Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Simone Diermeier"'
Autor:
Anja Kathrin Wege, Dominik Chittka, Stefan Buchholz, Monika Klinkhammer-Schalke, Simone Diermeier-Daucher, Florian Zeman, Olaf Ortmann, Gero Brockhoff
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background The sensitivity of estrogen receptor-positive breast cancers to tamoxifen treatment varies considerably, and the molecular mechanisms affecting the response rates are manifold. The human epidermal growth factor receptor-related re
Externí odkaz:
https://doaj.org/article/0b0307b1ee124192bee8988bedc1b8d3
Autor:
Georg Breier, Simone Diermeier-Daucher, Guido Bold, Hannes C.A. Drexler, Sven A. Lang, Andreas Gaumann, Oliver Stoeltzing, Jeanette Marjorie Wood, Elisabeth Buchdunger
Publikováno v:
International Journal of Oncology
Leiomyosarcomas remain challenging tumors to manage and novel therapy strategies besides radiation and conventional chemotherapy are needed. Targeting angiogenesis by inhibition of vascular endothelial growth factor (VEGF) receptor tyrosine kinases (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004c57709a19699fb546795620c27900
https://doi.org/10.3892/ijo.2014.2683
https://doi.org/10.3892/ijo.2014.2683
Publikováno v:
mAbs. 4:614-622
The trifunctional antibody ertumaxomab bivalently targets the human epidermal growth factor receptor 2 (Her2) on epithelial (tumor) cells and the T cell specific CD3 antigen, and its Fc region is selectively recognized by Fcγ type I/III receptor-pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89d9b8d98e25637717464964b899dbf
https://doi.org/10.4161/mabs.21003
https://doi.org/10.4161/mabs.21003
Autor:
Ferdinand Hofstaedter, E. Schmidt-Bruecken, Simone Diermeier, A. Vollmann, Gero Brockhoff, M. Plander, B. Heckel
Publikováno v:
Cell Proliferation. 40:488-507
Objectives: The potential of epidermal growth factor receptor (EGFR)‐ and Her2‐targeted antibodies Cetuximab, Pertuzumab and Trastuzumab, used in combination to inhibit cell proliferation of breast cancer cells in vitro, has not been extensively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef15d9a17df99b1692367dce3bbdd39f
https://doi.org/10.1111/j.1365-2184.2007.00449.x
https://doi.org/10.1111/j.1365-2184.2007.00449.x
Autor:
Ferdinand Hofstaedter, Stephan Schwarz, Gero Brockhoff, Christian Lottner, Arndt Hartmann, Ruth Knuechel, Simone Diermeier
Publikováno v:
The Journal of Pathology. 205:577-584
The determination of HER2/neu status in breast carcinomas has become essential for the selection of breast cancer patients for Herceptin therapy. Herceptin treatment is used in patients with metastatic breast carcinoma with HER2/neu protein overexpre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef359413ebde8c7b0deb1fc797a7a62c
https://doi.org/10.1002/path.1742
https://doi.org/10.1002/path.1742
Autor:
Anna, Machleidt, Stefan, Buchholz, Simone, Diermeier-Daucher, Florian, Zeman, Olaf, Ortmann, Gero, Brockhoff
Publikováno v:
BMC Cancer
Background Not only four but rather seven different human epidermal growth factor receptor related (Her) receptor tyrosine kinases (RTKs) have been described to be expressed in a variety of normal and neoplastic tissues: Her1, Her2, Her3, and additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4934d708f0eb03e017e41e76075afde5
https://pubmed.ncbi.nlm.nih.gov/24063248
https://pubmed.ncbi.nlm.nih.gov/24063248
Autor:
Jürgen Schlegel, Simone Diermeier-Daucher, Anca-Ligia Grosu, Justus Duyster, Raymonde Busch, Gero Brockhoff, Sabina Berezowska
Publikováno v:
International Journal of Molecular Medicine. 26
Targeted molecular therapies against the epidermal growth factor receptor (EGFR) are novel, promising and potentially radiosensitising therapeutic approaches in the treatment of glioblastoma, a highly malignant and treatment-refractory brain tumour.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3438f7049f37b9147403bd3520b34d33
https://doi.org/10.3892/ijmm_00000518
https://doi.org/10.3892/ijmm_00000518
Publikováno v:
Current Protocols in Cell Biology
Dynamic proliferation assessment via flow cytometry is legitimately supposed to be the most powerful tool for recording cell cycle kinetics in-vitro. The preeminent feature is a single cell-based multi-informative analysis by temporal high-resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157352db4442b168f6cdf471c581f506
https://pubmed.ncbi.nlm.nih.gov/20853345
https://pubmed.ncbi.nlm.nih.gov/20853345
Autor:
Simone Diermeier-Daucher, Frans A. Nauwelaers, Ferdinand Hofstaedter, Gero Brockhoff, Anja K. Wege, Elisabeth Schmidt-Brücken, Olaf Ortmann, Arabel Vollmann-Zwerenz, Andrea Sassen
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 77(4)
The prognostic significance of HER2 expression in human breast carcinomas is beyond dispute nowadays. The HER family of receptor tyrosine kinases comprises four members (HER1/ErbB1/EGFR, HER2/ErbB2, HER3/ErbB3, and HER4/ErbB4) that act in concert via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252af5f1f3f0310cdcb40687d54d9cd0
https://pubmed.ncbi.nlm.nih.gov/20151455
https://pubmed.ncbi.nlm.nih.gov/20151455
Autor:
Simone Diermeier-Daucher, Scott T. Clarke, Arabel Vollmann-Zwerenz, Gero Brockhoff, Dani Hill, Jolene Bradford
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 75(6)
Using the nucleoside analogue EdU (5-ethynyl-2'-deoxyuridine) for thymidine substitution instead of BrdU (5-bromo-2'-deoxyuridine) in cell proliferation assays has recently been proposed. However, the effect of EdU on cell viability, DNA synthesis, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34215d5071128410576c01221ace502a
https://pubmed.ncbi.nlm.nih.gov/19235202
https://pubmed.ncbi.nlm.nih.gov/19235202