Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Simone, Picelli"'
Autor:
Ross Dobie, John R. Wilson-Kanamori, Beth E.P. Henderson, James R. Smith, Kylie P. Matchett, Jordan R. Portman, Karolina Wallenborg, Simone Picelli, Anna Zagorska, Swetha V. Pendem, Thomas E. Hudson, Minnie M. Wu, Grant R. Budas, David G. Breckenridge, Ewen M. Harrison, Damian J. Mole, Stephen J. Wigmore, Prakash Ramachandran, Chris P. Ponting, Sarah A. Teichmann, John C. Marioni, Neil C. Henderson
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1832-1847.e8 (2019)
Summary: Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells (HSCs) are a major source of pathological matrix during fibrosis and are thought to be
Externí odkaz:
https://doaj.org/article/3e037994cd354294a9745ce74fc85275
Autor:
Philipp Wahle, Giovanna Brancati, Christoph Harmel, Zhisong He, Gabriele Gut, Jacobo Sarabia del Castillo, Aline Xavier da Silveira dos Santos, Qianhui Yu, Pascal Noser, Jonas Simon Fleck, Bruno Gjeta, Dinko Pavlinić, Simone Picelli, Max Hess, Gregor W. Schmidt, Tom T. A. Lummen, Yanyan Hou, Patricia Galliker, David Goldblum, Marton Balogh, Cameron S. Cowan, Hendrik P. N. Scholl, Botond Roska, Magdalena Renner, Lucas Pelkmans, Barbara Treutlein, J. Gray Camp
Publikováno v:
Nature Biotechnology
Organoids generated from human pluripotent stem cells provide experimental systems to study development and disease, but quantitative measurements across different spatial scales and molecular modalities are lacking. In this study, we generated multi
Autor:
Alissa Muller, Jack Sullivan, Wibke Schwarzer, Mantian Wang, Cindy Park-Windhol, Beryll Klingler, Jane Matsell, Simon Hostettler, Patricia Galliker, Mert Duman, Yanyan Hou, Pierre Balmer, Tamás Virág, Luis Alberto Barrera, Quan Xu, Dániel Péter Magda, Ferenc Kilin, Arogya Khadka, Mathieu Quinodoz, Pascal W. Hasler, Pierre-Henri Moreau, Lyne Fellmann, Thierry Azoulay, Marco Cattaneo, Simone Picelli, Alice Grison, Cameron S. Cowan, Lucas Janeschitz-Kriegl, Ákos Kusnyerik, Magdalena Renner, Zoltán Zsolt Nagy, Arnold Szabó, Carlo Rivolta, Hendrik P.N. Scholl, David Bryson, Giuseppe Ciaramella, Botond Roska, Bence György
Stargardt disease is a currently untreatable, inherited neurodegenerative disease that leads to macular degeneration and blindness due to loss-of-function mutations in theABCA4gene. We have designed a dual adeno-associated viral vector split-intein a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd497ac7466dc48e5713f90aa2177981
https://doi.org/10.1101/2023.04.17.535579
https://doi.org/10.1101/2023.04.17.535579
Autor:
Simone Picelli
The single-cell RNA-sequencing (scRNA-seq) field has evolved tremendously since the first paper was published back in 2009. While the first methods analysed just a handful of cells, the throughput and performance rapidly increased over a very short t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db372e4b0a26c0fde54ec260f396156b
https://doi.org/10.17504/protocols.io.kxygxzkrwv8j/v4
https://doi.org/10.17504/protocols.io.kxygxzkrwv8j/v4
Autor:
Vincent Hahaut, Simone Picelli
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f470bcd70564502ee1d3d2fb08c170fa
https://doi.org/10.1007/978-1-0716-2756-3_5
https://doi.org/10.1007/978-1-0716-2756-3_5
Autor:
Martin Munz, Arjun Bharioke, Georg Kosche, Verónica Moreno-Juan, Alexandra Brignall, Alexandra Graff-Meyer, Talia Ulmer, Tiago M. Rodrigues, Stephanie Haeuselmann, Dinko Pavlinic, Nicole Ledergeber, Brigitte Gross-Scherf, Balázs Rózsa, Jacek Krol, Simone Picelli, Cameron S. Cowan, Botond Roska
SummaryCortical circuits are composed predominantly of pyramidal-to-pyramidal neuron connections, yet their assembly during embryonic development is not well understood. We show that embryonic layer 5 pyramidal neurons, identified through single cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff10fd6d26329121c189b3709769648
https://doi.org/10.1101/2022.08.31.506080
https://doi.org/10.1101/2022.08.31.506080
Autor:
Anna Morena, D'Alise, Nadia, Brasu, Carlo, De Intinis, Guido, Leoni, Valentina, Russo, Francesca, Langone, Denis, Baev, Elisa, Micarelli, Luca, Petiti, Simone, Picelli, Marwan, Fakih, Dung T, Le, Michael J, Overman, Anthony F, Shields, Katrina S, Pedersen, Manish A, Shah, Sarbajit, Mukherjee, Thea, Faivre, Patricia, Delaite, Elisa, Scarselli, Luigia, Pace
Publikováno v:
Sci Transl Med
Upon chronic antigen exposure, CD8(+) T cells become exhausted, acquiring a dysfunctional state correlated with the inability to control infection or tumor progression. In contrast, stem-like CD8(+) T progenitors maintain the ability to promote and s
Autor:
Martin Munz, Arjun Bharioke, Georg Kosche, Verónica Moreno-Juan, Alexandra Brignall, Tiago M. Rodrigues, Alexandra Graff-Meyer, Talia Ulmer, Stephanie Haeuselmann, Dinko Pavlinic, Nicole Ledergerber, Brigitte Gross-Scherf, Balázs Rózsa, Jacek Krol, Simone Picelli, Cameron S. Cowan, Botond Roska
Publikováno v:
Cell. 186:1930-1949.e31
Autor:
Simone Picelli, Vincent Hahaut
Building upon the existing Smart-seq2/3 workflows, we developed FLASH-seq (FS), a new full-length scRNA-seq method capable of detecting a significantly higher number of genes than both previous versions, requiring limited hands-on time and with a gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a30430c72d9489cb7301c18d0d986b6c
https://doi.org/10.17504/protocols.io.b6m2rc8e
https://doi.org/10.17504/protocols.io.b6m2rc8e
Autor:
Simone Picelli
The single-cell RNA-sequencing (scRNA-seq) field has evolved tremendously since the first paper was published back in 2009. While the first methods analysed just a handful of cells, the throughput and performance rapidly increased over a very short t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d06b4e84d6c2f1b86f28d23e64e4138
https://doi.org/10.17504/protocols.io.kxygxzkrwv8j/v3
https://doi.org/10.17504/protocols.io.kxygxzkrwv8j/v3