Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Simone P. Sittig"'
Publikováno v:
Biomedicines, Vol 3, Iss 4, Pp 282-303 (2015)
Dendritic cell (DC)-based cancer vaccines hold the great promise of tipping the balance from tolerance of the tumor to rejection. In the last two decades, we have gained tremendous knowledge about DC-based cancer vaccines. The maturation of DCs has p
Externí odkaz:
https://doaj.org/article/92e46d4434f84b9abaaf03da519a12ff
Autor:
Simone P. Sittig, Ghaith Bakdash, Jorieke Weiden, Annette E. Sköld, Jurjen Tel, Carl G. Figdor, I. Jolanda M. de Vries, Gerty Schreibelt
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Dendritic cells (DCs) are central players of immune responses; they become activated upon infection or inflammation and migrate to lymph nodes, where they can initiate an antigen-specific immune response by activating naive T cells. Two major types o
Externí odkaz:
https://doaj.org/article/a3655d0b38aa4ebb8baf018d34b1a8b5
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Evelien L. Smits, Christoph Schröder, Tjitske Duiveman-de Boer, Ruurd Torensma, Simone P. Sittig, Gerty Schreibelt, Annette E. Sköld, Stanleyson V. Hato, Altuna Halilovic, Mark A.J. Gorris, Sonja I. Buschow, Ghaith Bakdash
The gating strategy applied to isolate and determine the frequency of BDCA1+ DCs, BDCA1+ CD14+ cells, monocytes and MDSCs from PBMCS of melanoma patients or healthy donors by FACS (S1); The distribution of potentially "missed genes" over the RPKM val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76be5ea82aa72def3b1201e320c64fce
https://doi.org/10.1158/0008-5472.22409060
https://doi.org/10.1158/0008-5472.22409060
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Evelien L. Smits, Christoph Schröder, Tjitske Duiveman-de Boer, Ruurd Torensma, Simone P. Sittig, Gerty Schreibelt, Annette E. Sköld, Stanleyson V. Hato, Altuna Halilovic, Mark A.J. Gorris, Sonja I. Buschow, Ghaith Bakdash
The detailed composition of all gene sets used in GSEA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8626e51d068ac8080aa662b60916b22
https://doi.org/10.1158/0008-5472.22409063
https://doi.org/10.1158/0008-5472.22409063
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Evelien L. Smits, Christoph Schröder, Tjitske Duiveman-de Boer, Ruurd Torensma, Simone P. Sittig, Gerty Schreibelt, Annette E. Sköld, Stanleyson V. Hato, Altuna Halilovic, Mark A.J. Gorris, Sonja I. Buschow, Ghaith Bakdash
The tumor microenvironment is characterized by regulatory T cells, type II macrophages, myeloid-derived suppressor cells, and other immunosuppressive cells that promote malignant progression. Here we report the identification of a novel BDCA1+CD14+ p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e679dae9c4aaa351965e21d4a774c9
https://doi.org/10.1158/0008-5472.c.6507674.v1
https://doi.org/10.1158/0008-5472.c.6507674.v1
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Evelien L. Smits, Christoph Schröder, Tjitske Duiveman-de Boer, Ruurd Torensma, Simone P. Sittig, Gerty Schreibelt, Annette E. Sköld, Stanleyson V. Hato, Altuna Halilovic, Mark A.J. Gorris, Sonja I. Buschow, Ghaith Bakdash
GSEA raw data generated by Bubble GUM software.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc137de3b2967ed858ff22ff7fe80cd
https://doi.org/10.1158/0008-5472.22409054.v1
https://doi.org/10.1158/0008-5472.22409054.v1
Autor:
I. Jolanda M. de Vries, Carl G. Figdor, Evelien L. Smits, Christoph Schröder, Tjitske Duiveman-de Boer, Ruurd Torensma, Simone P. Sittig, Gerty Schreibelt, Annette E. Sköld, Stanleyson V. Hato, Altuna Halilovic, Mark A.J. Gorris, Sonja I. Buschow, Ghaith Bakdash
Legends for Supplementary Tables S1-S2 and Supplementary Figures S1-S12.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928fac62dbf491c7b0c266f2bb31691e
https://doi.org/10.1158/0008-5472.22409051.v1
https://doi.org/10.1158/0008-5472.22409051.v1
Autor:
Sonja I. Buschow, Johannes Textor, Jorieke Weiden, Carl G. Figdor, Georgina Flórez-Grau, Gerty Schreibelt, P. Ben H. Geurtz, I. Jolanda M. de Vries, Marcel M. Verbeek, Jasper J. P. van Beek, Mirjam C van der Net, Rianne van Slooten, Simone P. Sittig
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 51(6), 1494-1504. Wiley-VCH
European Journal of Immunology, 51, 1494-1504
European Journal of Immunology, 51, 6, pp. 1494-1504
European Journal of Immunology, 51(6), 1494-1504. Wiley-VCH
European Journal of Immunology, 51, 1494-1504
European Journal of Immunology, 51, 6, pp. 1494-1504
Dendritic cells (DCs) are key regulators of the immune system that shape T cell responses. Regulation of T cell induction by DCs may occur via the intracellular enzyme indoleamine 2,3‐dioxygenase 1 (IDO), which catalyzes conversion of the essential
Autor:
Gerty Schreibelt, Georgina Flórez-Grau, P. Ben H. Geurtz, Carl G. Figdor, Jorieke Weiden, Jasper J. P. van Beek, Sonja I. Buschow, Rianne van Slooten, Johannes Textor, Marcel M. Verbeek, Simone P. Sittig, I. Jolanda M. de Vries, Mirjam C van der Net
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d1c4b0ee50e4e3b7eae4d8179cb352
https://doi.org/10.1002/eji.202048580/v2/response1
https://doi.org/10.1002/eji.202048580/v2/response1
Autor:
Georgina Flórez-Grau, Michelle D. van den Beukel, Gerty Schreibelt, Jasper J. P. van Beek, I. Jolanda M. de Vries, Annette E. Sköld, Florian Wimmers, Simone P. Sittig, Ghaith Bakdash, Till S.M. Mathan
Publikováno v:
Cancer Immunology, Immunotherapy
Cancer Immunology Immunotherapy, 67, 1425-1436
Cancer Immunology Immunotherapy, 67, 9, pp. 1425-1436
Cancer Immunology Immunotherapy, 67, 1425-1436
Cancer Immunology Immunotherapy, 67, 9, pp. 1425-1436
There has recently been a paradigm shift in the field of dendritic cell (DC)-based immunotherapy, where several clinical studies have confirmed the feasibility and advantageousness of using directly isolated human blood-derived DCs over in vitro diff