Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Simone Schiemann"'
Publikováno v:
Analytical Biochemistry. 427:82-90
Because tumors and other diseases are characterized by increased heparanase levels, human heparanase is a promising drug target and diagnostic marker. Therefore, methods are needed to determine heparanase activity and to examine potential inhibitors.
Publikováno v:
Analytical and bioanalytical chemistry. 399(2)
There are several methods for sensitive detection of oversulfated chondroitin sulfate (OSCS) in heparin. Although contamination with OSCS is unlikely to be repeated, use of other compounds to counterfeit heparin must be considered. We have previously
Autor:
Susanne Lühn, Susanne Alban, Knut Baumann, Claudia Schilling, Simone Schiemann, Bernhard Wolf, Magnus Matz, Ulrike Holzgrabe, Tanja Beyer, Oliver Rädler, Jochen Norwig
Publikováno v:
Analytical and bioanalytical chemistry. 399(2)
The widespread occurrence of heparin contaminated with oversulfated chrondroitin sulfate (OSCS) in 2008 initiated a comprehensive revision process of the Pharmacopoeial heparin monographs and stimulated research in analytical techniques for the quali
Publikováno v:
Analytical and bioanalytical chemistry. 399(2)
In 2008, heparin contaminated with oversulfated chondroitin sulfate (OSCS) penetrated the worldwide market and was associated with severe adverse effects. Feasible and reliable methods to test heparin for adulteration are needed. The objective was to
Publikováno v:
Analytical and Bioanalytical Chemistry. 399:1393-1393