Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Simone, Detre"'
Autor:
Judith M. Bliss, Holly Tovey, Abigail Evans, Chris Holcombe, Kieran Horgan, Elizabeth Mallon, Raghavan Vidya, Anthony Skene, Andrew Dodson, Margaret Hills, Simone Detre, Lila Zabaglo, Jane Banerji, Lucy Kilburn, James P. Morden, John F. R. Robertson, Ian Smith, Mitch Dowsett, the POETIC Trialists
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Purpose Ki67 assessed at diagnosis (Ki67baseline) is an important prognostic factor in primary oestrogen receptor-positive (ER +) breast cancer. Proportional change in Ki67 after 2 weeks (∆Ki672week) is associated with clinical benefit fro
Externí odkaz:
https://doaj.org/article/46abcee1eee44a268049c2e73c029025
Autor:
Elena Lopez-Knowles, Simone Detre, Margaret Hills, Eugene F. Schuster, Maggie C. U. Cheang, Holly Tovey, Lucy S. Kilburn, Judith M. Bliss, John Robertson, Elizabeth Mallon, Anthony Skene, Abigail Evans, Ian Smith, Mitch Dowsett
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Background In clinical practice, oestrogen receptor (ER) analysis is almost entirely by immunohistochemistry (IHC). ASCO/CAP recommends cut-offs of
Externí odkaz:
https://doaj.org/article/b69c05c893f24935a330283cbc7187d8
Autor:
Kimberly J. Cocce, Jeff S. Jasper, Taylor K. Desautels, Logan Everett, Suzanne Wardell, Thomas Westerling, Robert Baldi, Tricia M. Wright, Kendall Tavares, Alex Yllanes, Yeeun Bae, Jeremy T. Blitzer, Craig Logsdon, Daniel P. Rakiec, David A. Ruddy, Tiancong Jiang, Gloria Broadwater, Terry Hyslop, Allison Hall, Muriel Laine, Linda Phung, Geoffrey L. Greene, Lesley-Ann Martin, Sunil Pancholi, Mitch Dowsett, Simone Detre, Jeffrey R. Marks, Gregory E. Crawford, Myles Brown, John D. Norris, Ching-yi Chang, Donald P. McDonnell
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 889-903.e10 (2019)
Summary: Notwithstanding the positive clinical impact of endocrine therapies in estrogen receptor-alpha (ERα)-positive breast cancer, de novo and acquired resistance limits the therapeutic lifespan of existing drugs. Taking the position that resista
Externí odkaz:
https://doaj.org/article/c0b467352d604bac96892990f6f1dd91
Autor:
Mitchell Dowsett, Adrian L. Harris, Ian E. Smith, Janine Salter, Simone Detre, Tim Dexter, Helen Anderson, Anita K. Dunbier, Francesca M. Buffa, Zara Ghazoui
Purpose: The majority of breast cancer patients who have estrogen receptor positive (ER+) tumors whose proliferation is reduced after estrogen deprivation by aromatase inhibitors (AI). This study investigates any link between proliferation and hypoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b405459bf5288588174f4eac3a28b72
https://doi.org/10.1158/1078-0432.c.6518916.v1
https://doi.org/10.1158/1078-0432.c.6518916.v1
Autor:
Stephen R.D. Johnston, Mitch Dowsett, Lesley-Ann Martin, Anne E. Lykkesfeldt, Sunil Pancholi, Simone Detre, Suzanne Drury, Alexandra F. Leary
Supplementary Data from Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8b40269c9aa7cd9c3acf817ce306b4
https://doi.org/10.1158/1078-0432.22439824.v1
https://doi.org/10.1158/1078-0432.22439824.v1
Autor:
Mitch Dowsett, Ian Smith, Gill Coombes, Nigel Bundred, Catherine Harper-Wynne, Margaret Hills, Benjamin P. Haynes, Simone Detre, Rashmita Sahoo, Judith M. Bliss, Roger A'Hern, Stephen R.D. Johnston, Abigail Evans, Alexandra Leary
Supplementary Table 3. Correlation between baseline protein and mRNA expression biomarker values with Ki67 response (defined as >50% fall in Ki67).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fdb4d4f00b509a7bf58d03d6d990c1
https://doi.org/10.1158/1078-0432.22456916
https://doi.org/10.1158/1078-0432.22456916
Autor:
Lesley-Ann Martin, Mitchell Dowsett, Dean B. Evans, Amanda J. Littlewood-Evans, Simone Detre, Roger A'Hern, Susana Banerjee
Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eab65d673ea715831407efdf50e1522
https://doi.org/10.1158/1078-0432.22442943.v1
https://doi.org/10.1158/1078-0432.22442943.v1
Autor:
Stephen R.D. Johnston, Mitch Dowsett, Angela Howes, Stan Kaye, Simone Detre, Emma Quinn, Janine Salter, Sunil Pancholi, Julia E. Head, Lesley-Ann Martin
PDF file - 51K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191866551df6671c9e9cbf1af85cd040
https://doi.org/10.1158/1535-7163.22485174
https://doi.org/10.1158/1535-7163.22485174
Autor:
Mitch Dowsett, Ian Smith, Gill Coombes, Nigel Bundred, Catherine Harper-Wynne, Margaret Hills, Benjamin P. Haynes, Simone Detre, Rashmita Sahoo, Judith M. Bliss, Roger A'Hern, Stephen R.D. Johnston, Abigail Evans, Alexandra Leary
Supplementary Table and Figure Legends. A list of all the supplementary table and figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a435e3cd0dd34f540b9e6bbde43e52
https://doi.org/10.1158/1078-0432.22456910.v1
https://doi.org/10.1158/1078-0432.22456910.v1
Autor:
Stephen R.D. Johnston, Mitch Dowsett, Angela Howes, Stan Kaye, Simone Detre, Emma Quinn, Janine Salter, Sunil Pancholi, Julia E. Head, Lesley-Ann Martin
PDF file - 68K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525aed77a611bc2b2b29ec8ef9db34fe
https://doi.org/10.1158/1535-7163.22485177.v1
https://doi.org/10.1158/1535-7163.22485177.v1