Výsledky vyhledávání - "Simone Napieralski"

A phase II study of alemtuzumab, fludarabine, cyclophosphamide, and doxorubicin (Campath-FCD) in peripheral T-cell lymphomas

Autor: Elke Jäger, Eckhart Weidmann, Marion Subklewe, Martin Soekler, Judith Kruse, Stefan W. Krause, Martin Dreyling, Soo-Zin Kim, Paris S. Mitrou, Jürgen Rech, Kai U. Chow, Simone Napieralski, Katja Weisel, Georg Hess

Publikováno v: Leukemia & Lymphoma. 51:447-455

The clinical course of peripheral T-cell lymphoma (PTCL) is usually aggressive and the prognosis unfavorable. Therefore, there is a need for improvement of treatment options. Patients with newly diagnosed (n = 27) or refractory/relapsed (n = 11) PTCL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11438e0006702bdb8c6c950d9b0c38f7
https://doi.org/10.3109/10428190903580402

Zobrazit plný text záznamu

Plný text ve formátu HTML

In AML Cell Lines Ara-C Combined with Purine Analogues is Able to Exert Synergistic as Well as Antagonistic Effects on Proliferation, Apoptosis and Disruption of Mitochondrial Membrane Potential

Autor: Paris S. Mitrou, Simone Boehrer, Dieter Hoelzer, Simone Napieralski, Eckhart Weidmann, Andrea Knau, Kai U Chow, Daniel Nowak

Publikováno v: Leukemia & Lymphoma. 44:165-173

The pyrimidine analogue Ara-C and the purine analogues fludarabine and cladribine (2-CdA) are essential compounds in the treatment of acute myeloid leukemia (AML). Inhibition of cell proliferation and induction of apoptosis are the major mechanisms o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a43932b1708ef24faf877b46e266891
https://doi.org/10.1080/1042819021000054670

Zobrazit plný text záznamu

Induction of apoptosis using 2′,2′difluorodeoxycytidine (gemcitabine) in combination with antimetabolites or anthracyclines on malignant lymphatic and myeloid cells. Antagonism or synergism depends on incubation schedule and origin of neoplastic cells

Autor: Eckhart Weidmann, Dieter Hoelzer, Simone Boehrer, M. Stieler, F. Pourebrahim, Jürgen Ries, Paris S. Mitrou, Kai Uwe Chow, Mathias J. Rummel, Jürgen Stein, Simone Napieralski

Publikováno v: Annals of Hematology. 79:485-492

Induction of apoptosis in vitro using gemcitabine (dFdC) in combination with cladribine (2-CdA) and other cytotoxic drugs on malignant mononuclear cells (MNCs) of patients with acute myeloid leukemia (AML, n=20) and chronic lymphocytic leukemia (CLL,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66370499b6286f3f53c807a30337a149
https://doi.org/10.1007/s002770000181

Zobrazit plný text záznamu

Induction of apoptosis by 2-chloro-2'deoxyadenosine (2-CdA) alone and in combination with other cytotoxic drugs: synergistic effects on normal and neoplastic lymphocytes by addition of doxorubicin and mitoxantrone

Autor: Eckhart Weidmann, Hans Martin, Mathias J. Rummel, Petra Jantschke, Dieter Hoelzer, Paris S. Mitrou, Farsad Pourebrahim, Juergen Stein, Simone Boehrer, Simone Napieralski, Juergen Ries, Kai U Chow

Publikováno v: Leukemialymphoma. 36(5-6)

2-CdA is active as a single agent in the treatment of low-grade lymphomas. We analyzed the induction of apoptosis by 2-CdA alone (n=5) and in combination with other drugs in peripheral lymphocytes from 25 patients with leukemic low-grade lymphomas an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1850d56f5c28a7929eed6460c8e365c6
https://pubmed.ncbi.nlm.nih.gov/10784401

Zobrazit plný text záznamu

Plný text ve formátu HTML

Sustained Molecular Responses with Interferon α2a Maintenance Therapy after Imatinib Plus IFN Induction Treatment for Chronic Phase Chronic Myelogenous Leukemia

Autor: Andreas Burchert, Andreas Neubauer, Martin C. Mueller, Andreas Hochhaus, Simone Napieralski, Ruediger Hehlmann, Philipp Erben, Tilman Bostel

Publikováno v: Blood. 110:28-28

Most patients with chronic myelogenous leukemia (CML) relapse after discontinuation of imatinib (IM, Glivec®/Gleevec™). Thus, current recommendations suggest a lifelong IM therapy even in complete molecular responders. However, in view of potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d72341a129f2e0e8c277db5b6bf1ac2
https://doi.org/10.1182/blood.v110.11.28.28

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání