Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Simone Hebele"'
Autor:
Norbert Meidenbauer, Peter Hohenberger, Timo Gaiser, Karen J. Fritchie, Arndt Hartmann, Bernd Kasper, Till Braunschweig, Sanja Schmeck, Jens Jakob, Stefan Wiemann, Philip Ströbel, Matthias Bieg, Caterina Giannini, Eva Wardelmann, Simone Hebele, Naveed Ishaque, Udo Kontny, Horia Sirbu, Abbas Agaimy, Robert Grützmann, Roland Eils, Evgeny A. Moskalev, Matthias Schwarzbach, Florian Haller, Rainer Will
Publikováno v:
The American Journal of Pathology. 191:602-617
Solitary fibrous tumors (SFTs) harbor recurrent NAB2-STAT6 gene fusions, promoting constitutional up-regulation of oncogenic early growth response 1 (EGR1)-dependent gene expression. SFTs with the most common canonical NAB2 exon 4-STAT6 exon 2 fusion
Autor:
Bruno Märkl, Arndt Hartmann, Ramona Erber, Matthias Bieg, Stefan Wiemann, Stephan Ihrler, Florian Haller, Heinrich Iro, Alena Skálová, Christa Winkelmann, Simone Hebele, Susanne Blank, S Müller, Abbas Agaimy, Roland Eils, Martina Baněčková, Evgeny A. Moskalev, Johannes Zenk
Publikováno v:
American Journal of Surgical Pathology. 43:1264-1272
Recently, we discovered the recurrent genomic rearrangement [t(4;9)(q13;q31)] enabling upregulation of the transcription factor Nuclear Receptor Subfamily 4 Group A Member 3 (NR4A3) through enhancer hijacking as the oncogenic driver event in acinic c
Autor:
Jana Fassunke, Sabine Merkelbach-Bruse, Nicole Pfarr, Roland Penzel, Volker Endris, Simone Hebele, Evgeny A. Moskalev, Florian Haller
Publikováno v:
International Journal of Molecular Medicine
In the growing field of personalised medicine, the analysis of numerous potential targets is becoming a challenge in terms of work load, tissue availability, as well as costs. The molecular analysis of non-small cell lung cancer (NSCLC) has shifted f
Autor:
Abbas Agaimy, Arndt Hartmann, Ralf J. Rieker, Evgeny A. Moskalev, Matthias W. Beckmann, Simone Hebele, Grit Mehlhorn, Florian Haller, Alexander Hein
Publikováno v:
Pathology. 45:388-392
Summary Aims The pathogenesis and classification of multicentric smooth muscle tumours with benign appearance and concurrent/metachronous uterine and peritoneal involvement is controversial and may on occasion be diagnostically challenging. Leiomyoma
Autor:
Evgeny A. Moskalev, Arndt Hartmann, Florian Haller, Helmut König, Sergey E. Mastitsky, Florian S. Fuchs, Horia Sirbu, Simone Hebele, Abbas Agaimy, Ralf J. Rieker, Robert Stöhr, Carsten Boltze
Publikováno v:
Virchows Archiv
Detection of activating EGFR mutations in NSCLC is the prerequisite for individualised therapy with receptor tyrosine kinase inhibitors (TKI). In contrast, mutant downstream effector KRAS is associated with TKI resistance. Accordingly, EGFR mutation