Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Simone Mortal"'
Autor:
Renza Spelat, Nie Jihua, Cesar Adolfo Sánchez Triviño, Simone Pifferi, Diletta Pozzi, Matteo Manzati, Simone Mortal, Irene Schiavo, Federica Spada, Melania Eva Zanchetta, Tamara Ius, Ivana Manini, Irene Giulia Rolle, Pietro Parisse, Ana P. Millán, Ginestra Bianconi, Fabrizia Cesca, Michele Giugliano, Anna Menini, Daniela Cesselli, Miran Skrap, Vincent Torre
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-15 (2022)
Abstract Seizures represent a frequent symptom in gliomas and significantly impact patient morbidity and quality of life. Although the pathogenesis of tumor-related seizures is not fully understood, accumulating evidence indicates a key role of the p
Externí odkaz:
https://doaj.org/article/c0fb562c60244c99a29a1aba74600efd
Autor:
Nicola Galvanetto, Zhongjie Ye, Arin Marchesi, Simone Mortal, Sourav Maity, Alessandro Laio, Vincent Torre
Publikováno v:
eLife, Vol 11 (2022)
Single-molecule force spectroscopy (SMFS) uses the cantilever tip of an atomic force microscope (AFM) to apply a force able to unfold a single protein. The obtained force-distance curve encodes the unfolding pathway, and from its analysis it is possi
Externí odkaz:
https://doaj.org/article/9d826dc82a7a449982692ff29cd8e071
Autor:
Fabio Falleroni, Ulisse Bocchero, Simone Mortal, Yunzhen Li, Zhongjie Ye, Dan Cojoc, Vincent Torre
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103807- (2022)
Summary: There is growing evidence suggesting that mechanical properties of CNS neurons may play an important regulatory role in cellular processes. Here, we employ an oscillatory optical tweezers (OOT) to exert a local indentation with forces in the
Externí odkaz:
https://doaj.org/article/d2fa8367d0ab4c52a72043ced14dcafc
Autor:
Simone Mortal
Publikováno v:
STEMedicine, Vol 2, Iss 6 (2021)
Microtubules (MTs) are fundamental polymers composed by α and β tubulin, they provide integrity to neuronal cell and are necessaries in intracellular trafficking and organization. The extension and retraction of MTs occur with the addition or remov
Externí odkaz:
https://doaj.org/article/b189c6fdcacd43af98834e7325699bed
Autor:
Ulisse Bocchero, Fabio Falleroni, Simone Mortal, Yunzhen Li, Dan Cojoc, Trevor Lamb, Vincent Torre
Publikováno v:
PLoS Biology, Vol 18, Iss 7, p e3000750 (2020)
Photoreceptors are specialized cells devoted to the transduction of the incoming visual signals. Rods are able also to shed from their tip old disks and to synthesize at the base of the outer segment (OS) new disks. By combining electrophysiology, op
Externí odkaz:
https://doaj.org/article/0e0e416fdaee4adfaa9c22900eadd1d6
Autor:
Simone Mortal, Federico Iseppon, Andrea Perissinotto, Elisa D'Este, Dan Cojoc, Luisa M. R. Napolitano, Vincent Torre
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
During neurite development, Actin Waves (AWs) emerge at the neurite base and move up to its tip, causing a transient retraction of the Growth Cone (GC). Many studies have shown that AWs are linked to outbursts of neurite growth and, therefore, contri
Externí odkaz:
https://doaj.org/article/5463f6a1c64c4a72ad3996a5fdafb402
Autor:
Zhongjie Ye, Nicola Galvanetto, Arin Marchesi, Simone Mortal, Sourav Maity, Alessandro Laio, Vincent Torre
Publikováno v:
eLife, 11:e77427. ELIFE SCIENCES PUBLICATIONS LTD
Single-molecule force spectroscopy (SMFS) uses the cantilever tip of an atomic force microscope (AFM) to apply a force able to unfold a single protein. The obtained force-distance curve encodes the unfolding pathway, and from its analysis it is possi
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America 117 (2020): 21701–21710. doi:10.1073/pnas.2004909117
info:cnr-pdr/source/autori:Li, Yunzhen; Falleroni, Fabio; Mortal, Simone; Bocchero, Ulisse; Cojoc, Dan; Torre, Vincent/titolo:Calcium flares and compartmentalization in rod photoreceptors/doi:10.1073%2Fpnas.2004909117/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2020/pagina_da:21701/pagina_a:21710/intervallo_pagine:21701–21710/volume:117
Proceedings of the National Academy of Sciences of the United States of America 117 (2020): 21701–21710. doi:10.1073/pnas.2004909117
info:cnr-pdr/source/autori:Li, Yunzhen; Falleroni, Fabio; Mortal, Simone; Bocchero, Ulisse; Cojoc, Dan; Torre, Vincent/titolo:Calcium flares and compartmentalization in rod photoreceptors/doi:10.1073%2Fpnas.2004909117/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2020/pagina_da:21701/pagina_a:21710/intervallo_pagine:21701–21710/volume:117
Rod photoreceptors are composed of a soma and an inner segment (IS) connected to an outer segment (OS) by a thin cilium. OSs are composed of a stack of similar to 800 lipid discs surrounded by the plasma membrane where phototransduction takes place.
Autor:
Trevor D. Lamb, Dan Cojoc, Vincent Torre, Fabio Falleroni, Yunzhen Li, Simone Mortal, Ulisse Bocchero
Publikováno v:
PLoS Biology
PLoS biology 18 (2020). doi:10.1371/journal.pbio.3000750
info:cnr-pdr/source/autori:Bocchero, Ulisse; Falleroni, Fabio; Mortal, Simone; Li, Yunzhen; Cojoc, Dan; Lamb, Trevor; Torre, Vincent/titolo:Mechanosensitivity is an essential component of phototransduction in vertebrate rods/doi:10.1371%2Fjournal.pbio.3000750/rivista:PLoS biology/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:18
PLoS Biology, Vol 18, Iss 7, p e3000750 (2020)
PLoS biology 18 (2020). doi:10.1371/journal.pbio.3000750
info:cnr-pdr/source/autori:Bocchero, Ulisse; Falleroni, Fabio; Mortal, Simone; Li, Yunzhen; Cojoc, Dan; Lamb, Trevor; Torre, Vincent/titolo:Mechanosensitivity is an essential component of phototransduction in vertebrate rods/doi:10.1371%2Fjournal.pbio.3000750/rivista:PLoS biology/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:18
PLoS Biology, Vol 18, Iss 7, p e3000750 (2020)
Photoreceptors are specialized cells devoted to the transduction of the incoming visual signals. Rods are able also to shed from their tip old disks and to synthesize at the base of the outer segment (OS) new disks. By combining electrophysiology, op