Colicins and Salmocins – New Classes of Plant-Made Non-antibiotic Food Antibacterials

Autor: Simone Hahn-Löbmann, Anett Stephan, Steve Schulz, Tobias Schneider, Anton Shaverskyi, Daniel Tusé, Anatoli Giritch, Yuri Gleba

Publikováno v: Frontiers in Plant Science, Vol 10 (2019)

Recently, several plant-made recombinant proteins received favorable regulatory review as food antibacterials in the United States through the Generally Recognized As Safe (GRAS) regulatory procedure, and applications for others are pending. These fo

Externí odkaz: https://doaj.org/article/0ff5b39c71fc449e9c1c401a5c452e75

Broad and Efficient Control of Klebsiella Pathogens by Peptidoglycan-Degrading and Pore-Forming Bacteriocins Klebicins

Autor: Erna Denkovskienė, Astra Vitkauskienė, Benita Stočkūnaitė, Steve Schulz, Aušra Ražanskienė, Urtė Starkevič, Audrius Misiūnas, Anatoli Giritch, Yuri Gleba, Šarūnas Paškevičius, Simone Hahn-Löbmann

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific reports, London : Nature Publishing Group, 2019, vol. 9, no. 1, 15422, p. 1-11
Scientific Reports

Gram-negative bacteria belonging to the genus Klebsiella are important nosocomial pathogens, readily acquiring resistance to all known antibiotics. Bacteriocins, non-antibiotic antibacterial proteins, have been earlier proposed as potential therapeut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27dc0a325cf6858aeea3a6a501325f59
http://link.springer.com/article/10.1038/s41598-019-51969-1

Colicins and Salmocins – New Classes of Plant-Made Non-antibiotic Food Antibacterials

Autor: Tobias Schneider, Anton Shaverskyi, Anett Stephan, Simone Hahn-Löbmann, Anatoli Giritch, Yuri Gleba, Daniel Tuse, Steve Schulz

Publikováno v: Frontiers in Plant Science
Frontiers in Plant Science, Vol 10 (2019)

Recently, several plant-made recombinant proteins received favorable regulatory review as food antibacterials in the United States through the Generally Recognized As Safe (GRAS) regulatory procedure, and applications for others are pending. These fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba444fbdb1b759972b918ae16baac2b4
http://europepmc.org/articles/PMC6465592

Simple Purification of Nicotiana benthamiana-Produced Recombinant Colicins: High-Yield Recovery of Purified Proteins with Minimum Alkaloid Content Supports the Suitability of the Host for Manufacturing Food Additives

Autor: Anett Stephan, Anatoli Giritch, Yuri Gleba, Fred Rosche, Simone Hahn-Löbmann, Mirko Buchholz

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 1; Pages: 95
International Journal of Molecular Sciences, Vol 19, Iss 1, p 95 (2017)

Colicins are natural non-antibiotic bacterial proteins with a narrow spectrum but an extremely high antibacterial activity. These proteins are promising food additives for the control of major pathogenic Shiga toxin-producing E. coli serovars in meat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421beee7db6db5403e5f89416cbcdc13
https://pubmed.ncbi.nlm.nih.gov/29286298

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

Autor: Anja Nickstadt, Thomas Lahaye, Heidi Scholze, Simone Hahn, Angelika Landgraf, Sabine Kay, Jens Boch, Sebastian Schornack, Ulla Bonas

Publikováno v: Science. 326:1509-1512

TAL Order Xanthomonas bacteria attack their plant hosts by delivering their own transcription-activator–like (TAL) proteins into the plant cell nucleus and alter the plant's gene regulation (see the Perspective by Voytas and Joung ). Moscou and Bog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b073da2bdc786b305da9dc77f249869c
https://doi.org/10.1126/science.1178811