Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Simone Korten"'
Autor:
Dagmar Hildebrand, Konrad A. Bode, David Rieß, Daniela Cerny, Anna Waldhuber, Franziska Römmler, Julia Strack, Simone Korten, Joachim H.C. Orth, Thomas Miethke, Klaus Heeg, Katharina F. Kubatzky
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 910-917 (2014)
Bacterial components are recognized by the immune system through activation of the inflammasome, eventually causing processing of the proinflammatory cytokine interleukin-1β (IL-1β), a pleiotropic cytokine and one of the most important mediators of
Externí odkaz:
https://doaj.org/article/34638665148e4950ada9e6c7f331d29c
Publikováno v:
Parasitology
SUMMARYTh2-biased inflammation with eosinophilia and IgE production is a hallmark of helminth infections. It is pronounced in hyperreactive onchocerciasis patients (‘sowda’ or ‘local form’), who efficiently kill microfilariae resulting in sev
Publikováno v:
Microbes and Infection. 12:555-564
Transforming growth factor-beta (TGF-beta) is a key cytokine in immune regulation, cell differentiation, development, wound healing, and tissue remodelling. It mediates immunosuppression in filarial infections facilitating parasite persistence, while
Publikováno v:
Parasitology Research
Ectopic secondary lymph follicles emerge in patients with autoimmune or infectious diseases, e.g. in the synovium in rheumatoid arthritis or the skin in Borrelia burgdorferi infection, but ectopic localisations in the skin are rarely described for he
Autor:
Masaru Taniguchi, Simone Korten, Richard J. Anderson, Robert E. Sinden, Adrian V. S. Hill, Stephan D. Gadola, Eric G. Sheu, Carolyn M. Hannan
Publikováno v:
Infection and Immunity. 73:849-858
Understanding the protective mechanism in the liver induced by recombinant vaccines against the pre-erythrocytic stages of malaria is important for vaccine development. Most studies in mice have focused on splenic and peripheral blood T cells and ide
Autor:
Stephen M. Laidlaw, Geoffrey Butcher, Eric G. Sheu, Adrian V. S. Hill, Sarah C. Gilbert, Richard J. Anderson, Michael A. Skinner, Robert E. Sinden, Simone Korten, Carolyn M. Hannan
Publikováno v:
Scopus-Elsevier
Sterile immunity can be provided against the pre-erythrocytic stages of malaria by IFN-γ-secreting CD8+ T cells that recognize parasite-infected hepatocytes. In this study, we have investigated the use of attenuated fowlpox virus (FPV) strains as re
Publikováno v:
Acta Tropica. 70:217-231
In onchocerciasis, variations of the host's immune responsiveness produce a spectrum of clinical manifestations ranging from the common generalized to the rare hyperreactive form (sowda). For further characterization of the immune response, the local
Publikováno v:
Parasitology. 116:257-268
Onchocercomata with a defined worm population were analysed to elucidate the distribution of mast cells. Nodules with live females were classified according to the presence or absence of microfilariae. Immunohistochemical staining was performed using
Autor:
Marc Kirchner, Norbert W. Brattig, Hanno Steen, Fred A. Hamprecht, Franziska Zickmann, Dominic Winter, Amit Tzur, Buote Xu, Simone Korten, Bernhard Y. Renard
Publikováno v:
Molecular & Cellular Proteomics : MCP
Currently, the reliable identification of peptides and proteins is only feasible when thoroughly annotated sequence databases are available. Although sequencing capacities continue to grow, many organisms remain without reliable, fully annotated refe
Autor:
Jens Urny, Benjamin Otto, Benjamin J. Marsland, Simone Korten, Wiebke Hartmann, Bernhard Fleischer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(4)
Granzyme (gzm) A and B, proteases of NK cells and T killer cells, mediate cell death, but also cleave extracellular matrices, inactivate intracellular pathogens, and induce cytokines. Moreover, macrophages, Th2 cells, regulatory T cells, mast cells,