Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Simone B, Sartori"'
Autor:
Simone B. Sartori, Thomas M. V. Keil, Kai K. Kummer, Conor P. Murphy, Ozge Gunduz-Cinar, Michaela Kress, Karl Ebner, Andrew Holmes, Nicolas Singewald
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The ventromedial prefrontal cortex (vmPFC; rodent infralimbic cortex (IL)), is posited to be an important locus of fear extinction-facilitating effects of the dopamine (DA) bio-precursor, L-DOPA, but this hypothesis remains to be formally te
Externí odkaz:
https://doaj.org/article/f6ceed42e2384d5bb6dbc4dc2f88ba60
Autor:
Bilge Ugursu, Anupam Sah, Simone B. Sartori, Helmut Kettenmann, Nicholas Singewald, Susanne A. Wolf
Publikováno v:
Journal of Affective Disorders Reports, Vol 12, Iss , Pp 100574- (2023)
Microglia are the first responders to disruptions in homeostasis as well as crucial players contributing to synaptic refinement in the central nervous system (CNS). We and others have previously reported alterations in microglia phenotype as well as
Externí odkaz:
https://doaj.org/article/96e3c0d954a54771aec2df1f4554ad8f
Autor:
Predrag Kalaba, Katharina Pacher, Philip John Neill, Vladimir Dragacevic, Martin Zehl, Judith Wackerlig, Michael Kirchhofer, Simone B. Sartori, Hubert Gstach, Shima Kouhnavardi, Anna Fabisikova, Matthias Pillwein, Francisco Monje-Quiroga, Karl Ebner, Alexander Prado-Roller, Nicolas Singewald, Ernst Urban, Thierry Langer, Christian Pifl, Jana Lubec, Johann Jakob Leban, Gert Lubec
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1415 (2023)
The high structural similarity, especially in transmembrane regions, of dopamine, norepinephrine, and serotonin transporters, as well as the lack of all crystal structures of human isoforms, make the specific targeting of individual transporters rath
Externí odkaz:
https://doaj.org/article/206825143bfe4497bebe4460b140ad5d
Autor:
Anupam Sah, Sinead Rooney, Maria Kharitonova, Simone B. Sartori, Susanne A. Wolf, Nicolas Singewald
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13052 (2022)
Neuroinflammation is discussed to play a role in specific subgroups of different psychiatric disorders, including anxiety disorders. We have previously shown that a mouse model of trait anxiety (HAB) displays enhanced microglial density and phagocyti
Externí odkaz:
https://doaj.org/article/c33f2f70857049d9bb347f6fc965fea3
Autor:
Karl Ebner, Simone B. Sartori, Rita Murau, Fabian Kopel, Predrag Kalaba, Vladimir Dragačević, Johann J. Leban, Nicolas Singewald, Mario Engelmann, Gert Lubec
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 506 (2022)
Previous studies have shown that atypical dopamine-transporter-inhibitors such as modafinil and its analogues modify behavioral and cognitive functions in rodents. Here, we tested potential promnestic effects of the novel, more dopamine-transporter s
Externí odkaz:
https://doaj.org/article/38f268bfe83643329910e4eb0788f786
Autor:
Judith Camats-Perna, Predrag Kalaba, Karl Ebner, Simone B. Sartori, Harish Vuyyuru, Nilima Y. Aher, Vladimir Dragačević, Nicolas Singewald, Mario Engelmann, Gert Lubec
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
In the laboratory, long-term social recognition memory (SRM) in mice is highly susceptible to proactive and retroactive interference. Here, we investigate the ability of novel designed dopamine (DA) re-uptake inhibitors (rac-CE-123 and S-CE-123) to b
Externí odkaz:
https://doaj.org/article/104ea673a7bd496b93a399f44e70ca3f
Autor:
Marija Ilic, Jana Lubec, Alexander Roller, Vladimir Dragačević, Jovana Malikovic, Shima Kouhnavardi, Johann Leban, Roberto Plasenzotti, Simone B. Sartori, Thierry Langer, Predrag Kalaba, Marco Pistis, Judith Wackerlig, Christian Pifl, Daniel Daba Feyissa, Martin Zehl, Karl Ebner, Nicolas Singewald, Ernst Urban, Claudia Sagheddu, Arthur Garon, Mohamed H. Kotob, Ahmed M. Hussein, Rasha Refaat Mahmmoud, Francisco J. Monje, Natalie Gajic, Anita Cybulska-Klosowicz, Oliver Wieder, Gert Lubec, Harald H. Sitte, Volker Korz
Publikováno v:
Molecular Psychiatry. 26:7076-7090
Aging-related neurological deficits negatively impact mental health, productivity, and social interactions leading to a pronounced socioeconomic burden. Since declining brain dopamine signaling during aging is associated with the onset of neurologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d36e133840b3bd448c5a3aff8da2b66
https://doi.org/10.1038/s41380-021-01214-x
https://doi.org/10.1038/s41380-021-01214-x
Publikováno v:
Neuropharmacology. 226:109418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ef687a89e5f4da671b37cbd91f8f3fc
https://doi.org/10.1016/j.neuropharm.2023.109418
https://doi.org/10.1016/j.neuropharm.2023.109418
Autor:
Michael S. Unger, Nicolas Singewald, Maria Kharitonova, Christoph Schwarzer, Susanne A. Wolf, Helmut Kettenmann, Sinead Rooney, Simone B. Sartori, Ludwig Aigner, Anupam Sah
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry
Translational Psychiatry
High trait anxiety is a substantial risk factor for developing anxiety disorders and depression. While neuroinflammation has been identified to contribute to stress-induced anxiety, little is known about potential dysregulation in the neuroinflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f363f2cdf1c79e9478b301e120d0d269
http://link.springer.com/article/10.1038/s41398-020-00942-y
http://link.springer.com/article/10.1038/s41398-020-00942-y
Autor:
Janine Maria Prast, Aurelia eSchardl, Simone B Sartori, Nicolas eSingewald, Alois eSaria, Gerald eZernig
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Anxiety disorders and substance use disorders are strongly associated in humans. Accordingly, a widely held but controversial concept in the addiction field, the so-called self-medication hypothesis, posits that anxious individuals are more vulnerabl
Externí odkaz:
https://doaj.org/article/d145acf29ebc4bc7a3620ffad31bb5bf