Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Simone Camelliti"'
Autor:
Federica Cossu, Simone Camelliti, Daniele Lecis, Luca Sorrentino, Maria Teresa Majorini, Mario Milani, Eloise Mastrangelo
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6366-6374 (2021)
Inhibitors of apoptosis proteins (IAPs) are validated onco-targets, as their overexpression correlates with cancer onset, progression, diffusion and chemoresistance. IAPs regulate cell death survival pathways, inflammation, and immunity. Targeting IA
Externí odkaz:
https://doaj.org/article/c86117b4d2eb46419e5f2244e91de453
Autor:
Simone Camelliti, Valentino Le Noci, Francesca Bianchi, Claudia Moscheni, Francesca Arnaboldi, Nicoletta Gagliano, Andrea Balsari, Marina Chiara Garassino, Elda Tagliabue, Lucia Sfondrini, Michele Sommariva
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-20 (2020)
Abstract Immune checkpoint inhibitors (ICIs) have made a breakthrough in the treatment of different types of tumors, leading to improvement in survival, even in patients with advanced cancers. Despite the good clinical results, a certain percentage o
Externí odkaz:
https://doaj.org/article/4d7400b9bbc24ac089902f2f0ec236ff
Autor:
Francesca Bianchi, Michele Sommariva, Valentino Le Noci, Simone Camelliti, Nicoletta Gagliano, Marta Giussani, Andrea Balsari, Elda Tagliabue, Lucia Sfondrini
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248789 (2021)
Background1,25-dihydroxyvitamin D3 [1,25(OH)2D3] plays a role in calcium homeostasis but can also exert immunomodulatory effects. In lungs, characterized by a particular immunosuppressive environment primarily due to the presence of alveolar macropha
Externí odkaz:
https://doaj.org/article/9d3d66e41f7348ed92de79a9cf7b4719
Autor:
Maria Teresa Majorini, Mario Milani, Eloise Mastrangelo, Federica Cossu, Simone Camelliti, Luca Sorrentino, Daniele Lecis
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6366-6374 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6366-6374 (2021)
Graphical abstract
Highlights • Virtual docking vs type I BIRs of IAPs identified FC2 as a modulator of NF-kB. • FC2 is active as a single agent with no toxicity in normal cells. • The cytotoxic activity of FC2 is enhanced by TNF and by th
Highlights • Virtual docking vs type I BIRs of IAPs identified FC2 as a modulator of NF-kB. • FC2 is active as a single agent with no toxicity in normal cells. • The cytotoxic activity of FC2 is enhanced by TNF and by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6b25bf13118244ef9827f45d20e43b
https://doi.org/10.1016/j.csbj.2021.11.034
https://doi.org/10.1016/j.csbj.2021.11.034
Autor:
Michele Sommariva, Valentino Le Noci, Marina Chiara Garassino, Simone Camelliti, Lucia Sfondrini, Elda Tagliabue, Francesca Bianchi, Francesca Arnaboldi, Nicoletta Gagliano, Andrea Balsari, Claudia Moscheni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-20 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Immune checkpoint inhibitors (ICIs) have made a breakthrough in the treatment of different types of tumors, leading to improvement in survival, even in patients with advanced cancers. Despite the good clinical results, a certain percentage of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1352f4174c8d9e5efbb6d322fe86472a
http://link.springer.com/article/10.1186/s13046-020-01721-9
http://link.springer.com/article/10.1186/s13046-020-01721-9
Autor:
Elda Tagliabue, Simone Camelliti, Michele Sommariva, Valentino Le Noci, Francesca Bianchi, Andrea Balsari, Lucia Sfondrini
Publikováno v:
Cellular and Molecular Life Sciences
Like other body districts, lungs present a complex bacteria community. An emerging function of lung microbiota is to promote and maintain a state of immune tolerance, to prevent uncontrolled and not desirable inflammatory response caused by inhalatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0950cccd1baabfa2a846ac084c36f8c7
http://europepmc.org/articles/PMC7326824
http://europepmc.org/articles/PMC7326824
Autor:
Chiara Storti, Simone Camelliti, Valentino Le Noci, Mario P. Colombo, Mariangela Figini, Alessandra Cataldo, Michele Sommariva, Francesca Bianchi, Lucia Sfondrini, Francesca Arnaboldi, Elena Jachetti, Serena Indino, Nicoletta Gagliano, Andrea Balsari, Elda Tagliabue
Publikováno v:
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4081, p 4081 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 4081, p 4081 (2021)
Simple Summary We evaluated the contribution of macrophages to the effect of combinatorial immunotherapeutic treatments based on TLR9 stimulation (with CpG-ODNs) and PD-1 blockade in an ovarian cancer preclinical model. We observed a strong reduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f223f876c44d435362ff9a8d1a29f464
Autor:
Nicoletta Gagliano, Andrea Balsari, Michele Sommariva, Elda Tagliabue, Valentino Le Noci, Simone Camelliti, Francesca Bianchi, Marta Giussani, Lucia Sfondrini
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248789 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248789 (2021)
Background 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] plays a role in calcium homeostasis but can also exert immunomodulatory effects. In lungs, characterized by a particular immunosuppressive environment primarily due to the presence of alveolar macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6bffc6cbb48c6427e91cb1b12311ee
http://europepmc.org/articles/PMC8007042
http://europepmc.org/articles/PMC8007042
Autor:
Tommaso Mello, Simone Camelliti, Lucia Sfondrini, Elisa Martini, Michele Sommariva, Cristiano Rumio, Marinos Kallikourdis, Fabrizio Marcucci, Claudia Sardi
Publikováno v:
Life sciences. 264
Aims Obesity represents a global health problem. Excessive caloric intake promotes the release of inflammatory mediators by hypertrophic adipocytes and obesity-induced inflammation is now recognized as a risk factor for the development of several dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e18762833793ec8fc91cb97b651ea3
https://pubmed.ncbi.nlm.nih.gov/33141040
https://pubmed.ncbi.nlm.nih.gov/33141040
Autor:
Olivier Deas, Patrizia Casalini, Ilaria Plantamura, Alessandra Cataldo, Jean-Gabriel Judde, Elda Tagliabue, Stefano Cairo, Elvira D'Ippolito, Marta Giussani, Marilena V. Iorio, Simone Camelliti, Claudia Piovan
Publikováno v:
Oncotarget
Trastuzumab is the standard treatment for HER2+ breast cancer (BC) patients, and even though it significantly improved their clinical outcome, 50% of them do not benefit from this drug and disease recurs, underlining the need of reliable predictive b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6b9f28ecee3d1a46b76f7244ca5721
https://doi.org/10.18632/oncotarget.24723
https://doi.org/10.18632/oncotarget.24723