Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Simone Cenci"'
Autor:
Maria Materozzi, Massimo Resnati, Cecilia Facchi, Matteo Trudu, Ugo Orfanelli, Tommaso Perini, Luigi Gennari, Enrico Milan, Simone Cenci
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Bone destruction, a major source of morbidity, is mediated by heightened differentiation and activity of osteoclasts (OC), highly specialized multinucleated myeloid cells endowed with unique bone-resorptive capacity. The molecular mechanisms
Externí odkaz:
https://doaj.org/article/eda159c0c6a1424dbc57da5d36ac6af1
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Climate actions by the private sector are crucial to cutting global emissions and meeting the climate targets set by the Paris Agreement. However, despite an increasing number of climate pledges, the emissions pathways of most companies are
Externí odkaz:
https://doaj.org/article/0cf4ff63ad37475281db361aa1559eac
Autor:
Massimo Resnati, Sara Pennacchio, Lisa Viviani, Tommaso Perini, Maria Materozzi, Ugo Orfanelli, Jessica Bordini, Raffaella Molteni, Mario Nuvolone, Matteo Da Vià, Francesca Lazzaroni, Niccolò Bolli, Simone Cenci, Enrico Milan
Publikováno v:
Haematologica, Vol 109, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/ba33c960f9454c9b90685c17760b950e
Autor:
Simone Cenci, Stephen Kealhofer
Publikováno v:
Journal of Finance and Data Science, Vol 8, Iss , Pp 214-232 (2022)
Capital structure theories are often formulated as causal narratives to explain which factors drive financing choices. These narratives are usually examined by estimating cross–sectional relations between leverage and its determinants. However, the
Externí odkaz:
https://doaj.org/article/57b954d394ef48638cdaa284cff72cea
Autor:
Andrea G. Locatelli, Simone Cenci
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Autophagy is a fundamental multi-tasking adaptive cellular degradation and recycling strategy. Following its causal implication in age-related decline, autophagy is currently among the most broadly studied and challenged mechanisms within aging resea
Externí odkaz:
https://doaj.org/article/f4203ed8c43d4fd7874aaa5737a2fa8d
Autor:
Matteo Trudu, Laura Oliva, Ugo Orfanelli, Alessandra Romano, Francesco Di Raimondo, Francesca Sanvito, Maurilio Ponzoni, Simone Cenci
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multiple myeloma grows by establishing multiple interactions with bone marrow cells. These include expansion of myeloid-derived suppressor cells, which drive immunoevasion via mechanisms that include arginase-1-driven depletion of L-arginine, thus in
Externí odkaz:
https://doaj.org/article/ee9ee6a946354a0890f7b365ec56d587
Autor:
Simone Bianciardi, Daniela Merlotti, Maria Materozzi, Christian Mingiano, Simone Cenci, Luigi Gennari
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100502- (2020)
Externí odkaz:
https://doaj.org/article/497080114db344f0bb9fd87d2cf7b30f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/da2e138abcf44a3685e5c601ba48fd03
Autor:
Chiara Fucci, Massimo Resnati, Elena Riva, Tommaso Perini, Elena Ruggieri, Ugo Orfanelli, Francesca Paradiso, Floriana Cremasco, Andrea Raimondi, Elena Pasqualetto, Mario Nuvolone, Luca Rampoldi, Simone Cenci, Enrico Milan
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108162- (2020)
Summary: FAM46C is a non-canonical poly(A) polymerase uniquely mutated in up to 20% of multiple myeloma (MM) patients, implying a tissue-specific tumor suppressor function. Here, we report that FAM46C selectively stabilizes mRNAs encoding endoplasmic
Externí odkaz:
https://doaj.org/article/ae1219dbb80b45f2be9d32a13af4f52b
Autor:
R Alessia Battista, Massimo Resnati, Cecilia Facchi, Elena Ruggieri, Floriana Cremasco, Francesca Paradiso, Ugo Orfanelli, Leone Giordano, Mario Bussi, Simone Cenci, Enrico Milan
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201621 (2018)
To cope with intrinsic and environmental stress, cancer cells rely on adaptive pathways more than non-transformed counterparts. Such non-oncogene addiction offers new therapeutic targets and strategies to overcome chemoresistance. In an attempt to st
Externí odkaz:
https://doaj.org/article/21aa9d9085bd4497aad2960c6f045097