Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Simone Lepper"'
Autor:
Ross G Douglas, Prajwal Nandekar, Julia-Elisabeth Aktories, Hirdesh Kumar, Rebekka Weber, Julia M Sattler, Mirko Singer, Simone Lepper, S Kashif Sadiq, Rebecca C Wade, Friedrich Frischknecht
Publikováno v:
PLoS Biology, Vol 16, Iss 7, p e2005345 (2018)
Cell motility is essential for protozoan and metazoan organisms and typically relies on the dynamic turnover of actin filaments. In metazoans, monomeric actin polymerises into usually long and stable filaments, while some protozoans form only short a
Externí odkaz:
https://doaj.org/article/c6c8f9fb8e4f4b53adfba2f20276c044
Autor:
Kartik S Bane, Simone Lepper, Jessica Kehrer, Julia M Sattler, Mirko Singer, Miriam Reinig, Dennis Klug, Kirsten Heiss, Jake Baum, Ann-Kristin Mueller, Friedrich Frischknecht
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005710 (2016)
Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter host cells. Here we show that the actin filament-binding protein coronin regulates gliding motility in Plasmodium berghei sporozoites, the highly motile forms o
Externí odkaz:
https://doaj.org/article/4dedf6d7420c4c4fafc10a887f9ad6ff
Autor:
Juha Vahokoski, Saligram Prabhakar Bhargav, Ambroise Desfosses, Maria Andreadaki, Esa-Pekka Kumpula, Silvia Muñico Martinez, Alexander Ignatev, Simone Lepper, Friedrich Frischknecht, Inga Sidén-Kiamos, Carsten Sachse, Inari Kursula
Publikováno v:
PLoS Pathogens, Vol 10, Iss 4, p e1004091 (2014)
Actins are highly conserved proteins and key players in central processes in all eukaryotic cells. The two actins of the malaria parasite are among the most divergent eukaryotic actins and also differ from each other more than isoforms in any other s
Externí odkaz:
https://doaj.org/article/c5325fd5c9e44a88a184c7df2fc0ead6
Autor:
Simone Lepper, Kirsten Heiss, Kartik Bane, Julia M. Sattler, Miriam Reinig, Friedrich Frischknecht, Ann-Kristin Mueller, Mirko Singer, Jake Baum, Dennis Klug, Jessica Kehrer
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005710 (2016)
PLoS Pathogens
PLoS Pathogens
Parasites causing malaria need to migrate in order to penetrate tissue barriers and enter host cells. Here we show that the actin filament-binding protein coronin regulates gliding motility in Plasmodium berghei sporozoites, the highly motile forms o
Autor:
Rebecca C. Wade, Julia-Elisabeth Aktories, Julia M. Sattler, Ross G. Douglas, Mirko Singer, Hirdesh Kumar, S. Kashif Sadiq, Friedrich Frischknecht, Rebekka Weber, Prajwal P. Nandekar, Simone Lepper
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 7, p e2005345 (2018)
PLoS Biology, Vol 16, Iss 7, p e2005345 (2018)
Cell motility is essential for protozoan and metazoan organisms and typically relies on the dynamic turnover of actin filaments. In metazoans, monomeric actin polymerises into usually long and stable filaments, while some protozoans form only short a
Publikováno v:
Journal of Microscopy. 238:21-26
Summary Recent technical developments allowed the accurate correlation of fluorescently labelled organelles in living cells to cryo-electron micrographs. We aimed at expanding this approach to Plasmodium berghei sporozoites, the motile forms of a rod
Autor:
Simone Lepper, Sylvia Münter
Publikováno v:
Cellular Microbiology. 11:855-862
Publikováno v:
Biotechnology Journal. 3:995-998
Infectious diseases have played a substantial part in shaping the history of humanity. In a discussion at a recent EMBL-EMBO science and society symposium entitled ‘The future of our species’, several experts discussed how infectious diseases are
Publikováno v:
Imaging & Microscopy. 9:50-53
Cryo-electron tomography was used for studying the molecular organization of the cytoplasm in intact cells. Flat areas of cells grown on EM grids and preserved by rapid freezing within milliseconds were imaged in 3D. In the resulting maps the selecte
Publikováno v:
Journal of Biological Chemistry. 281:24781-24789
The NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli is composed of 13 subunits called NuoA through NuoN and contains one FMN and 9 iron-sulfur clusters as redox groups. Electron transfer from NADH to ubiquinone is coupled with the tr