Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Simone, König"'
Autor:
I-Na Lu, Phyllis Fung-Yi Cheung, Michael Heming, Christian Thomas, Giovanni Giglio, Markus Leo, Merve Erdemir, Timo Wirth, Simone König, Christine A. Dambietz, Christina B. Schroeter, Christopher Nelke, Jens T. Siveke, Tobias Ruck, Luisa Klotz, Carmen Haider, Romana Höftberger, Christoph Kleinschnitz, Heinz Wiendl, Tim Hagenacker, Gerd Meyer zu Horste
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract 5q-associated spinal muscular atrophy (SMA) is a motoneuron disease caused by mutations in the survival motor neuron 1 (SMN1) gene. Adaptive immunity may contribute to SMA as described in other motoneuron diseases, yet mechanisms remain elus
Externí odkaz:
https://doaj.org/article/fb6284ab7fac4a1d86c729a732971fab
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract High-grade gliomas (HGG) carry a dismal prognosis. Diagnosis comprises MRI followed by histopathological evaluation of tissue; no blood biomarker is available. Patients are subjected to serial MRIs and, if unclear, surgery for monitoring of
Externí odkaz:
https://doaj.org/article/9ec011d4f7c84abda42dff6c4e37ce6a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Adipokinetic hormones (AKHs) in Arthopoda are characterized by special sequence features including limited choices of amino acid residues in certain positions, such as Trp in position 8. Over 100 different AKHs have been described, but de no
Externí odkaz:
https://doaj.org/article/431a544fc07e4593b4eedcfef5150293
Autor:
Simone König
Publikováno v:
Molecules, Vol 29, Iss 12, p 2847 (2024)
The genus Strophantus belongs to the Apocynaceae family of flowering plants which grows primarily in tropical Africa. The plants are widely used in traditional herbal medicine. S. sarmentosus, in particular, is used for the treatment of, e.g., joint
Externí odkaz:
https://doaj.org/article/363ea56998594dc797f0af2366ff0ca0
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1027 (2024)
The vasoactive peptide bradykinin (BK) is an important member of the renin–angiotensin system. Its discovery is tightly interwoven with snake venom research, because it was first detected in plasma following the addition of viper venom. While the f
Externí odkaz:
https://doaj.org/article/9a9056f563d04eacaccae0729e5209c5
Autor:
Eric Suero Molina, David Black, Anna Walke, Ghasem Azemi, Fabio D’Alessandro, Simone König, Walter Stummer
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
In glioma surgery, the low-density infiltration zone of tumors is difficult to detect by any means. While, for instance, 5-aminolevulinic acid (5-ALA)-induced fluorescence is a well-established surgical procedure for maximizing resection of malignant
Externí odkaz:
https://doaj.org/article/7434c0ca9716444ab934cbd89f78a31f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The visualization of protoporphyrin IX (PPIX) fluorescence with the help of surgical microscopes during 5-aminolevulinic acid-mediated fluorescence-guided resection (FGR) of gliomas is still limited at the tumor margins. Hyperspectral imagin
Externí odkaz:
https://doaj.org/article/487789e806b14bd1b5ba40d59275b19e
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 3, Pp 114-130 (2023)
Abstract CK2β is the non‐catalytic modulating part of the S/T‐protein kinase CK2. However, the overall function of CK2β is poorly understood. Here, we report on the identification of 38 new interaction partners of the human CK2β from lysates o
Externí odkaz:
https://doaj.org/article/adeb9892a74a4988956a459ad6021031
Publikováno v:
Proteomes, Vol 12, Iss 1, p 6 (2024)
Many challenges in proteomics result from the high-throughput nature of the experiments. This paper first presents pre-analytical problems, which still occur, although the call for standardization in omics has been ongoing for many years. This articl
Externí odkaz:
https://doaj.org/article/0ab010adfc5e4a38aecc8bb8c0d4afc6
Publikováno v:
Life, Vol 13, Iss 12, p 2315 (2023)
Background: Adipokinetic hormones (AKHs) regulate important physiological processes in insects. AKHs are short peptides with blocked termini and Trp in position 8. Often, proline occupies position 6. Few post-translational modifications have been fou
Externí odkaz:
https://doaj.org/article/29133174e19246168012ea50c4e64a0c