High-quality nuclear genome for Sarcoptes scabiei-A critical resource for a neglected parasite.

Autor: Pasi K Korhonen, Robin B Gasser, Guangxu Ma, Tao Wang, Andreas J Stroehlein, Neil D Young, Ching-Seng Ang, Deepani D Fernando, Hieng C Lu, Sara Taylor, Simone L Reynolds, Ehtesham Mofiz, Shivashankar H Najaraj, Harsha Gowda, Anil Madugundu, Santosh Renuse, Deborah Holt, Akhilesh Pandey, Anthony T Papenfuss, Katja Fischer

Publikováno v: PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008720 (2020)

The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin of humans and animals worldwide. In humans, this mite causes a neglected tropical disease (NTD), called scabies. This disease results in major morbidity,

Externí odkaz: https://doaj.org/article/12a8e16e28484afd90780687cbffde09

Gene silencing by RNA interference in Sarcoptes scabiei: a molecular tool to identify novel therapeutic targets

Autor: Deepani D. Fernando, Edward J. Marr, Martha Zakrzewski, Simone L. Reynolds, Stewart T. G. Burgess, Katja Fischer

Publikováno v: Parasites & Vectors, Vol 10, Iss 1, Pp 1-10 (2017)

Abstract Background Scabies is one of the most common and widespread parasitic skin infections globally, affecting a large range of mammals including humans, yet the molecular biology of Sarcoptes scabiei is astonishingly understudied. Research has b

Externí odkaz: https://doaj.org/article/7a576c0f2d174bb0b32bca0838988ffe

Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway.

Autor: Simone L Reynolds, Robert N Pike, Angela Mika, Anna M Blom, Andreas Hofmann, Lakshmi C Wijeyewickrema, Dave Kemp, Katja Fischer

Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2872 (2014)

Scabies is an infectious skin disease caused by the mite Sarcoptes scabiei and has been classified as one of the six most prevalent epidermal parasitic skin diseases infecting populations living in poverty by the World Health Organisation. The role o

Externí odkaz: https://doaj.org/article/706de1d5d44c43ed863bd5b2d19e78cb

Association between Urinary Triclosan and Serum Testosterone Levels in U.S. Adult Males from NHANES, 2011–2012

Autor: Michael A. Joseph, Simone A. Reynolds, Judy Yan, Laura A. Geer

Publikováno v: International Journal of Environmental Research and Public Health, Vol 17, Iss 7412, p 7412 (2020)
International Journal of Environmental Research and Public Health
Volume 17
Issue 20

Triclosan was introduced into the market in the 1970s and has since been used as an antimicrobial agent in a diverse array of consumer and personal care products. Although it has been widely used over a number of years, there is growing concern and d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfa555df0eb05687ef7d65357d12e00
https://www.mdpi.com/1660-4601/17/20/7412

Novel scabies mite serpins inhibit the three pathways of the human complement system.

Autor: Angela Mika, Simone L Reynolds, Frida C Mohlin, Charlene Willis, Pearl M Swe, Darren A Pickering, Vanja Halilovic, Lakshmi C Wijeyewickrema, Robert N Pike, Anna M Blom, David J Kemp, Katja Fischer

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40489 (2012)

Scabies is a parasitic infestation of the skin by the mite Sarcoptes scabiei that causes significant morbidity worldwide, in particular within socially disadvantaged populations. In order to identify mechanisms that enable the scabies mite to evade h

Externí odkaz: https://doaj.org/article/febdc3f5832d46f69ef210d1b47c34a3