Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Simone Ladel"'
Autor:
Nora Langreder, Dorina Schäckermann, Doris Meier, Marlies Becker, Maren Schubert, Stefan Dübel, Thomas Reinard, Stefanie Figge-Wegener, Kristine Roßbach, Wolfgang Bäumer, Simone Ladel, Michael Hust
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Insect bite hypersensitivity (IBH) is the most common allergic skin disease of horses. It is caused by insect bites of the Culicoides spp. which mediate a type I/IVb allergy with strong involvement of eosinophil cells. No specific treatment
Externí odkaz:
https://doaj.org/article/6ff4edd772434189b50b3655420751c3
Autor:
Lena Marie Spindler, Andreas Feuerhake, Simone Ladel, Cemre Günday, Johannes Flamm, Nazende Günday-Türeli, Emre Türeli, Günter E. M. Tovar, Katharina Schindowski, Carmen Gruber-Traub
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Intranasal delivery has gained prominence since 1990, when the olfactory mucosa was recognized as the window to the brain and the central nervous system (CNS); this has enabled the direct site specific targeting of neurological diseases for the first
Externí odkaz:
https://doaj.org/article/0bc5b38c9c4c4324aa92d8aa4239dc66
Autor:
Frank Maigler, Simone Ladel, Johannes Flamm, Stella Gänger, Barbara Kurpiers, Stefanie Kiderlen, Ronja Völk, Carmen Hamp, Sunniva Hartung, Sebastian Spiegel, Arghavan Soleimanizadeh, Katharina Eberle, Rebecca Hermann, Lukas Krainer, Claudia Pitzer, Katharina Schindowski
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1904 (2021)
Intranasal drug delivery is a promising approach for the delivery of drugs to the CNS, but too heterogenous, unprecise delivery methods without standardization decrease the quality of many studies in rodents. Thus, the lack of a precise and region-sp
Externí odkaz:
https://doaj.org/article/9cc3636f978846548c41bf6687931047
Autor:
Simone Ladel, Patrick Schlossbauer, Johannes Flamm, Harald Luksch, Boris Mizaikoff, Katharina Schindowski
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 367 (2019)
Background: The epithelial layer of the nasal mucosa is the first barrier for drug permeation during intranasal drug delivery. With increasing interest for intranasal pathways, adequate in vitro models are required. Here, porcine olfactory (OEPC) and
Externí odkaz:
https://doaj.org/article/04f060906b704f49a70b7559a3b64cc8
Autor:
Simone Ladel, Johannes Flamm, Arghavan Soleimani Zadeh, Dorothea Filzwieser, Julia-Christina Walter, Patrick Schlossbauer, Ralf Kinscherf, Katharina Lischka, Harald Luksch, Katharina Schindowski
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 107 (2018)
Background: The use of therapeutic antibodies for the treatment of neurological diseases is of increasing interest. Nose-to-brain drug delivery is one strategy to bypass the blood brain barrier. The neonatal Fc receptor (FcRn) plays an important role
Externí odkaz:
https://doaj.org/article/bcc0181516f346f088d49f47f6be1f9a
Autor:
Claudia Pitzer, Sebastian Spiegel, Johannes Flamm, Frank Maigler, Sunniva Hartung, Ronja Völk, Carmen Hamp, Katharina Schindowski, Katharina Eberle, Arghavan Soleimanizadeh, Stefanie Kiderlen, Barbara Kurpiers, Lukas Krainer, Simone Ladel, Stella Gänger, Rebecca Hermann
Publikováno v:
Pharmaceutics, Vol 13, Iss 1904, p 1904 (2021)
Pharmaceutics
Volume 13
Issue 11
Pharmaceutics
Volume 13
Issue 11
Intranasal drug delivery is a promising approach for the delivery of drugs to the CNS, but too heterogenous, unprecise delivery methods without standardization decrease the quality of many studies in rodents. Thus, the lack of a precise and region-sp
Publikováno v:
Journal of Comparative Neurology. 526:412-424
The midbrain is an important subcortical area involved in distinct functions such as multimodal integration, movement initiation, bottom-up, and top-down attention. Our group is particularly interested in cellular computation of multisensory integrat
Autor:
Boris Mizaikoff, Harald Luksch, Katharina Schindowski, Johannes Flamm, Patrick Schlossbauer, Simone Ladel
Publikováno v:
Pharmaceutics
Pharmaceutics; Volume 11; Issue 8; Pages: 367
Pharmaceutics, Vol 11, Iss 8, p 367 (2019)
Pharmaceutics; Volume 11; Issue 8; Pages: 367
Pharmaceutics, Vol 11, Iss 8, p 367 (2019)
Background: The epithelial layer of the nasal mucosa is the first barrier for drug permeation during intranasal drug delivery. With increasing interest for intranasal pathways, adequate in vitro models are required. Here, porcine olfactory (OEPC) and
Autor:
Johannes Flamm, Boris Mizaikoff, Rebecca Hermann, Patrick Schlossbauer, Simone Ladel, Alina Handl, Helena Herzog, Thomas Hummel, Frank Maigler, Katharina Schindowski
Publikováno v:
Pharmaceutics
Volume 12
Issue 11
Volume 12
Issue 11
Although we have recently reported the involvement of neonatal Fc receptor (FcRn) in intranasal transport, the transport mechanisms are far from being elucidated. Ex vivo porcine olfactory tissue, primary cells from porcine olfactory epithelium (OEPC