Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Simone, Silberman"'
Publikováno v:
CNS Drug Reviews. 10:127-146
The causes of late onset Alzheimer disease (AD) are poorly understood. Although beta-amyloid (Abeta) is thought to play a critical role in the pathophysiology of AD, no genetic evidence directly ties Abeta to late onset AD. This suggests that the acc
Autor:
Simone Silberman
Publikováno v:
Archives of Pathology & Laboratory Medicine. 123:889-894
Objective.—To summarize current knowledge and recent progress pertaining to platelet concentrate preparations, modifications, and future prospects for platelet substitutes.Methods.—Current publications identified through a search of an electronic
Publikováno v:
Journal of Biological Chemistry. 274:801-813
Ras activates a multitude of downstream activities with roles in cellular proliferation, invasion and metastasis, differentiation, and programmed cell death. In this work we have evaluated the requirement of extracellular signal-regulated protein kin
Publikováno v:
Immunohematology. 20:187-189
A 24-year old female, gravida ΠI, para ΠI, delivered a full-term infant by cesarean section. A maternal blood sample at the time of admission showed antibody in her serum that had apparent anti-e specificity and that her RBCs were e+. Further studi
Publikováno v:
Brain Research. 610:108-114
Nerve growth factor receptor immunoreactivity (NGFRI) in the pineal gland was examined both light and electron microspically using the monoclonal antibody 192 IgG. NGFRI was located on sympathetic fibers and on perivascular cells resembling macrophag
Publikováno v:
Anticancer research. 24(6)
Increased expression of cathepsin B contributes to extracellular matrix degradation and invasion in cancer. Cathepsin B expression is under transcriptional control in murine melanomas and the major promoter contains potential binding sites for the Sp
A case of acute hemolysis after ceftriaxone: immune complex mechanism demonstrated by flow cytometry
Publikováno v:
Archives of pathologylaboratory medicine. 128(8)
An immune complex mechanism for ceftriaxone sodium– induced severe autoimmune hemolytic anemia has previously been demonstrated using routine blood bank techniques. We describe herein a patient with severe hemolysis that subsided once the drug was
Autor:
John M. Lee, Simone Silberman, Debra Yager, Allison B. Reiss, Kumar Sambamurti, Christopher B. Eckman, Janet Crowley, James Brown, Benjamin Wolozin, Mohammad M. Rahman, Catherine Theisler, Debra J. Magnuson, Numa R. Gottardi-Littell
Publikováno v:
The Journal of biological chemistry. 279(33)
Cholesterol is eliminated from neurons by oxidization, which generates oxysterols. Cholesterol oxidation is mediated by the enzymes cholesterol 24-hydroxylase (CYP46A1) and cholesterol 27-hydroxylase (CYP27A1). Immunocytochemical studies show that CY
Autor:
Gladell P, Paner, Simone, Silberman, Grace, Hartman, Kenneth C, Micetich, Gerard V, Aranha, Serhan, Alkan
Publikováno v:
Anticancer research. 23(3B)
Several signaling pathways have been recognized in normal c-kit-mediated signal transduction following stem cell factor (SCF) stimulation including Janus kinase (JAK)/signal transducer and activator of transcription (STAT), mitogen-activated protein
Publikováno v:
The Journal of biological chemistry. 272(9)
Invasive and metastatic cells require protease expression for migration through the extracellular matrix. Metastatic NIH 3T3 fibroblasts transformed by different activated ras genes showed two different protease phenotypes, rasuPA+/CL- and rasCL+/uPA