Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Simone Borgoni"'
Autor:
Lukas Beumers, Efstathios-Iason Vlachavas, Simone Borgoni, Luisa Schwarzmüller, Luca Penso-Dolfin, Birgitta E. Michels, Emre Sofyali, Sara Burmester, Daniela Heiss, Heike Wilhelm, Yosef Yarden, Dominic Helm, Rainer Will, Angela Goncalves, Stefan Wiemann
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Intratumoral heterogeneity impacts the success or failure of anti-cancer therapies. Here, we investigated the evolution and mechanistic heterogeneity in clonal populations of cell models for estrogen receptor positive breast cancer. To this
Externí odkaz:
https://doaj.org/article/d79daab67d374819bdec862b9405046a
Autor:
Josefine Radke, Naveed Ishaque, Randi Koll, Zuguang Gu, Elisa Schumann, Lina Sieverling, Sebastian Uhrig, Daniel Hübschmann, Umut H. Toprak, Cristina López, Xavier Pastor Hostench, Simone Borgoni, Dilafruz Juraeva, Fabienne Pritsch, Nagarajan Paramasivam, Gnana Prakash Balasubramanian, Matthias Schlesner, Shashwat Sahay, Marc Weniger, Debora Pehl, Helena Radbruch, Anja Osterloh, Agnieszka Korfel, Martin Misch, Julia Onken, Katharina Faust, Peter Vajkoczy, Dag Moskopp, Yawen Wang, Andreas Jödicke, Lorenz Trümper, Ioannis Anagnostopoulos, Dido Lenze, Ralf Küppers, Michael Hummel, Clemens A. Schmitt, Otmar D. Wiestler, Stephan Wolf, Andreas Unterberg, Roland Eils, Christel Herold-Mende, Benedikt Brors, ICGC MMML-Seq Consortium, Reiner Siebert, Stefan Wiemann, Frank L. Heppner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Primary lymphomas of the central nervous system (PCNSL) are defined as diffuse large B-cell lymphomas (DLBCL) confined to the CNS. Here, the authors complete whole genome sequencing and RNA-seq to characterize 51 PCNSLs, and find common mutations in
Externí odkaz:
https://doaj.org/article/cd868cc84a9442afabebbc3638875fab
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 4, Pp n/a-n/a (2022)
Abstract Coronavirus disease 2019 (COVID‐19) has transformed very quickly into a world pandemic with severe and unexpected consequences on human health. Concerted efforts to generate better diagnostic and prognostic tools have been ongoing. Researc
Externí odkaz:
https://doaj.org/article/15d4d427613f425e86f061c88f737296
Autor:
Maryam Soleimani Dodaran, Simone Borgoni, Emre Sofyalı, Pernette J. Verschure, Stefan Wiemann, Perry D. Moerland, Antoine H. C. van Kampen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Estrogen receptor (ER) positive breast cancer is often effectively treated with drugs that inhibit ER signaling, i.e., tamoxifen (TAM) and aromatase inhibitors (AIs). However, 30% of ER+ breast cancer patients develop resistance t
Externí odkaz:
https://doaj.org/article/05e1012ebaf343358c57d489aa9794d1
Autor:
Moitza Principe, Simone Borgoni, Mariafrancesca Cascione, Michelle Samuel Chattaragada, Sammy Ferri-Borgogno, Michela Capello, Sara Bulfamante, Jennifer Chapelle, Francesca Di Modugno, Paola Defilippi, Paola Nisticò, Paola Cappello, Chiara Riganti, Stefano Leporatti, Francesco Novelli
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Background We have previously shown that in pancreatic ductal adenocarcinoma (PDA) cells, the glycolytic enzyme alpha-enolase (ENO1) also acts as a plasminogen receptor and promotes invasion and metastasis formation. Moreover, ENO1 silencing
Externí odkaz:
https://doaj.org/article/fdfdff63e09d4d67b093c8b4ac4b6767
Autor:
Simone Borgoni, Andrea Iannello, Santina Cutrupi, Paola Allavena, Maurizio D'Incalci, Francesco Novelli, Paola Cappello
Publikováno v:
OncoImmunology, Vol 7, Iss 2 (2018)
