. Renton, R E Edwards, Mauro Degli Esposti, Nicholas W. Wood, Simone Sharma, Helene Plun-Favreau, L M Martins
Publikováno v:
Cell death and differentiation. 16(3)
Cellular stress responses can be activated following functional defects in organelles such as mitochondria and the endoplasmic reticulum. Mitochondrial dysfunction caused by loss of the serine protease HtrA2 leads to a progressive movement disorder i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab0790927a7e0185522679cd2ba4beb
https://pubmed.ncbi.nlm.nih.gov/19023330
https://pubmed.ncbi.nlm.nih.gov/19023330
Autor:
Patricia J. Moore, Simone Sharma
Publikováno v:
Evolutiondevelopment. 7(3)
Summary Women who delay childbearing risk subfertility. However, this loss of fertility is not a simple function of aging. Women who have had children early in life tend to maintain fertility longer, measured as a later age at menopause. But why shou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78edae1d79b35dd7732f8cee824834b1
https://pubmed.ncbi.nlm.nih.gov/15876194
https://pubmed.ncbi.nlm.nih.gov/15876194
Autor:
Abdullah, Hasanen S.1 nada.h.ali@uotechnology.edu.iq, Ali, Nada Hussain1, Abdullah, Nada A. Z.2
Publikováno v:
Iraqi Journal of Science. 2024, Vol. 65 Issue 3, p1741-1751. 11p.