Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Simone Brogi"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/0dcaea4931c34a2e89b4929edc542ef3
Autor:
Sara Rossi, Vanessa Tatangelo, Maria Dichiara, Stefania Butini, Sandra Gemma, Simone Brogi, Silvia Pasquini, Martina Cappello, Fabrizio Vincenzi, Katia Varani, Ludovica Lopresti, Margherita Malchiodi, Chiara Carrara, Alessandro Gozzetti, Monica Bocchia, Giuseppe Marotta, Laura Patrussi, Gabriele Carullo, Cosima T. Baldari, Giuseppe Campiani
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116537- (2024)
Chronic Lymphocytic Leukemia (CLL) patients have a defective expression of the proapoptotic protein p66Shc and of its transcriptional factor STAT4, which evoke molecular abnormalities, impairing apoptosis and worsening disease prognosis and severity.
Externí odkaz:
https://doaj.org/article/5b5fa73fa7a44b40b6f5ece58f9ee513
Autor:
Mehreen Zia, Shagufta Parveen, Nusrat Shafiq, Maryam Rashid, Ariba Farooq, Musaab Dauelbait, Muhammad Shahab, Ahmad Mohammad Salamatullah, Simone Brogi, Mohammed Bourhia
Publikováno v:
ACS Omega, Vol 9, Iss 2, Pp 2161-2182 (2024)
Externí odkaz:
https://doaj.org/article/80647fe50d2b4895ab1f9ccf8ee174e5
Publikováno v:
Foods, Vol 13, Iss 13, p 1960 (2024)
Intermittent fasting (IF) has been indicated as a valuable alternative to the classical caloric restriction dietary regimen for lowering body weight and preventing obesity-related complications, such as metabolic syndrome and type II diabetes. Howeve
Externí odkaz:
https://doaj.org/article/76caf19f1d2c4fefa51a0018802f8576
Autor:
Joe Anthony H. Manzano, Simone Brogi, Vincenzo Calderone, Allan Patrick G. Macabeo, Nicanor Austriaco
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 610 (2024)
Candidiasis is considered an emerging public health concern because of the occurrence of drug-resistant Candida strains and the lack of an available structurally diverse antifungal drug armamentarium. The indole alkaloid globospiramine from the antic
Externí odkaz:
https://doaj.org/article/f4ca182515af42e7be2432904a15e4e3
Autor:
Mohammad M. Al-Sanea, Abdelrahman Hamdi, Simone Brogi, Samar S. Tawfik, Dina I. A. Othman, Mahmoud Elshal, Hidayat Ur Rahman, Della G. T. Parambi, Rehab M. Elbargisy, Samy Selim, Ehab M. Mostafa, Ahmed A. B. Mohamed
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A novel series of 12 antipyrine derivatives containing 1,3,4-oxadiazoles (4a-d), 1,3,4-thiadiazoles (6a-d), and pyrimidines (8a-d), was preparedand assessed for its potential in vitro COX-2 inhibitors. Compared to Celecoxib, compounds 4b-d and 8d wer
Externí odkaz:
https://doaj.org/article/81d6be4508e84755a23af8c5f039439b
Autor:
Joe Anthony H. Manzano, Elian Angelo Abellanosa, Jose Paolo Aguilar, Simone Brogi, Chia-Hung Yen, Allan Patrick G. Macabeo, Nicanor Austriaco
Publikováno v:
Cells, Vol 13, Iss 9, p 772 (2024)
Bisindole alkaloids are a source of inspiration for the design and discovery of new-generation anticancer agents. In this study, we investigated the cytotoxic and antiproliferative activities of three spirobisindole alkaloids from the traditional ant
Externí odkaz:
https://doaj.org/article/8a462d3abaef4ce6aff6a057c2676e7e
Autor:
Shagufta Parveen, Aneeqa Batool, Nusrat Shafiq, Maryam Rashid, Ayesha Sultan, Gezahign Fentahun Wondmie, Yousef A. Bin Jardan, Simone Brogi, Mohammed Bourhia
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Alzheimer’s disease (AD) is more commonly found in women than in men as the risk increases with age. Phytochemicals are screened in silico from Punica granatum peels for their antioxidant activity to be utilized for Alzheimer’s disease. Alzheimer
Externí odkaz:
https://doaj.org/article/0bea9815e278465db38faf98e438baaf
Autor:
Nusrat Shafiq, Aiman Mehroze, Warda Sarwar, Uzma Arshad, Shagufta Parveen, Maryam Rashid, Ariba Farooq, Naila Rafiq, Gezahign Fentahun Wondmie, Yousef A. Bin Jardan, Simone Brogi, Mohammed Bourhia
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Severe acute respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is the etiological virus of Coronavirus Disease 2019 (COVID-19) which has been a public health concern due to its high morbidity and high mortality. Hence, the search for drugs that incapac
Externí odkaz:
https://doaj.org/article/94155ea9a8a8458398f85cb65c28f591
Publikováno v:
Computation, Vol 11, Iss 12, p 255 (2023)
In this study, we applied a computer-based protocol to identify novel antioxidant agents that can reduce oxidative stress (OxS), which is one of the main hallmarks of several disorders, including cancer, cardiovascular disease, and neurodegenerative
Externí odkaz:
https://doaj.org/article/b65d02c201b342f297277379ebdf70b5