Pancreatic Ductal Adenocarcinoma (PDA) is characterized by a complex tumor microenvironment that supports its progression, aggressiveness and resistance to therapies. The delicate interplay between cancer and immune cells creates the conditions for P
Externí odkaz:
https://doaj.org/article/04914c4231fb423caf5c8245cfb935b0
Autor:
Stefan Wiemann, Lukas Beumers, Efstathios Vlachavas, Simone Borgoni, Luisa Schwarzmüller, Luca Penso-Dolfin, Birgitta Michels, Emre Sofyali, Sara Burmester, Daniela Heiss, Heike Wilhelm, Yosef Yarden, Dominic Helm, Rainer Will, Angela Goncalves
Intratumoral heterogeneity drastically impacts the success or failure of anti-cancer therapies. Here, we investigated the evolution and mechanistic heterogeneity in clonal populations of cell models for estrogen receptor positive breast cancer. To th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d927924eadff8374421e8058e623363c
https://doi.org/10.21203/rs.3.rs-2813593/v1
https://doi.org/10.21203/rs.3.rs-2813593/v1
Autor:
Yosef Yarden, Eytan Ruppin, Gad Getz, Aviv Regev, Joan S. Brugge, Rami I. Aqeilan, Trever G. Bivona, Laxmi Parida, Stefan Wiemann, Jideofor Ezike, Collin M. Blakely, Moshe Oren, Andrea Ardizzoni, Michelangelo Fiorentino, Mattia Lauriola, Brian P. Danysh, Diana Drago-Garcia, Youngmin Chung, Suvendu Giri, Arunachalam Sekar, Wei Wu, D. Lucas Kerr, Alexander Brandis, Sanju Sinha, Welles Robinson, Simone Borgoni, Rishita Chatterjee, Aakanksha Verma, Arturo Simoni-Nieves, Soma Ghosh, Rainer Will, Saptaparna Mukherjee, Moshit Lindzen, Sara Oster, Yaara Oren, Benny Zhitomirsky, Joo Sang Lee, Nishanth Belugali Nataraj, Ashish Noronha
Anticancer therapies have been limited by the emergence of mutations and other adaptations. In bacteria, antibiotics activate the SOS response, which mobilizes error-prone factors that allow for continuous replication at the cost of mutagenesis. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90156dccca93cef0832f1138ce45eef
https://doi.org/10.1158/2159-8290.c.6549711
https://doi.org/10.1158/2159-8290.c.6549711
Autor:
Yosef Yarden, Eytan Ruppin, Gad Getz, Aviv Regev, Joan S. Brugge, Rami I. Aqeilan, Trever G. Bivona, Laxmi Parida, Stefan Wiemann, Jideofor Ezike, Collin M. Blakely, Moshe Oren, Andrea Ardizzoni, Michelangelo Fiorentino, Mattia Lauriola, Brian P. Danysh, Diana Drago-Garcia, Youngmin Chung, Suvendu Giri, Arunachalam Sekar, Wei Wu, D. Lucas Kerr, Alexander Brandis, Sanju Sinha, Welles Robinson, Simone Borgoni, Rishita Chatterjee, Aakanksha Verma, Arturo Simoni-Nieves, Soma Ghosh, Rainer Will, Saptaparna Mukherjee, Moshit Lindzen, Sara Oster, Yaara Oren, Benny Zhitomirsky, Joo Sang Lee, Nishanth Belugali Nataraj, Ashish Noronha
Supplementary Figure from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b3d798497aa0ca157a505f562f91a6
https://doi.org/10.1158/2159-8290.22541643.v1
https://doi.org/10.1158/2159-8290.22541643.v1
Autor:
Yosef Yarden, Eytan Ruppin, Gad Getz, Aviv Regev, Joan S. Brugge, Rami I. Aqeilan, Trever G. Bivona, Laxmi Parida, Stefan Wiemann, Jideofor Ezike, Collin M. Blakely, Moshe Oren, Andrea Ardizzoni, Michelangelo Fiorentino, Mattia Lauriola, Brian P. Danysh, Diana Drago-Garcia, Youngmin Chung, Suvendu Giri, Arunachalam Sekar, Wei Wu, D. Lucas Kerr, Alexander Brandis, Sanju Sinha, Welles Robinson, Simone Borgoni, Rishita Chatterjee, Aakanksha Verma, Arturo Simoni-Nieves, Soma Ghosh, Rainer Will, Saptaparna Mukherjee, Moshit Lindzen, Sara Oster, Yaara Oren, Benny Zhitomirsky, Joo Sang Lee, Nishanth Belugali Nataraj, Ashish Noronha
Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e7bdbe0faeb9783a3dfad67e1dd091
https://doi.org/10.1158/2159-8290.22541646.v1
https://doi.org/10.1158/2159-8290.22541646.v1