Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Simone Kurt"'
Autor:
Kerstin Blum, Pauline Schepsky, Philip Derleder, Philipp Schätzle, Fahmi Nasri, Philipp Fischer, Jutta Engel, Simone Kurt
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Noise-induced cochlear synaptopathy is characterized by irreversible loss of synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) despite normal hearing thresholds. We analyzed hearing performance and cochlear structure in C57B
Externí odkaz:
https://doaj.org/article/d56b50c7176e46b29ec9f9e219a19f7b
Autor:
Martin Mamach, Mariella Kessler, Jens P Bankstahl, Florian Wilke, Lilli Geworski, Frank M Bengel, Simone Kurt, Georg Berding
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205044 (2018)
Activation studies with positron emission tomography (PET) in auditory implant users explained some of the mechanisms underlying the variability of achieved speech comprehension. Since future developments of auditory implants will include studies in
Externí odkaz:
https://doaj.org/article/0b991bd0510f4948a451c6d35ebcdf1b
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33130 (2012)
Heterozygous mutations of the human FOXP2 transcription factor gene cause the best-described examples of monogenic speech and language disorders. Acquisition of proficient spoken language involves auditory-guided vocal learning, a specialized form of
Externí odkaz:
https://doaj.org/article/9fa419d68ab6459fb65840b84dedc51e
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23483 (2011)
Ap-2 transcription factors comprise a family of 5 closely related sequence-specific DNA binding proteins that play pivotal and non-redundant roles in embryonic organogenesis. To investigate the function of Ap-2δ, wδe analyzed its expression during
Externí odkaz:
https://doaj.org/article/27fcdf15c2cf4c5db9262971dab71d3f
Autor:
Simone Kurt, Anke Deutscher, John M Crook, Frank W Ohl, Eike Budinger, Christoph K Moeller, Henning Scheich, Holger Schulze
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1735 (2008)
Brains decompose the world into discrete objects of perception, thereby facing the problem of how to segregate and selectively address similar objects that are concurrently present in a scene. Theoretical models propose that this could be achieved by
Externí odkaz:
https://doaj.org/article/ead89d66d2f14afe844be630b13af9fa
Publikováno v:
Biological Chemistry. 404:607-617
The α2δ3 auxiliary subunit of voltage-activated calcium channels is required for normal synaptic transmission and precise temporal processing of sounds in the auditory brainstem. In mice its loss additionally leads to an inability to distinguish am
Publikováno v:
eNeuro. 9(2)
Temporal processing of complex sounds is a fundamental and complex task in hearing and a prerequisite for processing and understanding vocalization, speech, and prosody. Here, we studied response properties of neurons in the inferior colliculus (IC)
Publikováno v:
Brain Stimulation, Vol 11, Iss 5, Pp 1161-1174 (2018)
Background Auditory midbrain implant users cannot achieve open speech perception and have limited frequency resolution. It remains unclear whether the spread of excitation contributes to this issue and how much it can be compensated by current-focusi
Autor:
Christoph K. Moeller, Marlies Knipper, Ulrike Zimmermann, Winfried Neuhuber, Lukas Rüttiger, Matthias Sausbier, Harald van Straaten, Niels Brandt, Holger Schulze, Simone Kurt, Jennifer Kindler, Jutta Engel, Ulrike Sausbier, Peter Ruth
Publikováno v:
The FASEB Journal
Large conductance, voltage- and Ca2+-activated K+ (BK) channels in inner hair cells (IHCs) of the cochlea are essential for hearing. However, germline deletion of BKα, the pore-forming subunit KCNMA1 of the BK channel, surprisingly did not affect he
Publikováno v:
Neuroscience Letters. 463:219-222
The effect of oral application of Ginkgo biloba extract EGb 761® on auditory discrimination learning in Mongolian gerbils was investigated using discrimination tasks with three different degrees of difficulty and two protocols for administration sta