Zobrazeno 1 - 10
of 32 431
pro vyhledávání: '"Simona S"'
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105771- (2022)
Despite the increasing number of studies on Parkinson's disease and it being the second most common neurodegenerative disorder in the world, no established diagnostic markers or disease modifying therapies are available. Understanding the mechanisms
Externí odkaz:
https://doaj.org/article/b8a8c9e0cc10421a860d41d07ba8f3ed
Autor:
Mustafa T. Ardah, Simona S. Ghanem, Sara A. Abdulla, Guohua Lv, Mohamed M. Emara, Katerina E. Paleologou, Nishant N. Vaikath, Jia-Hong Lu, Min Li, Konstantinos Vekrellis, David Eliezer, Omar M. A. El-Agnaf
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-21 (2020)
Abstract Background Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with
Externí odkaz:
https://doaj.org/article/20d1bd5274794f01b0343a5862a81e46
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
The nuclease activity of the CRISPR-Cas9 system relies on the delivery of a CRISPR-associated protein 9 (Cas9) and a single guide RNA (sgRNA) against the target gene. CRISPR components are typically delivered to cells as either a Cas9/sgRNA ribonucle
Externí odkaz:
https://doaj.org/article/c2a184203bee41af960b1c1a28b923a2
Autor:
Simona S. Capomolla, Giacomo Manfroni, Alessandro Prescimone, Edwin C. Constable, Catherine E. Housecroft
Publikováno v:
Molecules, Vol 27, Iss 15, p 4995 (2022)
The consistent assembly of a (65.8) cds net is observed in reactions of cobalt(II) thiocyanate with 1,4-bis(n-alkyloxy)-2,5-bis(3,2′:6′,3″-terpyridin-4′-yl)benzene ligands in which the n-alkyloxy substituents are n-propyl (ligand 3), n-butyl
Externí odkaz:
https://doaj.org/article/2b38e1ac8a9b45b8a7d325966a26aa48
Autor:
Daniel Sur, Loredana Balacescu, Simona S. Cainap, Simona Visan, Laura Pop, Claudia Burz, Andrei Havasi, Rares Buiga, Calin Cainap, Alexandru Irimie, Ovidiu Balacescu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
MicroRNAs (miRNAs), a class of small non-coding RNAs represent potential biomarkers for colorectal cancer (CRC). The study hypothesized that miRNAs associated with liver metastases may also contribute to assessing treatment response when associated t
Externí odkaz:
https://doaj.org/article/e71b9bbcac494ed9ac10623732919f6d
Autor:
Giacomo Manfroni, Simona S. Capomolla, Alessandro Prescimone, Edwin C. Constable, Catherine E. Housecroft
Publikováno v:
Inorganics, Vol 9, Iss 7, p 54 (2021)
The isomers 4′-(4-(trifluoromethyl)phenyl)-4,2′:6′,4″-terpyridine (1), 4′-(3-(trifluoromethyl)phenyl)-4,2′:6′,4″-terpyridine (2), 4′-(4-(trifluoromethyl)phenyl)-3,2′:6′,3″-terpyridine (3), and 4′-(3-(trifluoromethyl)phenyl)-
Externí odkaz:
https://doaj.org/article/8a50204b9f594bf7a5be7521bd564433
Autor:
Simona S. Ghanem, Hend S. Fayed, Qi Zhu, Jia-Hong Lu, Nishant N. Vaikath, Janarthanan Ponraj, Said Mansour, Omar M. A. El-Agnaf
Publikováno v:
Molecules, Vol 26, Iss 12, p 3736 (2021)
The accumulation and aggregation of α-synuclein (α-syn) is the main pathologic event in Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. α-Syn-seeded fibril formation and its induced toxicity occupy a major role
Externí odkaz:
https://doaj.org/article/340f359f92b643dab08028d648431a56
Autor:
Lucia Russo, Hilda E. Ghadieh, Simona S. Ghanem, Qusai Y. Al-Share, Zachary N. Smiley, Cara Gatto-Weis, Emily L. Esakov, Marcia F. McInerney, Garrett Heinrich, Xin Tong, Lei Yin, Sonia M. Najjar
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 12, Pp 2163-2175 (2016)
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance and mediating suppression of fatty acid synthase activity. Feeding C57BL/6J male mice with a high-fat (HF) diet f
Externí odkaz:
https://doaj.org/article/f7f6fe2e102a48d98a2c1e9bb9c83e65
Autor:
Daniela Sarnataro, Anna Caputo, Philippe Casanova, Claudia Puri, Simona Paladino, Simona S Tivodar, Vincenza Campana, Carlo Tacchetti, Chiara Zurzolo
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5829 (2009)
BACKGROUND:The cellular prion protein (PrP(C)) plays a key role in the pathogenesis of Transmissible Spongiform Encephalopathies in which the protein undergoes post-translational conversion to the infectious form (PrP(Sc)). Although endocytosis appea
Externí odkaz:
https://doaj.org/article/d4e5b6c14de444668997aa87a5840bc7
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