Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Simone Florian"'
Autor:
Mike F Müller, Simone Florian, Stefanie Pommer, Martin Osterhoff, R Steven Esworthy, Fong-Fong Chu, Regina Brigelius-Flohé, Anna P Kipp
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72055 (2013)
The selenoprotein glutathione peroxidase-2 (GPx2) appears to have a dual role in carcinogenesis. While it protected mice from colon cancer in a model of inflammation-triggered carcinogenesis (azoxymethane and dextran sodium sulfate treatment), it pro
Externí odkaz:
https://doaj.org/article/4196b780d9e84b638f831001aafcab3f
Publikováno v:
Archives of toxicology, 96(3):933–944
Juices of Brassica vegetables are mutagenic and form characteristic DNA adducts in bacteria and mammalian cells. In this study, we examined whether such adducts are also formed in vivo in animal models. Rats fed raw broccoli ad libitum in addition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c059e1627c5dde5f953462bb0733165
https://link.springer.com/article/10.1007/s00204-021-03216-8#Sec18
https://link.springer.com/article/10.1007/s00204-021-03216-8#Sec18
Autor:
Fabian Schumacher, Simone Florian, Inga Mewis, Melanie Wiesner-Reinhold, Hansruedi Glatt, Monika Schreiner, Gitte Barknowitz
Publikováno v:
Archives of Toxicology. 93:1515-1527
We previously showed that purified 1-methoxy-3-indolylmethyl (1-MIM) glucosinolate, a secondary plant metabolite in Brassica species, is mutagenic in various in vitro systems and forms DNA and protein adducts in mouse models. In the present study, we
Autor:
Melanie, Wiesner-Reinhold, Gitte, Barknowitz, Simone, Florian, Inga, Mewis, Fabian, Schumacher, Monika, Schreiner, Hansruedi, Glatt
Publikováno v:
Archives of toxicology. 93(6)
We previously showed that purified 1-methoxy-3-indolylmethyl (1-MIM) glucosinolate, a secondary plant metabolite in Brassica species, is mutagenic in various in vitro systems and forms DNA and protein adducts in mouse models. In the present study, we
Publikováno v:
Lecture Notes in Civil Engineering ISBN: 9783030036751
In line with the growing demand of digital documentation in the field of Cultural Heritage, nowadays survey technologies allow an immediate reading of a whole system directly in a 3D environment. The Photogrammetry Laboratory at the Iuav University o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2218a87a9348206fa5e2b0ce219076a
https://doi.org/10.1007/978-3-030-03676-8_19
https://doi.org/10.1007/978-3-030-03676-8_19
Autor:
Annette M. Krais, Eszter Nagy, Volker M. Arlt, David H. Phillips, Walter Meinl, Iveta Mrizova, Simone Florian, Amin Mirza, František Bárta, Maggie Liu, Hansruedi Glatt, Marlies Thomann, Heinz H. Schmeiser, Klaus Kopka, Meirion Richards, Marie Stiborová
Publikováno v:
Arlt, V M, Meinl, W, Florian, S, Nagy, E, Barta, F, Thomann, M, Mrizova, I, Krais, A M, Liu, M, Richards, M, Mirza, A, Kopka, K, Phillips, D H, Glatt, H, Stiborova, M & Schmeiser, H H 2017, ' Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone ', Archives of Toxicology, vol. 91, no. 4, pp. 1957-1975 . https://doi.org/10.1007/s00204-016-1808-6
Archives of Toxicology
Archives of Toxicology
Exposure to aristolochic acid (AA) causes aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN). Conflicting results have been found for the role of human sulfotransferase 1A1 (SULT1A1) contributing to the metabolic activation of a
Autor:
Stephan Schmidt, Mareike Bernau, Simone Florian, Wolfram Engst, Bernhard H. Monien, Hansruedi Glatt, Markus Kramer, Gitte Barknowitz
Publikováno v:
Chemical Research in Toxicology. 27:188-199
1-Methoxy-3-indolylmethyl (1-MIM) glucosinolate (GLS) occurring in cabbage, broccoli, and other cruciferous plants is a potent mutagen requiring metabolic activation by myrosinase present in plant cells and intestinal bacteria. We previously reported
Autor:
Heinz Himmelbauer, Hansruedi Glatt, Kristin Herrmann, Dieter Schrenk, Klaus E. Appel, Tobias Nolden, Alexander Cartus, Simone Florian, Walter Meinl, Wolfram Engst
Publikováno v:
Carcinogenesis. 35:935-941
Methyleugenol--a natural constituent of herbs and spices--is hepatocarcinogenic in rodent models. It can form DNA adducts after side-chain hydroxylation and sulfation. We previously demonstrated that human sulfotransferases (SULTs) 1A1 and 1A2 as wel
Autor:
Simone Florian, Bernhard H. Monien, Albrecht Seidel, Heinz Frank, Fabian Schumacher, Lisa Steinhauser, Anke Schnapper, Klaus Albert, Hansruedi Glatt, Wolfram Engst
Publikováno v:
Analytical Chemistry. 84:6256-6262
1-Methoxy-3-indolylmethyl (1-MIM) glucosinolate, present at substantial levels in several food crops (e.g., broccoli and cabbage), forms DNA adducts in vitro and is mutagenic to bacterial and mammalian cells after activation by the plant enzyme myros
Autor:
Morana Bauer-Marinovic, Gisela Dobbernack, Hansruedi Glatt, Bernhard H. Monien, Walter Meinl, Simone Florian, Felicitas Taugner
Publikováno v:
Molecular Nutrition & Food Research. 56:593-600
Scope It was reported that the Maillard product 5-hydroxymethylfurfural (HMF) initiates and promotes aberrant crypt foci (ACF) in rat colon. We studied whether 5-sulfooxymethylfurfural (SMF), an electrophilic and mutagenic metabolite of HMF, is able