Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Simone, Gschwend"'
Autor:
Simone Gschwend, Frank S. Zollmann, Matthias Berse, Joachim Höchel, Stefan Klein, Barbara Schütt, Wiesinger Herbert
Publikováno v:
British Journal of Clinical Pharmacology. 80:1399-1410
Aims The present study was conducted to investigate the influence of the strong CYP3A4 inhibitor ketoconazole (KTZ) on the pharmacokinetics of drospirenone (DRSP) administered in combination with ethinylestradiol (EE) or estradiol (E2). Methods This
Pharmacokinetics and Imaging Properties of Gd-EOB-DTPA in Patients With Hepatic and Renal Impairment
Publikováno v:
Investigative Radiology. 46:556-566
The purpose of this study was to determine the pharmacokinetics (PKs), imaging properties, and safety of the liver-specific magnetic resonance (MR) imaging contrast agent gadoxetic acid disodium (Gd-EOB-DTPA) in subjects with various levels of hepati
Autor:
Renate Hammerstingl, Alexander Huppertz, Stefan G. Ruehm, Philip Robinson, Gertraud Heinz-Peer, F. K. Schaefer, Christoph J. Zech, Bernd Tombach, Olivier Lucidarme, Luigi Grazioli, Edward Leen, Pierre-Jean Valette, Thomas Kittner, Josy Breuer, Antonella Filippone, Anthony Blakeborough, Christoforos Stoupis, Philipp Remplik, Simone Gschwend, Riccardo Lencioni, Andrea Laghi
Publikováno v:
Journal of Magnetic Resonance Imaging. 31:356-364
Purpose: To compare enhancement of liver parenchyma in MR imaging after injection of hepatocyte-specific contrast media. Materials and Methods: Patients (n = 295) with known/suspected focal liver lesions randomly received 0.025 mmol gadoxetic acid/kg
Autor:
Simone Gschwend, Lars Rothermund, Peter Kossmehl, Marc Nierhaus, Angela Schulz, Roland Vetter, Hans-Dieter Orzechowski, Marcel Haug, Reinhold Kreutz, Jürgen Scholze
Publikováno v:
Life Sciences. 85:431-437
In patients with renal disease the cardiovascular risk is greatly increased, and endothelial dysfunction is assumed to play a pivotal role in this process. Therefore we compared treatment effects of a beta-blocker with additional vasodilatory capacit
Autor:
Herbert, Wiesinger, Matthias, Berse, Stefan, Klein, Simone, Gschwend, Joachim, Höchel, Frank S, Zollmann, Barbara, Schütt
Publikováno v:
British journal of clinical pharmacology. 80(6)
The present study was conducted to investigate the influence of the strong CYP3A4 inhibitor ketoconazole (KTZ) on the pharmacokinetics of drospirenone (DRSP) administered in combination with ethinylestradiol (EE) or estradiol (E2).This was a randomiz
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics, 310(3), 1183-1189. WILLIAMS & WILKINS
Low dietary sodium (LS) increases the effect of angiotensin-converting enzyme (ACE) inhibitor therapy in patients and experimental models, but mechanisms underlying this enhanced efficacy are largely unknown. Because the benefits of ACE inhibition ar
Autor:
de Dick Zeeuw, Robert H. Henning, Hendrik Buikema, van Wiekert Gilst, YM Pinto, Simone Gschwend
Publikováno v:
British Journal of Pharmacology. 139:1317-1325
(1) Increased vascular resistance in chronic heart failure (CHF) has been attributed to stimulated neurohumoral systems. However, local mechanisms may also importantly contribute to set arterial tone. Our aim, therefore, was to test whether pressure-
Autor:
Roland Vetter, Rüdiger von Harsdorf, Hans-Dieter Orzechowski, Martin Stula, Martin Paul, Simone Gschwend, Rainer Dietz
Publikováno v:
Molecular and Cellular Biochemistry. 210:101-108
Restenosis after initially successful balloon angioplasty of coronary artery stenosis remains a major problem in clinical cardiology. Previous studies have identified pathogenetic factors which trigger cell proliferation and vascular remodeling ultim
Autor:
Josy Breuer, David R. Feldman, Jeff L. Fidler, Christopher Leary, Simone Gschwend, Isaac R. Francis, Jeffrey M. Brody, Eric K. Outwater, Richard C. Semelka, Donald G. Mitchell, Kohkan Shamsi, Marco A. Amendola, David A. Bluemke, Dushyant V. Sahani, Jeffrey D. McTavish, Steven S. Raman, Douglas H. Sheafor
OBJECTIVES To evaluate the safety of gadoxetic acid disodium (Gd-EOB-DTPA) magnetic resonance imaging (MRI) and its efficacy in characterizing liver lesions. METHODS Lesion characterization and classification using combined (unenhanced and Gd-EOB-DTP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea27efe0cd7a2461b9bfe8e875d63b3
Autor:
Luigi Grazioli, Christoph J. Zech, M. Ekman, Simone Gschwend, Josy Breuer, S. Kienbaum, L. Jönsson, R. Niebecker, Eduard Jonas
Publikováno v:
European radiology. 19
The purpose of this study was to perform an economic evaluation of hepatocyte-specific Gd-EOB-DTPA enhanced MRI (PV-MRI) compared to extracellular contrast-media-enhanced MRI (ECCM-MRI) and three-phase-MDCT as initial modalities in the work-up of pat