Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Simona Sestito"'
Autor:
Alessandra Spagnolo, Vincenzo Mileto, Adele Civino, Maria Cristina Maggio, Paolo Risso, Simona Sestito, Romina Gallizzi
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundPeriodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA) is the most common cause of periodic fever in childhood. Although PFAPA is generally a self-limited condition, it can have negative impact on child's an
Externí odkaz:
https://doaj.org/article/efba615026104960bcc85b86fe9aafe0
Autor:
Federico Riu, Roberta Ibba, Stefano Zoroddu, Simona Sestito, Michele Lai, Sandra Piras, Luca Sanna, Valentina Bordoni, Luigi Bagella, Antonio Carta
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2223-2240 (2022)
Introduction: Colchicine-binding site inhibitors are some of the most interesting ligands belonging to the wider family of microtubule-destabilising agents.Results: A novel series of 4′-fluoro-substituted ligands (5–13) was synthesised. The antip
Externí odkaz:
https://doaj.org/article/3146be1fa5764644947125552e4d52ee
Autor:
Simona Sestito, Giada Rinninella, Angelica Rampazzo, Francesca D’Avanzo, Lucia Zampini, Lucia Santoro, Orazio Gabrielli, Agata Fiumara, Rita Barone, Nicola Volpi, Maurizio Scarpa, Rosella Tomanin, Daniela Concolino
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Mucopolysaccharidoses (MPSs) are a group of lysosomal storage disorders caused by the deficit of lysosomal hydrolases involved in the degradation of glycosaminoglycans (GAGs). The course is chronic and progressive, with multisyste
Externí odkaz:
https://doaj.org/article/385edfbf75f64cfe8275dc6a89d9cb43
Autor:
Javad Sharifi-Rad, Cristina Quispe, Monica Butnariu, Lia Sanda Rotariu, Oksana Sytar, Simona Sestito, Simona Rapposelli, Muhammad Akram, Mehwish Iqbal, Akash Krishna, Nanjangud Venkatesh Anil Kumar, Susana S. Braga, Susana M. Cardoso, Karolina Jafernik, Halina Ekiert, Natália Cruz-Martins, Agnieszka Szopa, Marcelo Villagran, Lorena Mardones, Miquel Martorell, Anca Oana Docea, Daniela Calina
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-21 (2021)
Abstract The study describes the current state of knowledge on nanotechnology and its utilization in medicine. The focus in this manuscript was on the properties, usage safety, and potentially valuable applications of chitosan-based nanomaterials. Ch
Externí odkaz:
https://doaj.org/article/ac9dc371255a4f8db9439b66372d4632
Autor:
Roberta Ibba, Paola Corona, Francesca Nonne, Paola Caria, Gabriele Serreli, Vanessa Palmas, Federico Riu, Simona Sestito, Maria Nieddu, Roberta Loddo, Giuseppina Sanna, Sandra Piras, Antonio Carta
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 429 (2023)
Several human diseases are caused by enteroviruses and are currently clinically untreatable, pushing the research to identify new antivirals. A notable number of benzo[d][1,2,3]triazol-1(2)-yl derivatives were designed, synthesized, and in vitro eval
Externí odkaz:
https://doaj.org/article/4176f5897e514b6d9e9884b6427fb6e4
Autor:
Maria Scavone, Laura Giancotti, Elisa Anastasio, Licia Pensabene, Simona Sestito, Daniela Concolino
Publikováno v:
Pediatrics and Neonatology, Vol 61, Iss 6, Pp 629-636 (2020)
Background: Congenital hypothyroidism (CH) is reported to be more common in preterm infants than in term infants, especially in sick preterm infants. Though a frequent possibility of transitory thyroidal alterations in this category of neonates, the
Externí odkaz:
https://doaj.org/article/734e3e5eeaa742f6a0c352a0a8c492d9
Autor:
Aikaterini Emmanouilidi, Chanse A. Fyffe, Riccardo Ferro, Charlotte E. Edling, Emily Capone, Simona Sestito, Simona Rapposelli, Rossano Lattanzio, Stefano Iacobelli, Gianluca Sala, Tania Maffucci, Marco Falasca
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Background The very aggressive nature and low survival rate of pancreatic ductal adenocarcinoma (PDAC) dictates the necessity to find novel efficacious therapies. Recent evidence suggests that phosphoinositide 3-kinase (PI3K) and 3-phosphoin
Externí odkaz:
https://doaj.org/article/7a7c4d16610446cf847b2d32f06af08d
Autor:
Federico Riu, Alessandro Ruda, Roberta Ibba, Simona Sestito, Ilenia Lupinu, Sandra Piras, Göran Widmalm, Antonio Carta
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 942 (2022)
Certain bacteria constitute a threat to humans due to their ability to escape host defenses as they easily develop drug resistance. Bacteria are classified into gram-positive and gram-negative according to the composition of the cell membrane structu
Externí odkaz:
https://doaj.org/article/f8dc503de5c04460bc330b27994a5d89
Autor:
Daniele Caracciolo, Antonio Giordano, Pierfrancesco Tassone, Caterina Riillo, Andrea Ballerini, Giuseppe Gaipa, Ludovic Lhermitte, Marco Rossi, Eugénie Duroyon, Katia Grillone, Maria Eugenia Gallo Cantafio, Chiara Buracchi, Greta Alampi, Alessandro Gulino, Beatrice Belmonte, Francesco Conforti, Gaetanina Golino, Giada Juli, Emanuela Altomare, Nicoletta Polerà, Francesca Scionti, Mariamena Arbitrio, Michelangelo Iannone, Massimo Martino, Gabriella Talarico, Andrea Ghelli Luserna di Rorà, Anna Ferrari, Simona Sestito, Licia Pensabene, Markus Hildinger, Maria Teresa Di Martino, Giovanni Martinelli, Claudio Tripodo, Vahid Asnafi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease with a poor cure rate for relapsed/resistant patients. Due to the lack of T-cell restricted targetable antigens, effective immune-therapeutics are not presently available
Externí odkaz:
https://doaj.org/article/0f25d9ba461c48ab8d7bd5afee32ce26
Autor:
Simona Sestito, Enza D'Auria, Maria Elisabetta Baldassarre, Silvia Salvatore, Valeria Tallarico, Ettore Stefanelli, Flora Tarsitano, Daniela Concolino, Licia Pensabene
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Allergic diseases have been linked to genetic and/or environmental factors, such as antibiotic use, westernized high fat and low fiber diet, which lead to early intestinal dysbiosis, and account for the rise in allergy prevalence, especially in weste
Externí odkaz:
https://doaj.org/article/8a9d512d49fa40b1b7fecb663d49ac07