Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Simone Reano"'
Autor:
Nausicaa Clemente, Simona Baroni, Simone Fiorilla, Francesco Tasso, Simone Reano, Chiara Borsotti, Maria Rosaria Ruggiero, Elisa Alchera, Marco Corrazzari, Gillian Walker, Antonia Follenzi, Simonetta Geninatti Crich, Rita Carini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Pharmacological treatments for advanced hepatocellular carcinoma (HCC) have a partial efficacy. Augmented Na+ content and water retention are observed in human cancers and offer unexplored targets for anticancer therapies. Na+ levels are eva
Externí odkaz:
https://doaj.org/article/7b9e3af363b549a185401d7669fa6d39
Autor:
Giulia Ronchi, Pierluigi Tos, Elia Angelino, Luisa Muratori, Simone Reano, Nicoletta Filigheddu, Andrea Graziani, Stefano Geuna, Stefania Raimondo
Publikováno v:
European Journal of Histochemistry, Vol 65, Iss s1 (2021)
Ghrelin is a circulating peptide hormone released by enteroendocrine cells of the gastrointestinal tract as two forms, acylated and unacylated. Acylated ghrelin (AG) binds to the growth hormone secretagogue receptor 1a (GHSR1a), thus stimulating food
Externí odkaz:
https://doaj.org/article/38f9f3c4b50e4b2c8ed66a6f0ef0b4dd
Autor:
Annamaria Antona, Marco Varalda, Konkonika Roy, Francesco Favero, Eleonora Mazzucco, Miriam Zuccalà, Giovanni Leo, Giulia Soggia, Valentina Bettio, Martina Tosi, Miriam Gaggianesi, Beatrice Riva, Simone Reano, Armando Genazzani, Marcello Manfredi, Giorgio Stassi, Davide Corà, Sandra D’Alfonso, Daniela Capello
Publikováno v:
Cancers, Vol 14, Iss 3, p 776 (2022)
Approximately 50% of colorectal cancer (CRC) patients still die from recurrence and metastatic disease, highlighting the need for novel therapeutic strategies. Drug repurposing is attracting increasing attention because, compared to traditional de no
Externí odkaz:
https://doaj.org/article/dab999ddb7914de99929d8bc054414da
Autor:
Tommaso Raiteri, Ivan Zaggia, Simone Reano, Andrea Scircoli, Laura Salvadori, Flavia Prodam, Nicoletta Filigheddu
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1980 (2021)
Dysfunctional mitochondrial metabolism has been linked to skeletal muscle loss in several physio-pathological states. Although it has been reported that vitamin D (VD) supports cellular redox homeostasis by maintaining normal mitochondrial functions,
Externí odkaz:
https://doaj.org/article/bb78708d7de94605b295157c778ab336
Autor:
Celia Cordero-Sanchez, Beatrice Riva, Simone Reano, Nausicaa Clemente, Ivan Zaggia, Federico A. Ruffinatti, Alberto Potenzieri, Tracey Pirali, Salvatore Raffa, Sabina Sangaletti, Mario P. Colombo, Alessandra Bertoni, Matteo Garibaldi, Nicoletta Filigheddu, Armando A. Genazzani
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 2 (2020)
STIM and ORAI proteins play a fundamental role in calcium signaling, allowing for calcium influx through the plasma membrane upon depletion of intracellular stores, in a process known as store-operated Ca2+ entry. Point mutations that lead to gain-of
Externí odkaz:
https://doaj.org/article/611ada2e98354ec2808456437d74eab1
Autor:
Elia Angelino, Simone Reano, Michele Ferrara, Emanuela Agosti, Hana Sustova, Valeria Malacarne, Sara Clerici, Andrea Graziani, Nicoletta Filigheddu
Publikováno v:
Bio-Protocol, Vol 8, Iss 2 (2018)
Satellite cell (SC) transplantation represents a powerful strategy to investigate SC biology during muscle regeneration. We described here a protocol for SC isolation from green fluorescent protein (GFP)-expressing mice and their transplantation into
Externí odkaz:
https://doaj.org/article/babb925b66e74e24be77f934a092493b
Autor:
Francesca Oltolina, Andrea Zamperone, Donato Colangelo, Luca Gregoletto, Simone Reano, Stefano Pietronave, Simone Merlin, Maria Talmon, Eugenio Novelli, Marco Diena, Carmine Nicoletti, Antonio Musarò, Nicoletta Filigheddu, Antonia Follenzi, Maria Prat
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141632 (2015)
Externí odkaz:
https://doaj.org/article/472113c6ed77489685675cdcfa747374
Autor:
Elia Angelino, Simone Reano, Michele Ferrara, Emanuela Agosti, Andrea Graziani, Nicoletta Filigheddu
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Fibrosis can affect almost all tissues and organs, it often represents the terminal stage of chronic diseases, and it is regarded as a major health issue for which efficient therapies are needed. Tissue injury, by inducing necrosis/apoptosis, trigger
Externí odkaz:
https://doaj.org/article/39e656581fa14d888d62e69e16cfa5f4
Autor:
Francesca Oltolina, Andrea Zamperone, Donato Colangelo, Luca Gregoletto, Simone Reano, Stefano Pietronave, Simone Merlin, Maria Talmon, Eugenio Novelli, Marco Diena, Carmine Nicoletti, Antonio Musarò, Nicoletta Filigheddu, Antonia Follenzi, Maria Prat
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137999 (2015)
A major obstacle to an effective myocardium stem cell therapy has always been the delivery and survival of implanted stem cells in the heart. Better engraftment can be achieved if cells are administered as cell aggregates, which maintain their extra-
Externí odkaz:
https://doaj.org/article/2224d588b376464e80bba0f141f76867
Autor:
Sara Ruga, Marilisa De Feudis, Flavia Prodam, Claudio Molinari, Ivan Zaggia, Maraiza Alves Teixeira, Paolo Marzullo, Davide Corà, Nicoletta Filigheddu, Andrea Scircoli, Laura Salvadori, Tommaso Raiteri, Simone Reano
Publikováno v:
Aging (Albany NY)
We previously determined that different vitamin D metabolites can have opposite effects on C2C12 myotubes, depending on the sites of hydroxylation or doses. Specifically, 25(OH)D3 (25VD) has an anti-atrophic activity, 1,25(OH)2D3 induces atrophy, and