Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Simone Braig"'
Autor:
Carolin M.-L. Gleissner, Carolin L. Pyka, Wolfgang Heydenreuter, Thomas F. Gronauer, Carina Atzberger, Vadim S. Korotkov, Weiting Cheng, Stephan M. Hacker, Angelika M. Vollmar, Simone Braig, Stephan A. Sieber
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
Externí odkaz:
https://doaj.org/article/8a702a398cd544bc9174ef6ea10e4433
Autor:
Fabian Koczian, Olga Nagło, Jan Vomacka, Binje Vick, Phil Servatius, Themistoklis Zisis, Britta Hettich, Uli Kazmaier, Stephan A. Sieber, Irmela Jeremias, Stefan Zahler, Simone Braig
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
Combination chemotherapy has proven to be a favorable strategy to treat acute leukemia. However, the introduction of novel compounds remains challenging and is hindered by a lack of understanding of their mechanistic interactions with established dru
Externí odkaz:
https://doaj.org/article/1c116d8e9a6c4e9e97dc21f8d511861f
Autor:
Simone Braig, B U Sebastian Schmidt, Katharina Stoiber, Chris Händel, Till Möhn, Oliver Werz, Rolf Müller, Stefan Zahler, Andreas Koeberle, Josef A Käs, Angelika M Vollmar
Publikováno v:
New Journal of Physics, Vol 17, Iss 8, p 083007 (2015)
The invasive potential of cancer cells strongly depends on cellular stiffness, a physical quantity that is not only regulated by the mechanical impact of the cytoskeleton but also influenced by the membrane rigidity. To analyze the specific role of m
Externí odkaz:
https://doaj.org/article/dda7d94c296e4bb6a9b830a92ffad63d
Autor:
Angelika M. Vollmar, Laurent Meijer, Stefan Zahler, Fabian Bischoff, Johanna Liebl, Christine A. Kressirer, Simone Braig
PDF file, 77K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3017d945b01c34ee124c5ee2c4b55fa7
https://doi.org/10.1158/0008-5472.22396224.v1
https://doi.org/10.1158/0008-5472.22396224.v1
Autor:
Angelika M. Vollmar, Laurent Meijer, Stefan Zahler, Fabian Bischoff, Johanna Liebl, Christine A. Kressirer, Simone Braig
PDF file, 59K, S1. Reduced attachment of 6BIO treated T24 cells as determined by xCELLigence experiments (left). DMSO treated cells served as control. S2. Representative images of scratch assays of T24 cells treated with 6BIO,vMe-6BIO, 5BIO and 7BIO.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e6b1b2619c1bda5f320368bcf44510
https://doi.org/10.1158/0008-5472.22396221.v1
https://doi.org/10.1158/0008-5472.22396221.v1
Autor:
Angelika M. Vollmar, Laurent Meijer, Stefan Zahler, Fabian Bischoff, Johanna Liebl, Christine A. Kressirer, Simone Braig
PDF file, 70K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38725ccc865066eaf43c36891a0cae2a
https://doi.org/10.1158/0008-5472.22396218
https://doi.org/10.1158/0008-5472.22396218
Autor:
Pengyu Wang, Thomas Klassmüller, Cornelia A. Karg, Maibritt Kretschmer, Stefan Zahler, Simone Braig, Franz Bracher, Angelika M. Vollmar, Simone Moser
Publikováno v:
Biological Chemistry. 403:421-431
Since the first report on a yeast three-hybrid system, several approaches have successfully utilized different setups for discovering targets of small molecule drugs. Compared to broadly applied MS based target identification approaches, the yeast th
Autor:
Thomas F. Gronauer, Vadim S. Korotkov, Simone Braig, Weiting Cheng, Stephan A. Sieber, Carolin L. Pyka, Angelika M. Vollmar, Carolin M.-L. Gleissner, Carina Atzberger, Wolfgang Heydenreuter, Stephan M. Hacker
Publikováno v:
ACS Central Science
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
ACS Central Science, 5 (7)
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
ACS Central Science, 5 (7)
The natural product neocarzilin A (NCA) was discovered decades ago, and despite its potent cytotoxic effects no mode of action studies have been performed up to date. Synthesis of neocarzilins A, B, and C and a stereoisomer of NCA provided insights i
Autor:
Lena Feuerer, David Stieglitz, Bernd Echtenacher, Claus Hellerbrand, Sigrid Karrer, Simone Braig, Anja-Katrin Bosserhoff, Peter Dietrich, Stephanie Arndt, Susanne Lamm, Silke Kuphal
Publikováno v:
Oncogene. 38:609-621
Melanoma is the deadliest form of skin cancer with rising incidence, creating a significant health problem. We discovered increased expression of bone morphogenetic protein 6 (BMP6) in melanoma cells and tissues, and observed that BMP6 deficiency cau
Autor:
Stefan Zahler, Jochen Feldmann, Katharina Stoiber, Melanie Ulrich, Carla Pernpeintner, Theobald Lohmüller, Oliver Werz, Andreas Koeberle, Rolf Müller, Olga Nagło, Simone Braig, Siwei Zhang
Publikováno v:
British Journal of Cancer
Background: Although altered membrane physiology has been discussed within the context of cancer, targeting membrane characteristics by drugs being an attractive therapeutic strategy has received little attention so far. Methods: Various acetyl-CoA c