Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Simone Helmig"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Herbal preparations of willow bark (Salix cortex) are available in many countries as non-prescription medicines for pain and inflammation, and also as dietary supplements. Currently only little information on toxicity and drug interaction potential o
Externí odkaz:
https://doaj.org/article/2e80a48977a74ff1ae3c72947cbdbd3d
Publikováno v:
Journal of Occupational Medicine and Toxicology, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Summary Former uranium miners of the Wismut Company, East Germany, have been exposed to ionizing radiation from radon decay products and therefore were at high risk for lung cancer. Since histological types of cancer in the so called Wismut
Externí odkaz:
https://doaj.org/article/3c09b2f5bfac4849b2c4205571413b15
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 134:643-651
A standardized in vitro system of human lung cells (A459) in RPMI medium is beneficial for investigations concerning the toxicity of inhalable biopersistent fibrous or granular dusts such as asbestos or titanium dioxide. However, the use of non-biope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0831790b39f98a6e471eb1392f856e70
https://doi.org/10.1007/s10973-018-7480-8
https://doi.org/10.1007/s10973-018-7480-8
Publikováno v:
Molecular Medicine Reports. 16:9233-9241
The conversion rates of different metabolic pathways summarized as a metabolic signature mirror the physiological functions and the general physiological status of a cell. The present study compared the impact of crocidolite and chrysotile asbestos,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13aa40b9b43e279739caba71470991a1
https://doi.org/10.3892/mmr.2017.7729
https://doi.org/10.3892/mmr.2017.7729
Publikováno v:
Molecular medicine reports. 17(6)
The hazards of granular and fibrous particles have been associated with the generation of reactive oxygen species (ROS), which in turn is often associated with physicochemical properties exhibited by these particles. In the present study, the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66448f6f94c256a3919f4ffd8b2438b1
https://pubmed.ncbi.nlm.nih.gov/29693699
https://pubmed.ncbi.nlm.nih.gov/29693699
Autor:
Ursula Kirmse, Frank H. Wilhelm, Katja Winzeler, Christian Cajochen, Mary Princip, Klaus Bader, Evelin Hug, Annette Voellmin, Simone Helmig
Background and objectives: After a previous report demonstrated blunted heart rate (HR) reactivity in association with adverse childhood experiences (ACEs) [Voellmin, A., Winzeler, K., Hug, E., Wilhelm, F. H., Schaefer, V., Gaab, J., … Bader, K. (2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37853fe9c97638cefce3e0aa04c881cc
Autor:
Simone Helmig, Reginald Matejec, Markus A. Weigand, Hagen Maxeiner, Friederike Dülfer, Joachim Schneider, Andreas Böning, Sibylle Wenzel, Nina Krehbiehl, Solaiman Mufti, Klaus-Dieter Schlüter
Publikováno v:
Journal of Cellular Physiology. 229:1681-1689
Cardiosphere-derived cells (CDCs) were cultured from human, murine, and rat hearts. Diluted supernatant (conditioned-medium) of the cultures improved the contractile behavior of isolated rat cardiomyocytes (CMCs). This effect is mediated by the parac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b3a042b44a715cc002cd9cb4a95dd8
https://doi.org/10.1002/jcp.24613
https://doi.org/10.1002/jcp.24613
Publikováno v:
Mutagenesis. 29:237-240
Benzo(a)pyrene (BaP), a primary component of tobacco smoke, is activated by cytochrome P450 1B1 (CYP1B1). Smokers homozygous for the C-allele (*1/*1) at the CYP1B1 Leu432Val polymorphism have shown increased CYP1B1 expression, compared to smokers hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6311450086eb1730a33d0a3af5d34a32
https://doi.org/10.1093/mutage/geu010
https://doi.org/10.1093/mutage/geu010
Publikováno v:
Molecular Medicine Reports. 9:217-228
Natural and synthetic fibres and particles are being introduced into the workplace and environment daily. Comparative analyses of the induced signalling pathways are essential in order to understand the potential hazards of these particles. To identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e8ccd2cf326d57757861959f5444a
https://doi.org/10.3892/mmr.2013.1765
https://doi.org/10.3892/mmr.2013.1765
Autor:
Monika Schreiner, Evelyn Lamy, Franziska Kupke, Sascha Rohn, Grace A. Odongo, Corinna Herz, Stefanie Platz, María Matilde Bartolomé Rodríguez, Franziska S. Hanschen, Simone Helmig
Publikováno v:
Scientific Reports
Isothiocyanates are the most intensively studied breakdown products of glucosinolates from Brassica plants and well recognized for their pleiotropic effects against cancer but also for their genotoxic potential. However, knowledge about the bioactivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b938b249ccbcdb25ee3bf39ee60eb0f
http://europepmc.org/articles/PMC5121622
http://europepmc.org/articles/PMC5121622