Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Simone A. Beckham"'
Publikováno v:
BioTechniques, Vol 25, Iss 6, Pp 948-954 (1998)
Externí odkaz:
https://doaj.org/article/a5459dc124984dfd8d1b8e2521d5e7e2
Autor:
Rhys Grinter, Iain D Hay, Jiangning Song, Jiawei Wang, Don Teng, Vijay Dhanesakaran, Jonathan J Wilksch, Mark R Davies, Dene Littler, Simone A Beckham, Ian R Henderson, Richard A Strugnell, Gordon Dougan, Trevor Lithgow
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2006026 (2018)
Iron is essential for life. Accessing iron from the environment can be a limiting factor that determines success in a given environmental niche. For bacteria, access of chelated iron from the environment is often mediated by TonB-dependent transporte
Externí odkaz:
https://doaj.org/article/b67967ae50f746db9790b8745e356744
Autor:
Jacqueline A. Wilce, Bert L. Semler, Neelam Shah, Mehdi Y Matak, Matthew J Belousoff, Hans Elmlund, Hariprasad Venugopal, Naveen Vankadari, Joseph H. C. Nguyen, Matthew C.J. Wilce, Simone A. Beckham
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 48, iss 14
Nucleic acids research, vol 48, iss 14
The poliovirus type I IRES is able to recruit ribosomal machinery only in the presence of host factor PCBP2 that binds to stem–loop IV of the IRES. When PCBP2 is cleaved in its linker region by viral proteinase 3CD, translation initiation ceases al
Publikováno v:
Nucleic Acids Research
RIG-I (retinoic acid inducible gene-I) is a cytosolic innate immune protein that senses viral dsRNA with a 5′-triphosphate overhang. Upon interaction with dsRNA a de-repression of the RIG-I CARD domains takes place that ultimately leads to the prod
Autor:
Roberta B. Davies, Paul M. G. Curmi, James C. Walsh, Carina Glöckner, Stephen J. Harrop, Anna Sokolova, Anthony P. Duff, Ben Crossett, Juanita M. Phang, Simone A. Beckham, Elizabeth H. C. Bromley, Krystyna E. Wilk, Cuong D. Nguyen
Publikováno v:
Biochemical journal, 2016, Vol.473(18), pp.2763-2782 [Peer Reviewed Journal]
Ezrin is a member of the ERM (ezrin–radixin–moesin) family of proteins that have been conserved through metazoan evolution. These proteins have dormant and active forms, where the latter links the actin cytoskeleton to membranes. ERM proteins hav
Autor:
Vijay Dhanesakaran, Jonathan J. Wilksch, Richard A. Strugnell, Iain D. Hay, Trevor Lithgow, Jiawei Wang, Rhys Grinter, Ian R. Henderson, Gordon Dougan, Jiangning Song, Dene R. Littler, Mark R. Davies, Simone A. Beckham, Don Teng
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 8, p e2006026 (2018)
PLoS Biology, Vol 16, Iss 8, p e2006026 (2018)
Iron is essential for life. Accessing iron from the environment can be a limiting factor that determines success in a given environmental niche. For bacteria, access of chelated iron from the environment is often mediated by TonB-dependent transporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd2c409ebdc1da15815e094507cb682
https://www.repository.cam.ac.uk/handle/1810/285589
https://www.repository.cam.ac.uk/handle/1810/285589
Autor:
Corinne R Hitchen, Phillip Pymm, Richard Berry, Matthew C.J. Wilce, Shoeib Moradi, Julian P. Vivian, Hugh H. Reid, Simone A. Beckham, Jamie Rossjohn, Nicholas G Walpole, Matthew A. Perugini, Craig Steven Clements, Andrew G. Brooks
Publikováno v:
Journal of Biological Chemistry. 290:10460-10471
The engagement of natural killer cell immunoglobulin-like receptors (KIRs) with their target ligands, human leukocyte antigen (HLA) molecules, is a critical component of innate immunity. Structurally, KIRs typically have either two (D1-D2) or three (
Publikováno v:
Molecular Biology Reports. 41:7945-7953
DnaK plays a central role in stress response in the important human pathogen Neisseria gonorrhoeae. The genes encoding the DnaK chaperone machine (DnaK/DnaJ/GrpE) in N. gonorrhoeae are transcribed from RpoH (σ(32))-dependent promoters. In this study
Autor:
Alistair Miller, Weisan Chen, Matthias John, Ashley M. Jacobi, Jessica M Moffat, Bryan R.G. Williams, Soroush T. Sarvestani, Justine D. Mintern, Michael P. Gantier, Simone A. Beckham, Meredith O'Keeffe, Mark A. Behlke, Michelle D. Tate, Claire E. McCoy
Publikováno v:
Journal of Virology. 88:799-810
RNA-specific adenosine deaminase (ADAR)-mediated adenosine-to-inosine (A-to-I) editing is a critical arm of the antiviral response. However, mechanistic insights into how A-to-I RNA editing affects viral infection are lacking. We posited that inosine
Autor:
Galina Polekhina, Mark Waltham, Simone A. Beckham, David B. Ascher, Shie Foong Kok, Matthew C.J. Wilce
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 69:333-344
Thioredoxin-interacting protein (TXNIP) is one of the six known α-arrestins and has recently received considerable attention owing to its involvement in redox signalling and metabolism. Various stress stimuli such as high glucose, heat shock, UV, H2