Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Simone Durry"'
Autor:
Katharina Everaerts, Pawan Thapaliya, Nils Pape, Simone Durry, Sara Eitelmann, Eleni Roussa, Ghanim Ullah, Christine R. Rose
Publikováno v:
Cells, Vol 12, Iss 23, p 2675 (2023)
Ischemic conditions cause an increase in the sodium concentration of astrocytes, driving the breakdown of ionic homeostasis and exacerbating cellular damage. Astrocytes express high levels of the electrogenic sodium-bicarbonate cotransporter1 (NBCe1)
Externí odkaz:
https://doaj.org/article/b08869e758e243e296f1ac4d9b6d80b9
Autor:
Sara Eitelmann, Jonathan Stephan, Katharina Everaerts, Simone Durry, Nils Pape, Niklas J. Gerkau, Christine R. Rose
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4836
Malfunction of astrocytic K+ regulation contributes to the breakdown of extracellular K+ homeostasis during ischemia and spreading depolarization events. Studying astroglial K+ changes is, however, hampered by a lack of suitable techniques. Here, we
Publikováno v:
J Neurophysiol
Spontaneous neuronal and astrocytic activity in the neonate forebrain is believed to drive the maturation of individual cells and their integration into complex brain-region-specific networks. The previously reported forms include bursts of electrica
Publikováno v:
Cerebral cortex 28(12), 4264-4280 (2017). doi:10.1093/cercor/bhx280
In core regions of ischemic stroke, disruption of blood flow causes breakdown of ionic gradients and, ultimately, calcium overload and cell death. In the surrounding penumbra, cells may recover upon reperfusion, but recovery is hampered by additional
Autor:
Christine R. Rose, Simone Durry, Liang Peng, Dan Song, Junnan Xu, Leif Hertz, Niklas J. Gerkau
Publikováno v:
Journal of Neuroscience Research. 93:1019-1030
Neuronal excitation increases extracellular K(+) concentration ([K(+)]o) in vivo and in incubated brain tissue by stimulation of postsynaptic glutamatergic receptors and by channel-mediated K(+) release during action potentials. Convincing evidence e
Autor:
Simone Durry, Martin C. Stock, Ulrich Rüther, Karl W. Kafitz, Christine R. Rose, Alexandra E. Schreiner, Kohichi Tanaka, Tomomi Aida
Publikováno v:
Journal of Comparative Neurology. 522:204-224
Astrocytes express two sodium-coupled transporters, glutamate-aspartate transporter (GLAST) and glutamate transporter-1 (GLT-1), which are essential for the maintenance of low extracellular glutamate levels. We performed a comparative analysis of the
Autor:
Christian Steinhäuser, Karl W. Kafitz, Christine R. Rose, Daniel Koch, Simone Durry, Peter Hochstrate, Nicole Haack, Gerald Seifert, Jonathan Stephan
Publikováno v:
Glia; Vol 60
Glia
Glia
Increased ammonium (NH(4) (+) ) concentration in the brain is the prime candidate responsible for hepatic encephalopathy (HE), a serious neurological disorder caused by liver failure and characterized by disturbed glutamatergic neurotransmission and
Publikováno v:
Journal of Visualized Experiments : JoVE
Electrical activity in the brain is accompanied by significant ion fluxes across membranes, resulting in complex changes in the extracellular concentration of all major ions. As these ion shifts bear significant functional consequences, their quantit
Publikováno v:
Journal of Neurophysiology. 94:441-453
Mg2+-extrusion from Mg2+-loaded neurons of the leech, Hirudo medicinalis, is mediated mainly by Na+/Mg2+antiport. However, in a number of leech neurons, Mg2+is extruded in the nominal absence of extracellular Na+, indicating the existence of an addit
Autor:
Leif, Hertz, Niklas J, Gerkau, Junnan, Xu, Simone, Durry, Dan, Song, Christine R, Rose, Liang, Peng
Publikováno v:
Journal of neuroscience research. 93(7)
Neuronal excitation increases extracellular K(+) concentration ([K(+)]o) in vivo and in incubated brain tissue by stimulation of postsynaptic glutamatergic receptors and by channel-mediated K(+) release during action potentials. Convincing evidence e