Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Simone, Mader"'
Autor:
Stephan Winklmeier, Heike Rübsamen, Ceren Özdemir, Paul R. Wratil, Gaia Lupoli, Marcel Stern, Celine Schneider, Katharina Eisenhut, Samantha Ho, Hoi Kiu Wong, Damla Taskin, Marvin Petry, Michael Weigand, Peter Eichhorn, Bärbel U. Foesel, Simone Mader, Oliver T. Keppler, Tania Kümpfel, Edgar Meinl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The mucosal immunity is crucial for restricting SARS-CoV-2 at its entry site. Intramuscularly applied vaccines against SARS-CoV-2 stimulate high levels of neutralizing Abs in serum, but the impact of these intramuscular vaccinations on features of mu
Externí odkaz:
https://doaj.org/article/9d42e7c5f3d24fc18847cc55adb70e1e
Autor:
Valerie E. Teschner, Ann-Katrin Fleck, Carolin Walter, Anna-Sophie Schwarze, Melanie Eschborn, Timo Wirth, Olga V. Steinberg, Andreas Schulte-Mecklenbeck, I-Na Lu, Marisol Herrera-Rivero, Claudia Janoschka, Jan D. Lünemann, Nicholas Schwab, Gerd Meyer zu Hörste, Julian Varghese, Catharina C. Gross, Refik Pul, Christoph Kleinschnitz, Simone Mader, Edgar Meinl, Monika Stoll, Heinz Wiendl, Luisa Klotz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Cladribine is a highly effective immunotherapy that is applied in two short-term courses over 2 years and reduces relapse rate and disease progression in patients with relapsing multiple sclerosis (MS). Despite the short treatment period,
Externí odkaz:
https://doaj.org/article/620f3b4ae03d47ceb2b1381faa850bb4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/d5bd069283164b7c81c0c76b83b8d13b
Rare variants and HLA haplotypes associated in patients with neuromyelitis optica spectrum disorders
Autor:
Inna Tabansky, Akemi J. Tanaka, Jiayao Wang, Guanglan Zhang, Irena Dujmovic, Simone Mader, Venkatesh Jeganathan, Tracey DeAngelis, Michael Funaro, Asaff Harel, Mark Messina, Maya Shabbir, Vishaan Nursey, William DeGouvia, Micheline Laurent, Karen Blitz, Peter Jindra, Mark Gudesblatt, Regeneron Genetics Center, Alejandra King, Jelena Drulovic, Edmond Yunis, Vladimir Brusic, Yufeng Shen, Derin B. Keskin, Souhel Najjar, Joel N. H. Stern
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neuromyelitis optica spectrum disorders (NMOSD) are rare, debilitating autoimmune diseases of the central nervous system. Many NMOSD patients have antibodies to Aquaporin-4 (AQP4). Prior studies show associations of NMOSD with individual Human Leukoc
Externí odkaz:
https://doaj.org/article/0949e2708c71481fbc1c38c531d3cb15
Autor:
Ramona Gerhards, Lena Kristina Pfeffer, Jessica Lorenz, Laura Starost, Luise Nowack, Franziska S. Thaler, Miriam Schlüter, Heike Rübsamen, Caterina Macrini, Stephan Winklmeier, Simone Mader, Mattias Bronge, Hans Grönlund, Regina Feederle, Hung-En Hsia, Stefan F. Lichtenthaler, Juliane Merl-Pham, Stefanie M. Hauck, Tanja Kuhlmann, Isabel J. Bauer, Eduardo Beltran, Lisa Ann Gerdes, Aleksandra Mezydlo, Amit Bar-Or, Brenda Banwell, Mohsen Khademi, Tomas Olsson, Reinhard Hohlfeld, Hans Lassmann, Tania Kümpfel, Naoto Kawakami, Edgar Meinl
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Autoimmune disorders of the central nervous system (CNS) comprise a broad spectrum of clinical entities. The stratification of patients based on the recognized autoantigen is of great importance for therapy optimization and for concepts of p
Externí odkaz:
https://doaj.org/article/48e9a477e7444c7f8deb69565051b888
Autor:
Stephan Winklmeier, Katharina Eisenhut, Damla Taskin, Heike Rübsamen, Ramona Gerhards, Celine Schneider, Paul R. Wratil, Marcel Stern, Peter Eichhorn, Oliver T. Keppler, Matthias Klein, Simone Mader, Tania Kümpfel, Edgar Meinl
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103659- (2022)
Summary: Although some COVID-19 patients maintain SARS-CoV-2-specific serum immunoglobulin G (IgG) for more than 6 months postinfection, others eventually lose IgG levels. We assessed the persistence of SARS-CoV-2-specific B cells in 17 patients, 5 o
Externí odkaz:
https://doaj.org/article/421780233e7e4232a603f35bf55f7e8d
Autor:
Sangita Khatri, Nikos Psaraftis, Alessia Funaro, Yoshiyuki Arinuma, Yuichiro Fujieda, Simone Mader, Dr., Ph.D., Christian Damsgaard Jørgensen, Kira Astakhova
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss , Pp 100068- (2020)
Neuropsychiatric systemic lupus erythematosus is an autoimmune disorder characterized by an irregular exchange between the central nervous system and the immune system, leading to the outbreak of neurological conditions with possible disabling effect
Externí odkaz:
https://doaj.org/article/497c413defd547d78961ac1d2455ae7e
Publikováno v:
Current Opinion in Neurology. 35:427-435
The purpose of this review is to highlight the recently emerging pathomechanisms of diseases associated with autoantibodies to AQP4, MOG, GFAP, GRP78 and further novel targets. We discuss novel biomarkers and therapeutic approaches.Although complemen
Autor:
Simone Mader, Samantha Ho, Hoi Kiu Wong, Selia Baier, Stephan Winklmeier, Carolina Riemer, Heike Rübsamen, Iris Marti Fernandez, Ramona Gerhards, Cuilian Du, Omar Chuquisana, Jan D. Lünemann, Anja Lux, Falk Nimmerjahn, Monika Bradl, Naoto Kawakami, Edgar Meinl
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) have recently been established to define a new disease entity, MOG-antibody-associated disease (MOGAD), which is clinically overlapping with multiple sclerosis. MOG-specific antibodies
Autor:
Fernando Sluchensci dos Santos, Renan Felipe Pereira Gonçalves, Simone Mader Dall’ Agnol, Claudia Bernardes Maganhini, Franciele Aparecida Amaral, Jessica Kot, Wagner Menna Pereira
Publikováno v:
Brazilian Journal of Development. 8:34869-34886
Podemos definir envelhecimento como um processo natural e inerente a todas as pessoas. O processo de envelhecimento apresenta como uma de suas consequências o declínio na força dos músculos esqueléticos bem como dos respiratórios, o que pode in