Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Simone Michelan-Duarte"'
Autor:
Ivani Pauli, Celso de O. Rezende Jr., Brian W. Slafer, Marco A. Dessoy, Mariana L. de Souza, Leonardo L. G. Ferreira, Abraham L. M. Adjanohun, Rafaela S. Ferreira, Luma G. Magalhães, Renata Krogh, Simone Michelan-Duarte, Ricardo Vaz Del Pintor, Fernando B. R. da Silva, Fabio C. Cruz, Luiz C. Dias, Adriano D. Andricopulo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Cruzain, the main cysteine protease of Trypanosoma cruzi, plays key roles in all stages of the parasite’s life cycle, including nutrition acquisition, differentiation, evasion of the host immune system, and invasion of host cells. Thus, inhibition
Externí odkaz:
https://doaj.org/article/8b05c18bef4c4cee9ab7ee11d594e168
Autor:
Rafael Augusto Alves Ferreira, Celso de Oliveira Rezende Junior, Pablo David Grigol Martinez, Paul John Koovits, Bruna Miranda Soares, Leonardo L G Ferreira, Simone Michelan-Duarte, Rafael Consolin Chelucci, Adriano D Andricopulo, Mariana K Galuppo, Silvia R B Uliana, An Matheeussen, Guy Caljon, Louis Maes, Simon Campbell, Jadel M Kratz, Charles E Mowbray, Luiz Carlos Dias
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009196 (2021)
Leishmaniasis is a major infectious disease with hundreds of thousands of new cases and over 20,000 deaths each year. The current drugs to treat this life-threatening infection have several drawbacks such as toxicity and long treatment regimens. A li
Externí odkaz:
https://doaj.org/article/219308c5bea148d9a0c7045ba017f44b
Autor:
Simone Michelan-Duarte, Julia M. Souza, Camila H. Ogihara, Lucas dos S. Mello, José Wilmo da Cruz Júnior, Adriano D. Andricopulo, María J. Dávila-Rodríguez, Leonardo L. G. Ferreira, Edward R. Dockal, David L. Palomino-Salcedo, Aldo Sena de Oliveira, Thiago Henrique Döring
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background: Schiff bases are synthetically accessible compounds that have been used in medicinal chemistry. Methods & results: In this work, 27 Schiff bases derived from diaminomaleonitrile were synthesized in high yields (80–98%). Molecular dockin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870eab8950b1b42a4c5c5e2fa97bbb0b
https://doi.org/10.4155/fmc-2021-0194
https://doi.org/10.4155/fmc-2021-0194
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1703:79-81
Snake venom PLA(2)s have been extensively studied due to their role in mediating and disrupting physiological processes such as coagulation, platelet aggregation and myotoxicity. The Ca(2+) ion bound to the putative calcium-binding loop is essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2166e015ae238516761e1ee98467136
https://doi.org/10.1016/j.bbapap.2004.08.008
https://doi.org/10.1016/j.bbapap.2004.08.008