Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Simone Bertolini"'
Autor:
Nadezda V. Volkova, Bettina Meier, Víctor González-Huici, Simone Bertolini, Santiago Gonzalez, Harald Vöhringer, Federico Abascal, Iñigo Martincorena, Peter J. Campbell, Anton Gartner, Moritz Gerstung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Recent research has shown that mutational signatures reflective of the history of a cancer can be detected in a cancer genome. Here, using whole genome sequencing of DNA repair deficient and proficient nematodes exposed to genotoxins, the authors sho
Externí odkaz:
https://doaj.org/article/586f62ed751f4d509ab638e75a89c6f7
Autor:
Bettina Meier, Nadezda V Volkova, Bin Wang, Víctor González-Huici, Simone Bertolini, Peter J Campbell, Moritz Gerstung, Anton Gartner
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258269 (2021)
Ionizing radiation (IR) is widely used in cancer therapy and accidental or environmental exposure is a major concern. However, little is known about the genome-wide effects IR exerts on germ cells and the relative contribution of DNA repair pathways
Externí odkaz:
https://doaj.org/article/ef6696afb0904d94b7bd7a54ee9601d7
Autor:
Bettina Meier, Nadezda V Volkova, Ye Hong, Simone Bertolini, Víctor González-Huici, Tsvetana Petrova, Simon Boulton, Peter J Campbell, Moritz Gerstung, Anton Gartner
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250291 (2021)
Maintaining genome integrity is particularly important in germ cells to ensure faithful transmission of genetic information across generations. Here we systematically describe germ cell mutagenesis in wild-type and 61 DNA repair mutants cultivated ov
Externí odkaz:
https://doaj.org/article/973c4a87eec54351a56521bb57b45e1a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 12, Pp 3875-3885 (2017)
Relatively little is known about the cross-talk between the spindle assembly checkpoint and the DNA damage response, especially in multicellular organisms. We performed a Caenorhabditis elegans forward genetic screen to uncover new genes involved in
Externí odkaz:
https://doaj.org/article/7490cc90552c4a96a2cce5a0ca3deff3
Autor:
Peter J. Campbell, Federico Abascal, Harald Vöhringer, Bettina Meier, Moritz Gerstung, Inigo Martincorena, Nadezda V. Volkova, Simone Bertolini, Víctor González-Huici, Anton Gartner, Santiago Gonzalez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Funder: Biotechnology and Biological Sciences Research Council East of Scotland Bioscience Doctoral Training Partnership Ph.D. studentship
Funder: Korean Institute for Basic Science, IBS-R022-A1-2019
Cells possess an armamentarium of DNA re
Funder: Korean Institute for Basic Science, IBS-R022-A1-2019
Cells possess an armamentarium of DNA re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102e6fd601736c1d88701a45c277fcd8
https://doaj.org/article/586f62ed751f4d509ab638e75a89c6f7
https://doaj.org/article/586f62ed751f4d509ab638e75a89c6f7
Autor:
Nadezda V. Volkova, Simone Bertolini, Anton Gartner, Peter J. Campbell, Moritz Gerstung, Bin Wang, Víctor González-Huici, Bettina Meier
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258269 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258269 (2021)
Ionizing radiation (IR) is widely used in cancer therapy and accidental or environmental exposure is a major concern. However, little is known about the genome-wide effects IR exerts on germ cells and the relative contribution of DNA repair pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5030415c22f8c04ba63e08aac36ba3
https://pubmed.ncbi.nlm.nih.gov/34614038
https://pubmed.ncbi.nlm.nih.gov/34614038
Autor:
Víctor González-Huici, Simon J. Boulton, Bettina Meier, Moritz Gerstung, Anton Gartner, N. N. Volkova, Ye Hong, Simone Bertolini, Tsvetana Petrova, Peter J. Campbell
Genome integrity is particularly important in germ cells to faithfully preserve genetic information across generations. As yet little is known about the contribution of various DNA repair pathways to prevent mutagenesis. Using theC. elegansmodel we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d1d7827a3d708d602da2f446976242b
https://doi.org/10.1101/2020.06.04.133306
https://doi.org/10.1101/2020.06.04.133306
Autor:
Angelo Franzè, Veronica Iori, Lucas G. Cavallaro, M. Maino, Simone Bertolini, Gioacchino Leandro, Giulia Martina Cavestro, Francesco Di Mario, Nadia Altavilla, Anna Ingegnoli, R. Merli
Publikováno v:
Fundamental and Clinical Pharmacology. 19:497-501
It has been reported in literature that serum pepsinogen levels rise during omeprazole and lansoprazole administration. However, the influence of pantoprazole and esomeprazole on serum pepsinogens levels is still to be assessed. The aim of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a072aade05dea5beb9946e907ef2f25e
https://doi.org/10.1111/j.1472-8206.2005.00348.x
https://doi.org/10.1111/j.1472-8206.2005.00348.x
Autor:
R. Merli, Simone Bertolini, Veronica Iori, Ali M. Moussa, Giulia Martina Cavestro, Francesco Di Mario, Gioacchino Leandro, Nadia Dal Bo, Angelo Franzè, Pietro Caruana, Lucas G. Cavallaro, Alberto Pilotto
Publikováno v:
Digestion. 70:167-172
Background: Serum pepsinogen II (sPGII) levels are known to increase during Helicobacter pylori infection. Aim: To assess H. pylori infection and success of H. pylori therapy by means of sPGII levels. Methods: sPGII levels were determined in 156 H. p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af2ed466c1b12a0f66dd1708083ac9aa
https://doi.org/10.1159/000081517
https://doi.org/10.1159/000081517
Autor:
Satish K. Singh, Gioacchino Leandro, Luca Frulloni, Mario Sianesi, S. Okolicsanyi, Giulia Martina Cavestro, Francesco Di Mario, Paolo Del Rio, Angelo Franzè, Giuliana Sereni, Raffaella Alessia Zuppardo, Simone Bertolini, C. Calzolari
OBJECTIVES: Acute, acute recurrent, and chronic pancreatitis are infl ammatory diseases with multifactorial pathogenic mechanisms. Genetic mutations and polymorphisms have been correlated with pancreatitis. The aim of this study was to investigate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a234bd14520ee577154c434c262fb454
http://hdl.handle.net/11562/770570
http://hdl.handle.net/11562/770570