Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Simonas Masiulis"'
Autor:
Thomas Fontaine, Andreas Busch, Toon Laeremans, Stéphane De Cesco, Yi-Lynn Liang, Veli-Pekka Jaakola, Zara Sands, Sarah Triest, Simonas Masiulis, Lies Dekeyzer, Noor Samyn, Nicolas Loeys, Lisa Perneel, Melanie Debaere, Murielle Martini, Charlotte Vantieghem, Richa Virmani, Kamila Skieterska, Stephanie Staelens, Rosa Barroco, Maarten Van Roy, Christel Menet
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The melanocortin receptor 4 (MC4R) belongs to the melanocortin receptor family of G-protein coupled receptors and is a key switch in the leptin-melanocortin molecular axis that controls hunger and satiety. Brain-produced hormones such as α-
Externí odkaz:
https://doaj.org/article/f05dbb65117040f98bbf56edfbe2bf19
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2019)
Interactions between genetic and environmental risk factors take center stage in the pathology of schizophrenia. We assessed if the stressor of reduced environmental enrichment applied in adulthood provokes deficits in the positive, negative or cogni
Externí odkaz:
https://doaj.org/article/049e5537f0af46aa9199a3c34af969fc
Autor:
Anna J. Kiss-Szemán, Luca Takács, Zoltán Orgován, Pál Stráner, Imre Jákli, Gitta Schlosser, Simonas Masiulis, Veronika Harmat, Dóra K. Menyhárd, András Perczel
Publikováno v:
Chemical science. 13(48)
The structure of porcine AAP (pAAP) in a covalently bound complex with meropenem was determined by cryo-EM to 2.1 Å resolution, showing the mammalian serine-protease inhibited by a carbapenem antibiotic. AAP is a modulator of the ubiquitin-proteasom
Autor:
Simonas Masiulis, Jan Staníček, Ondřej Sháněl, Miloš Malínský, Oliver Raschdorf, Daniel Němeček
Publikováno v:
Microscopy and Microanalysis. 28:1170-1171
Autor:
Andrija Sente, Rooma Desai, Katerina Naydenova, Tomas Malinauskas, Youssef Jounaidi, Jonas Miehling, Xiaojuan Zhou, Simonas Masiulis, Steven W. Hardwick, Dimitri Y. Chirgadze, Keith W. Miller, A. Radu Aricescu
Publikováno v:
Nature
Type-A γ-aminobutyric acid receptors (GABA(A)Rs) are pentameric ligand-gated chloride channels that mediate fast inhibitory signalling in neural circuits( 1,2 ) and are modulated by essential medicines including general anaesthetics and benzodiazepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f928e59bd5199c06fca89677a54a4c
https://europepmc.org/articles/PMC7612593/
https://europepmc.org/articles/PMC7612593/
Autor:
Simonas Masiulis, Rooma Desai, Tomasz Uchański, Itziar Serna Martin, Duncan Laverty, Dimple Karia, Tomas Malinauskas, Jasenko Zivanov, Els Pardon, Abhay Kotecha, Jan Steyaert, Keith W. Miller, A. Radu Aricescu
Publikováno v:
Nature
Type-A γ-aminobutyric (GABAA) receptors are ligand-gated chloride channels with a very rich pharmacology. Some of their modulators, including benzodiazepines and general anaesthetics, are among the most successful drugs in clinical use and are commo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99ddfc1e90bf2f8c4ef5adae2031142
https://hdl.handle.net/20.500.14017/f9fb4511-ea37-4521-ab26-627d95b587ef
https://hdl.handle.net/20.500.14017/f9fb4511-ea37-4521-ab26-627d95b587ef
Autor:
Itziar Serna Martin, Narin Hengrung, Max Renner, Jane Sharps, Mónica Martínez-Alonso, Simonas Masiulis, Jonathan M. Grimes, Ervin Fodor
Publikováno v:
Molecular Cell
Summary Influenza virus RNA polymerase (FluPol), a heterotrimer composed of PB1, PB2, and PA subunits (P3 in influenza C), performs both transcription and replication of the viral RNA genome. For transcription, FluPol interacts with the C-terminal do
Autor:
Frederic Garzoni, Thomas Bock, Matthias W. Hentze, Karine Huard, Andreas E. Kulozik, Aurélien Deniaud, Simonas Masiulis, Martin Beck, Manikandan Karuppasamy, Gabriele Neu-Yilik, Kathrin Kerschgens, Christiane Schaffitzel
Publikováno v:
Nucleic Acids Research
Mammalian nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that degrades mRNAs containing premature translation termination codons. Phosphorylation of the essential NMD effector UPF1 by the phosphoinositide-3-kinase-like kina
Autor:
Ian Collinson, Alice Robson, Joanna Komar, Robin A. Corey, William J. Allen, Simonas Masiulis, Sam Menzies
Publikováno v:
Corey, R A, Allen, W J, Komar, J, Masiulis, S, Menzies, S, Robson, A & Collinson, I R 2016, ' Unlocking the bacterial SecY translocon ', Structure, vol. 24, pp. 1-10 . https://doi.org/10.1016/j.str.2016.02.001
Structure(London, England:1993)
Structure(London, England:1993)
Summary The Sec translocon performs protein secretion and membrane protein insertion at the plasma membrane of bacteria and archaea (SecYEG/β), and the endoplasmic reticular membrane of eukaryotes (Sec61). Despite numerous structures of the complex,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1f058e3622e891de4d2587894a64a5
https://research-information.bris.ac.uk/en/publications/3453f329-c3ca-4366-a47c-1deba82c18d7
https://research-information.bris.ac.uk/en/publications/3453f329-c3ca-4366-a47c-1deba82c18d7