Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Simone Benitz"'
Autor:
Ziying Jian, Tao Cheng, Zhiheng Zhang, Susanne Raulefs, Kuangyu Shi, Katja Steiger, Nadja Maeritz, Karin Kleigrewe, Thomas Hofmann, Simone Benitz, Philipp Bruns, Daniel Lamp, Martin Jastroch, Jan Akkan, Carsten Jäger, Peilin Huang, Shuang Nie, Shanshan Shen, Xiaoping Zou, Güralp O. Ceyhan, Christoph W. Michalski, Helmut Friess, Jörg Kleeff, Bo Kong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 429-449 (2018)
Background & Aims: Although nearly half of pancreatic ductal adenocarcinoma (PDAC) patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment is hypoglycemic. Thus, it is crucial for PDAC cells to develop adaptive mech
Externí odkaz:
https://doaj.org/article/a2ff2b7c8a4e4563ac1a648e6adcb65c
Autor:
Megan T. Hoffman, Samantha B. Kemp, Daniel J. Salas-Escabillas, Yaqing Zhang, Nina G. Steele, Stephanie The, Daniel Long, Simone Benitz, Wei Yan, Robert F. Margolskee, Filip Bednar, Marina Pasca di Magliano, Hui-Ju Wen, Howard C. Crawford
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Pancreatic ductal adenocarcinoma (PDA) initiation and progression are accompanied by an immunosuppressive inflammatory response. Here, we evaluated the immunomodulatory role of chemosensory signaling in metaplastic tuft cells (MTCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686c6a10eefc99372b1badab6334bce4
https://doi.org/10.1016/j.jcmgh.2020.08.011
https://doi.org/10.1016/j.jcmgh.2020.08.011
Autor:
Simone Benitz, Ian Loveless, Malak Nasser, Hui-Ju Wen, Daniel Long, Erick Davis, Jacee Moore, Tobias Straub, Ivonne Regel, Filip Bednar, Howard Crawford
Publikováno v:
Cancer Research. 82:B061-B061
Background: The major genetic driver for pancreatic ductal adenocarcinoma (PDAC) is oncogenic KRAS. However, adult acinar cells, a probable origin of PDAC, are largely refractory to KrasG12D-mediated oncogenic transformation in mouse models. With the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8a79a6b65e441285c307c77c6643ed
https://doi.org/10.1158/1538-7445.panca22-b061
https://doi.org/10.1158/1538-7445.panca22-b061
Autor:
U. Mahajan, Simone Benitz, Ivonne Regel, Lisa Fahr, Julia Mayerle, G. Beyer, J. Kleeff, Katja Steiger, H. Lisiecki, T. Straub, J. Mutter, Christoph W. Michalski
Publikováno v:
Pancreatology. 22:e75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4101e69a3853a95c2df8e090c5427faa
https://doi.org/10.1016/j.pan.2022.06.195
https://doi.org/10.1016/j.pan.2022.06.195
Autor:
Simone Benitz, Ian Loveless, Malak Nasser, Hui-Ju Wen, Daniel Long, Jacee Moore, Erick Davis, Tobias Straub, Ivonne Regel, Filip Bednar, Howard Crawford
Publikováno v:
Cancer Research. 82:790-790
Introduction: The major genetic driver for pancreatic ductal adenocarcinoma (PDAC) is oncogenic KRAS. However, adult acinar cells, the most probable origin of PDAC, are largely refractory to KrasG12D-mediated oncogenic transformation in conditional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::874d9b10d72cc69269e1462c69017cb8
https://doi.org/10.1158/1538-7445.am2022-790
https://doi.org/10.1158/1538-7445.am2022-790
Autor:
Howard C. Crawford, Simone Benitz
Publikováno v:
Gut. 71:1934-1935
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease and the seventh cause of cancer-related death worldwide.1 Notably, clinical characteristics, response to chemotherapy and progression of PDAC can vary among patients. Thus, huge efforts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c089dac1d13faa9425832703fdcb4d0
https://doi.org/10.1136/gutjnl-2021-325694
https://doi.org/10.1136/gutjnl-2021-325694
Autor:
Beate Hagl, Dietrich von Schweinitz, Christian Vokuhl, Ujjwal M. Mahajan, Roland Kappler, Melanie Eichenmüller, Simone Benitz, Ivonne Regel, Beate Häberle
Publikováno v:
J. Cancer Res. Clin. Oncol. 146, 1153-1167 (2020)
Journal of Cancer Research and Clinical Oncology
Journal of Cancer Research and Clinical Oncology
Background Hepatoblastoma (HB) and pediatric hepatocellular carcinoma (HCC) are the most common malignant liver tumors in childhood. Both tumor types exhibit genetic and epigenetic alterations in the WNT/β-catenin signaling pathway, which is a key r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc0e0f29b1568d5b0540bde30a7b6db
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58637
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58637
Autor:
Susanne Raulefs, Shanshan Shen, Katja Steiger, Daniel Lamp, Kuangyu Shi, Jan Akkan, Helmut Friess, Christoph W. Michalski, Nadja Maeritz, Jörg Kleeff, Philipp Bruns, Bo Kong, Shuang Nie, Tao Cheng, Martin Jastroch, Güralp O. Ceyhan, Simone Benitz, Thomas Hofmann, Xiaoping Zou, Ziying Jian, Carsten Jäger, Karin Kleigrewe, Peilin Huang, Zhiheng Zhang
Publikováno v:
Cell. Mol. Gast. Hept. 6, 429-449 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 429-449 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 429-449 (2018)
Background & Aims: Although nearly half of pancreatic ductal adenocarcinoma (PDAC) patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment is hypoglycemic. Thus, it is crucial for PDAC cells to develop adaptive mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e92c70ed437f3a4572f524b1dbc099
https://doi.org/10.1016/j.jcmgh.2018.07.003
https://doi.org/10.1016/j.jcmgh.2018.07.003
Autor:
Stefan Czemmel, Katja Steiger, Julia Mayerle, Ivonne Regel, Tatjana Unruh, Jörg Kleeff, Susanne Raulefs, Christoph W. Michalski, Irene Esposito, Britta Wingerath, Güralp O. Ceyhan, Simone Benitz, Bo Kong, Francisco X. Real, Sven Nahnsen, Sabrina Deubler
Publikováno v:
Zeitschrift für Gastroenterologie. 55:e1-e27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de214bb27c23078b983d68818f978c66
https://doi.org/10.1055/s-0037-1603059
https://doi.org/10.1055/s-0037-1603059
Publikováno v:
Expert Review of Anticancer Therapy. 16:219-227
Although the concept of tumor heterogeneity was established several decades ago, the interest in this topic is still unbroken. With the identification of inter- and intratumoral genomic rearrangements and the detection of cancer stem cells (CSCs) thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae659e49e28e244be6830f66362887c
https://doi.org/10.1586/14737140.2016.1129276
https://doi.org/10.1586/14737140.2016.1129276