Výsledky vyhledávání - "Simone G. van Breda"

Akademický článek

Effects of Different Combinations of Phytochemical-Rich Fruits and Vegetables on Chronic Disease Risk Markers and Gene Expression Changes: Insights from the MiBLEND Study, a Randomized Trial

Autor: Julia N. DeBenedictis, Courtney Murrell, Duncan Hauser, Marcel van Herwijnen, Bart Elen, Theo M. de Kok, Simone G. van Breda

Publikováno v: Antioxidants, Vol 13, Iss 8, p 915 (2024)

Adequate fruit and vegetable (F and V) intake, as recommended by the World Health Organization (over 400 g/day), is linked to reduced chronic disease risk. However, human intervention trials, especially with whole F and V and in complex combinations,

Externí odkaz: https://doaj.org/article/7fbb792b3ab9451b885b082418e8056e

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Akademický článek

Correction: Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256

Autor: Nicolaj S. Bischoff, Héloïse Proquin, Marlon J. Jetten, Yannick Schrooders, Marloes C. M. Jonkhout, Jacco J. Briedé, Simone G. van Breda, Danyel G. J. Jennen, Estefany I. Medina-Reyes, Norma L. Delgado-Buenrostro, Yolanda I. Chirino, Henk van Loveren, Theo M. de Kok

Publikováno v: Nanomaterials, Vol 13, Iss 21, p 2888 (2023)

In the published publication [...]

Externí odkaz: https://doaj.org/article/c8548edcf51f4851b932093df2b10c62

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Akademický článek

Impact of Processing Method and Storage Time on Phytochemical Concentrations in an Antioxidant-Rich Food Mixture

Autor: Julia N. DeBenedictis, Theo M. de Kok, Simone G. van Breda

Publikováno v: Antioxidants, Vol 12, Iss 6, p 1252 (2023)

Foods high in phytochemicals are known for their role in the prevention of chronic disease development, but after processing and storage, such food products may lose part of their functionality as these compounds are sensitive to the impact of proces

Externí odkaz: https://doaj.org/article/f907ebdfe723461da134163fca57acb9

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Akademický článek

Reply to Kaminski, N.E.; Cohen, S.M. Comment on 'Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256'

Publikováno v: Nanomaterials, Vol 13, Iss 9, p 1552 (2023)

We appreciate the interest in our article describing transcriptome changes in a transgenic mouse model carrying an APC gene mutation and would like to reply to the reader [...]

Externí odkaz: https://doaj.org/article/b88bc0b67aea469da3f6bec087dad66d

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Akademický článek

Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers

Autor: Simone G. van Breda, Karen Mathijs, Virág Sági-Kiss, Gunter G. Kuhnle, Ben van der Veer, Rena R. Jones, Rashmi Sinha, Mary H. Ward, Theo M. de Kok

Publikováno v: Environmental Health, Vol 18, Iss 1, Pp 1-12 (2019)

Abstract Background Nitrate is converted to nitrite in the human body and subsequently can react with amines and amides in the gastrointestinal tract to form N-nitroso compounds (NOCs), which are known to be carcinogenic in animals. Humans can be exp

Externí odkaz: https://doaj.org/article/121c777d0d814fdda21b7a250fe8d2e9

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Akademický článek

The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer

Publikováno v: Nanomaterials, Vol 12, Iss 8, p 1256 (2022)

Titanium dioxide (TiO2) is present in many different food products as the food additive E171, which is currently scrutinized due to its potential adverse effects, including the stimulation of tumor formation in the gastrointestinal tract. We develope

Externí odkaz: https://doaj.org/article/8e4a4d9481344b9a9b9922d9f6f42772

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Akademický článek

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

Autor: Alice Limonciel, Simone G. van Breda, Xiaoqi Jiang, Gregory D. Tredwell, Anja Wilmes, Lydia Aschauer, Alexandros P. Siskos, Agapios Sachinidis, Hector C. Keun, Annette Kopp-Schneider, Theo M. de Kok, Jos C. S. Kleinjans, Paul Jennings

Publikováno v: Frontiers in Genetics, Vol 9 (2018)

The discovery of the epigenetic regulation of transcription has provided a new source of mechanistic understanding to long lasting effects of chemicals. However, this information is still seldom exploited in a toxicological context and studies of che

Externí odkaz: https://doaj.org/article/3d4ec61caa4f42d49159c0721f28c25c

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A Lyophilized Red Grape Pomace Containing Proanthocyanidin-Rich Dietary Fiber Induces Genetic and Metabolic Alterations in Colon Mucosa of Female C57BL/6J Mice

Autor: Daneida, Lizarraga, M Pilar, Vinardell, Véronique, Noé, Joost H, van Delft, Gema, Alcarraz-Vizán, Simone G, van Breda, Yvonne, Staal, Ulrich L, Günther, John B, Carrigan, Michelle A, Reed, Carlos J, Ciudad, Josep L, Torres, Marta, Cascante

Publikováno v: Journal of Nutrition
Journal of Nutrition, 141(9), 1597-1604. Oxford University Press

Diet plays a decisive role in promoting or preventing colon cancer. However, the specific effects of some nutrients remain unclear. The capacity of fruit and vegetables to prevent cancer has been associated with their fiber and antioxidant compositio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a39fa2a505d5d860144aed6f1897d0

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